BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

260 related articles for article (PubMed ID: 21384849)

  • 1. Estimating toxicity-related biological pathway altering doses for high-throughput chemical risk assessment.
    Judson RS; Kavlock RJ; Setzer RW; Hubal EA; Martin MT; Knudsen TB; Houck KA; Thomas RS; Wetmore BA; Dix DJ
    Chem Res Toxicol; 2011 Apr; 24(4):451-62. PubMed ID: 21384849
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Integration of dosimetry, exposure, and high-throughput screening data in chemical toxicity assessment.
    Wetmore BA; Wambaugh JF; Ferguson SS; Sochaski MA; Rotroff DM; Freeman K; Clewell HJ; Dix DJ; Andersen ME; Houck KA; Allen B; Judson RS; Singh R; Kavlock RJ; Richard AM; Thomas RS
    Toxicol Sci; 2012 Jan; 125(1):157-74. PubMed ID: 21948869
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Incorporating population variability and susceptible subpopulations into dosimetry for high-throughput toxicity testing.
    Wetmore BA; Allen B; Clewell HJ; Parker T; Wambaugh JF; Almond LM; Sochaski MA; Thomas RS
    Toxicol Sci; 2014 Nov; 142(1):210-24. PubMed ID: 25145659
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Metabolism, variability and risk assessment.
    Dorne JL
    Toxicology; 2010 Feb; 268(3):156-64. PubMed ID: 19932147
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ethyl methanesulfonate toxicity in Viracept--a comprehensive human risk assessment based on threshold data for genotoxicity.
    Müller L; Gocke E; Lavé T; Pfister T
    Toxicol Lett; 2009 Nov; 190(3):317-29. PubMed ID: 19443141
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Implementing Toxicity Testing in the 21st Century (TT21C): Making safety decisions using toxicity pathways, and progress in a prototype risk assessment.
    Adeleye Y; Andersen M; Clewell R; Davies M; Dent M; Edwards S; Fowler P; Malcomber S; Nicol B; Scott A; Scott S; Sun B; Westmoreland C; White A; Zhang Q; Carmichael PL
    Toxicology; 2015 Jun; 332():102-11. PubMed ID: 24582757
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Advancing exposure characterization for chemical evaluation and risk assessment.
    Cohen Hubal EA; Richard A; Aylward L; Edwards S; Gallagher J; Goldsmith MR; Isukapalli S; Tornero-Velez R; Weber E; Kavlock R
    J Toxicol Environ Health B Crit Rev; 2010 Feb; 13(2-4):299-313. PubMed ID: 20574904
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Physiological-model-based derivation of the adult and child pharmacokinetic intraspecies uncertainty factors for volatile organic compounds.
    Pelekis M; Gephart LA; Lerman SE
    Regul Toxicol Pharmacol; 2001 Feb; 33(1):12-20. PubMed ID: 11259175
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Quantitative in vitro-to-in vivo extrapolation in a high-throughput environment.
    Wetmore BA
    Toxicology; 2015 Jun; 332():94-101. PubMed ID: 24907440
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Relative impact of incorporating pharmacokinetics on predicting in vivo hazard and mode of action from high-throughput in vitro toxicity assays.
    Wetmore BA; Wambaugh JF; Ferguson SS; Li L; Clewell HJ; Judson RS; Freeman K; Bao W; Sochaski MA; Chu TM; Black MB; Healy E; Allen B; Andersen ME; Wolfinger RD; Thomas RS
    Toxicol Sci; 2013 Apr; 132(2):327-46. PubMed ID: 23358191
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Chloroform mode of action: implications for cancer risk assessment.
    Golden RJ; Holm SE; Robinson DE; Julkunen PH; Reese EA
    Regul Toxicol Pharmacol; 1997 Oct; 26(2):142-55. PubMed ID: 9356278
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Computational toxicology as implemented by the U.S. EPA: providing high throughput decision support tools for screening and assessing chemical exposure, hazard and risk.
    Kavlock R; Dix D
    J Toxicol Environ Health B Crit Rev; 2010 Feb; 13(2-4):197-217. PubMed ID: 20574897
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Virtual tissues in toxicology.
    Shah I; Wambaugh J
    J Toxicol Environ Health B Crit Rev; 2010 Feb; 13(2-4):314-28. PubMed ID: 20574905
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Quantitative in vitro to in vivo extrapolation of cell-based toxicity assay results.
    Yoon M; Campbell JL; Andersen ME; Clewell HJ
    Crit Rev Toxicol; 2012 Sep; 42(8):633-52. PubMed ID: 22667820
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Impact of inter-individual differences in drug metabolism and pharmacokinetics on safety evaluation.
    Dorne JL
    Fundam Clin Pharmacol; 2004 Dec; 18(6):609-20. PubMed ID: 15548231
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Chemical-specific screening criteria for interpretation of biomonitoring data for volatile organic compounds (VOCs)--application of steady-state PBPK model solutions.
    Aylward LL; Kirman CR; Blount BC; Hays SM
    Regul Toxicol Pharmacol; 2010 Oct; 58(1):33-44. PubMed ID: 20685286
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Human variability in xenobiotic metabolism and pathway-related uncertainty factors for chemical risk assessment: a review.
    Dorne JL; Walton K; Renwick AG
    Food Chem Toxicol; 2005 Feb; 43(2):203-16. PubMed ID: 15621332
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cellular stress response pathway system as a sentinel ensemble in toxicological screening.
    Simmons SO; Fan CY; Ramabhadran R
    Toxicol Sci; 2009 Oct; 111(2):202-25. PubMed ID: 19567883
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Investigation of the potential impact of benchmark dose and pharmacokinetic modeling in noncancer risk assessment.
    Clewell HJ; Gentry PR; Gearhart JM
    J Toxicol Environ Health; 1997 Dec; 52(6):475-515. PubMed ID: 9397182
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Computational systems biology and dose-response modeling in relation to new directions in toxicity testing.
    Zhang Q; Bhattacharya S; Andersen ME; Conolly RB
    J Toxicol Environ Health B Crit Rev; 2010 Feb; 13(2-4):253-76. PubMed ID: 20574901
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.