BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

105 related articles for article (PubMed ID: 21384493)

  • 1. Evaluation of chlorinated benz[a]anthracene on hepatic toxicity in rats and mutagenic activity in Salmonella typhimurium.
    Kido T; Sakakibara H; Ohura T; Guruge KS; Kojima M; Hasegawa J; Iwamura T; Yamanaka N; Masuda S; Sakaguchi M; Amagai T; Shimoi K
    Environ Toxicol; 2013 Jan; 28(1):21-30. PubMed ID: 21384493
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Organ-specific distribution of 7-chlorinated benz[a]anthracene and regulation of selected cytochrome P450 genes in rats.
    Sakakibara H; Ohura T; Kido T; Yamanaka N; Tanimura N; Shimoi K; Guruge KS
    J Toxicol Sci; 2013 Feb; 38(1):137-43. PubMed ID: 23358148
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of human cytochrome P450 1A1-, 1A2-, and 1B1-mediated activation of procarcinogens to genotoxic metabolites by polycyclic aromatic hydrocarbons.
    Shimada T; Guengerich FP
    Chem Res Toxicol; 2006 Feb; 19(2):288-94. PubMed ID: 16485905
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Bioactivation of diesel exhaust particle extracts and their major nitrated polycyclic aromatic hydrocarbon components, 1-nitropyrene and dinitropyrenes, by human cytochromes P450 1A1, 1A2, and 1B1.
    Yamazaki H; Hatanaka N; Kizu R; Hayakawa K; Shimada N; Guengerich FP; Nakajima M; Yokoi T
    Mutat Res; 2000 Dec; 472(1-2):129-38. PubMed ID: 11113705
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of human cytochrome P450 1B1, 1A1 and 1A2 by antigenotoxic compounds, purpurin and alizarin.
    Takahashi E; Fujita K; Kamataki T; Arimoto-Kobayashi S; Okamoto K; Negishi T
    Mutat Res; 2002 Oct; 508(1-2):147-56. PubMed ID: 12379470
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Metabolic activation of polycyclic aromatic hydrocarbons and other procarcinogens by cytochromes P450 1A1 and P450 1B1 allelic variants and other human cytochromes P450 in Salmonella typhimurium NM2009.
    Shimada T; Oda Y; Gillam EM; Guengerich FP; Inoue K
    Drug Metab Dispos; 2001 Sep; 29(9):1176-82. PubMed ID: 11502724
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mutagenicity of cyclopenta-fused isomers of benz(a)anthracene in bacterial and rodent cells and identification of the major rat liver microsomal metabolites.
    Nesnow S; Leavitt S; Easterling R; Watts R; Toney SH; Claxton L; Sangaiah R; Toney GE; Wiley J; Fraher P
    Cancer Res; 1984 Nov; 44(11):4993-5003. PubMed ID: 6386146
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutagenicity of dibenz[a,c]anthracene and its derivatives in Salmonella typhimurium TA100.
    Kumar S; Kole PL; Sikka HC
    Mutat Res; 1990 Dec; 242(4):337-43. PubMed ID: 2255327
    [TBL] [Abstract][Full Text] [Related]  

  • 9. NTP Technical Report on the comparative toxicity studies of allyl acetate (CAS No. 591-87-7), allyl alcohol (CAS No. 107-18-6) and acrolein (CAS No. 107-02-8) administered by gavage to F344/N rats and B6C3F1 mice.
    Irwin RD
    Toxic Rep Ser; 2006 Jul; (48):1-73, A1-H10. PubMed ID: 17160105
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Potent mutagenicity of 3-methylindole requires pulmonary cytochrome P450-mediated bioactivation: a comparison to the prototype cigarette smoke mutagens B(a)P and NNK.
    Weems JM; Lamb JG; D'Agostino J; Ding X; Yost GS
    Chem Res Toxicol; 2010 Nov; 23(11):1682-90. PubMed ID: 20795680
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Rat hepatocyte-mediated bacterial mutagenicity in relation to the carcinogenic potency of benz(a)anthracene, benzo(a)pyrene, and twenty-five methylated derivatives.
    Utesch D; Glatt H; Oesch F
    Cancer Res; 1987 Mar; 47(6):1509-15. PubMed ID: 3545447
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Toxic effects of methylated benz[a]anthracenes in liver cells.
    Marvanová S; Vondrácek J; Penccíková K; Trilecová L; Krcmárr P; Topinka J; Nováková Z; Milcová A; Machala M
    Chem Res Toxicol; 2008 Feb; 21(2):503-12. PubMed ID: 18205319
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Nitrogen-substitution effects on the mutagenicity and cytochrome P450 isoform-selectivity of chrysene analogs.
    Yamada K; Hakura A; Kato TA; Mizutani T; Saeki K
    Mutat Res; 2005 Sep; 586(1):87-95. PubMed ID: 16087391
    [TBL] [Abstract][Full Text] [Related]  

  • 14. In vitro anti-mutagenic effect of magnolol against direct and indirect mutagens.
    Saito J; Sakai Y; Nagase H
    Mutat Res; 2006 Oct; 609(1):68-73. PubMed ID: 16884943
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Effect of chlorinated hydrocarbons on expression of cytochrome P450 1A1, 1A2 and 1B1 and 2- and 4-hydroxylation of 17beta-estradiol in female Sprague-Dawley rats.
    Badawi AF; Cavalieri EL; Rogan EG
    Carcinogenesis; 2000 Aug; 21(8):1593-9. PubMed ID: 10910964
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Enzymatic characterization of in vitro-expressed Baikal seal cytochrome P450 (CYP) 1A1, 1A2, and 1B1: implication of low metabolic potential of CYP1A2 uniquely evolved in aquatic mammals.
    Iwata H; Yamaguchi K; Takeshita Y; Kubota A; Hirakawa S; Isobe T; Hirano M; Kim EY
    Aquat Toxicol; 2015 May; 162():138-151. PubMed ID: 25814058
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The aryl hydrocarbon receptor-dependent deregulation of cell cycle control induced by polycyclic aromatic hydrocarbons in rat liver epithelial cells.
    Andrysík Z; Vondrácek J; Machala M; Krcmár P; Svihálková-Sindlerová L; Kranz A; Weiss C; Faust D; Kozubík A; Dietrich C
    Mutat Res; 2007 Feb; 615(1-2):87-97. PubMed ID: 17141280
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Characterization of the dose-response of CYP1B1, CYP1A1, and CYP1A2 in the liver of female Sprague-Dawley rats following chronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin.
    Walker NJ; Portier CJ; Lax SF; Crofts FG; Li Y; Lucier GW; Sutter TR
    Toxicol Appl Pharmacol; 1999 Feb; 154(3):279-86. PubMed ID: 9931287
    [TBL] [Abstract][Full Text] [Related]  

  • 19. NTP technical report on the toxicity and metabolism studies of chloral hydrate (CAS No. 302-17-0). Administered by gavage to F344/N rats and B6C3F1 mice.
    Beland FA
    Toxic Rep Ser; 1999 Aug; (59):1-66, A1-E7. PubMed ID: 11803702
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Induction of chromosomal aberrations in rat bone marrow cells and mutations in Salmonella typhimurium by benz[a]anthracene derivatives.
    Ito Y; Ueda N; Maeda S; Murao S; Sugiyama T; Lee H; Harvey RG
    Mutat Res; 1988 Sep; 206(1):55-63. PubMed ID: 3045537
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.