BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

81 related articles for article (PubMed ID: 21385059)

  • 1. Heparanase modulation of early growth response gene expression.
    Yan X; Jin S; Li S; Gong F; Zhang D; Zhang X; Li JP
    Zoolog Sci; 2011 Mar; 28(3):189-94. PubMed ID: 21385059
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Molecular structure of heparan sulfate from Spalax. Implications of heparanase and hypoxia.
    Sandwall E; Bodevin S; Nasser NJ; Nevo E; Avivi A; Vlodavsky I; Li JP
    J Biol Chem; 2009 Feb; 284(6):3814-22. PubMed ID: 19068480
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Transgenic or tumor-induced expression of heparanase upregulates sulfation of heparan sulfate.
    Escobar Galvis ML; Jia J; Zhang X; Jastrebova N; Spillmann D; Gottfridsson E; van Kuppevelt TH; Zcharia E; Vlodavsky I; Lindahl U; Li JP
    Nat Chem Biol; 2007 Dec; 3(12):773-8. PubMed ID: 17952066
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Increased heparanase expression is caused by promoter hypomethylation and up-regulation of transcriptional factor early growth response-1 in human prostate cancer.
    Ogishima T; Shiina H; Breault JE; Tabatabai L; Bassett WW; Enokida H; Li LC; Kawakami T; Urakami S; Ribeiro-Filho LA; Terashima M; Fujime M; Igawa M; Dahiya R
    Clin Cancer Res; 2005 Feb; 11(3):1028-36. PubMed ID: 15709168
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Regulation, function and clinical significance of heparanase in cancer metastasis and angiogenesis.
    Ilan N; Elkin M; Vlodavsky I
    Int J Biochem Cell Biol; 2006; 38(12):2018-39. PubMed ID: 16901744
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Implications of heparan sulfate and heparanase in neuroinflammation.
    Zhang X; Wang B; Li JP
    Matrix Biol; 2014 Apr; 35():174-81. PubMed ID: 24398134
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Unexpected new roles for heparanase in Type 1 diabetes and immune gene regulation.
    Parish CR; Freeman C; Ziolkowski AF; He YQ; Sutcliffe EL; Zafar A; Rao S; Simeonovic CJ
    Matrix Biol; 2013 Jun; 32(5):228-33. PubMed ID: 23499527
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A functional heparan sulfate mimetic implicates both heparanase and heparan sulfate in tumor angiogenesis and invasion in a mouse model of multistage cancer.
    Joyce JA; Freeman C; Meyer-Morse N; Parish CR; Hanahan D
    Oncogene; 2005 Jun; 24(25):4037-51. PubMed ID: 15806157
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Transgenic expression of mammalian heparanase uncovers physiological functions of heparan sulfate in tissue morphogenesis, vascularization, and feeding behavior.
    Zcharia E; Metzger S; Chajek-Shaul T; Aingorn H; Elkin M; Friedmann Y; Weinstein T; Li JP; Lindahl U; Vlodavsky I
    FASEB J; 2004 Feb; 18(2):252-63. PubMed ID: 14769819
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Heparanase induces vascular endothelial growth factor expression: correlation with p38 phosphorylation levels and Src activation.
    Zetser A; Bashenko Y; Edovitsky E; Levy-Adam F; Vlodavsky I; Ilan N
    Cancer Res; 2006 Feb; 66(3):1455-63. PubMed ID: 16452201
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Overexpression of heparanase in mice promoted megakaryopoiesis.
    Tan YX; Cui H; Wan LM; Gong F; Zhang X; Vlodavsky I; Li JP
    Glycobiology; 2018 May; 28(5):269-275. PubMed ID: 29471321
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Heparanase is expressed in osteoblastic cells and stimulates bone formation and bone mass.
    Kram V; Zcharia E; Yacoby-Zeevi O; Metzger S; Chajek-Shaul T; Gabet Y; Müller R; Vlodavsky I; Bab I
    J Cell Physiol; 2006 Jun; 207(3):784-92. PubMed ID: 16514606
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Promoter CpG hypomethylation and transcription factor EGR1 hyperactivate heparanase expression in bladder cancer.
    Ogishima T; Shiina H; Breault JE; Terashima M; Honda S; Enokida H; Urakami S; Tokizane T; Kawakami T; Ribeiro-Filho LA; Fujime M; Kane CJ; Carroll PR; Igawa M; Dahiya R
    Oncogene; 2005 Oct; 24(45):6765-72. PubMed ID: 16007175
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Expression of Ext1, Ext2, and heparanase genes in brain of senescence-accelerated OXYS rats in early ontogenesis and during development of neurodegenerative changes.
    Shevelev OB; Rykova VI; Fedoseeva LA; Leberfarb EY; Dymshits GM; Kolosova NG
    Biochemistry (Mosc); 2012 Jan; 77(1):56-61. PubMed ID: 22339633
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Heparanase gene silencing, tumor invasiveness, angiogenesis, and metastasis.
    Edovitsky E; Elkin M; Zcharia E; Peretz T; Vlodavsky I
    J Natl Cancer Inst; 2004 Aug; 96(16):1219-30. PubMed ID: 15316057
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mammalian heparanase as mediator of tumor metastasis and angiogenesis.
    Vlodavsky I; Elkin M; Pappo O; Aingorn H; Atzmon R; Ishai-Michaeli R; Aviv A; Pecker I; Friedmann Y
    Isr Med Assoc J; 2000 Jul; 2 Suppl():37-45. PubMed ID: 10909416
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Regulation of heparanase gene expression by estrogen in breast cancer.
    Elkin M; Cohen I; Zcharia E; Orgel A; Guatta-Rangini Z; Peretz T; Vlodavsky I; Kleinman HK
    Cancer Res; 2003 Dec; 63(24):8821-6. PubMed ID: 14695198
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Heparanase induces tissue factor pathway inhibitor expression and extracellular accumulation in endothelial and tumor cells.
    Nadir Y; Brenner B; Gingis-Velitski S; Levy-Adam F; Ilan N; Zcharia E; Nadir E; Vlodavsky I
    Thromb Haemost; 2008 Jan; 99(1):133-41. PubMed ID: 18217145
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Expression of the heparan sulfate-degrading enzyme heparanase is induced in infiltrating CD4+ T cells in experimental autoimmune encephalomyelitis and regulated at the level of transcription by early growth response gene 1.
    de Mestre AM; Staykova MA; Hornby JR; Willenborg DO; Hulett MD
    J Leukoc Biol; 2007 Nov; 82(5):1289-300. PubMed ID: 17656651
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Heparanase is essential for the development of diabetic nephropathy in mice.
    Gil N; Goldberg R; Neuman T; Garsen M; Zcharia E; Rubinstein AM; van Kuppevelt T; Meirovitz A; Pisano C; Li JP; van der Vlag J; Vlodavsky I; Elkin M
    Diabetes; 2012 Jan; 61(1):208-16. PubMed ID: 22106160
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.