310 related articles for article (PubMed ID: 21385376)
1. Endosomal accumulation of APP in wobbler motor neurons reflects impaired vesicle trafficking: implications for human motor neuron disease.
Palmisano R; Golfi P; Heimann P; Shaw C; Troakes C; Schmitt-John T; Bartsch JW
BMC Neurosci; 2011 Mar; 12():24. PubMed ID: 21385376
[TBL] [Abstract][Full Text] [Related]
2. Neuroprotective effects of the Sigma-1 receptor (S1R) agonist PRE-084, in a mouse model of motor neuron disease not linked to SOD1 mutation.
Peviani M; Salvaneschi E; Bontempi L; Petese A; Manzo A; Rossi D; Salmona M; Collina S; Bigini P; Curti D
Neurobiol Dis; 2014 Feb; 62():218-32. PubMed ID: 24141020
[TBL] [Abstract][Full Text] [Related]
3. Motor neuron disease occurring in a mutant dynactin mouse model is characterized by defects in vesicular trafficking.
Laird FM; Farah MH; Ackerley S; Hoke A; Maragakis N; Rothstein JD; Griffin J; Price DL; Martin LJ; Wong PC
J Neurosci; 2008 Feb; 28(9):1997-2005. PubMed ID: 18305234
[TBL] [Abstract][Full Text] [Related]
4. Neurofilaments and orthograde transport are reduced in ventral root axons of transgenic mice that express human SOD1 with a G93A mutation.
Zhang B; Tu P; Abtahian F; Trojanowski JQ; Lee VM
J Cell Biol; 1997 Dec; 139(5):1307-15. PubMed ID: 9382875
[TBL] [Abstract][Full Text] [Related]
5. The Golgi apparatus of spinal cord motor neurons in transgenic mice expressing mutant Cu,Zn superoxide dismutase becomes fragmented in early, preclinical stages of the disease.
Mourelatos Z; Gonatas NK; Stieber A; Gurney ME; Dal Canto MC
Proc Natl Acad Sci U S A; 1996 May; 93(11):5472-7. PubMed ID: 8643599
[TBL] [Abstract][Full Text] [Related]
6. Amyloid precursor protein (APP) contributes to pathology in the SOD1(G93A) mouse model of amyotrophic lateral sclerosis.
Bryson JB; Hobbs C; Parsons MJ; Bosch KD; Pandraud A; Walsh FS; Doherty P; Greensmith L
Hum Mol Genet; 2012 Sep; 21(17):3871-82. PubMed ID: 22678056
[TBL] [Abstract][Full Text] [Related]
7. Human Cu/Zn superoxide dismutase (SOD1) overexpression in mice causes mitochondrial vacuolization, axonal degeneration, and premature motoneuron death and accelerates motoneuron disease in mice expressing a familial amyotrophic lateral sclerosis mutant SOD1.
Jaarsma D; Haasdijk ED; Grashorn JA; Hawkins R; van Duijn W; Verspaget HW; London J; Holstege JC
Neurobiol Dis; 2000 Dec; 7(6 Pt B):623-43. PubMed ID: 11114261
[TBL] [Abstract][Full Text] [Related]
8. In vivo quantification of spinal and bulbar motor neuron degeneration in the G93A-SOD1 transgenic mouse model of ALS by T2 relaxation time and apparent diffusion coefficient.
Niessen HG; Angenstein F; Sander K; Kunz WS; Teuchert M; Ludolph AC; Heinze HJ; Scheich H; Vielhaber S
Exp Neurol; 2006 Oct; 201(2):293-300. PubMed ID: 16740261
[TBL] [Abstract][Full Text] [Related]
9. Mutant SOD1G93A triggers mitochondrial fragmentation in spinal cord motor neurons: neuroprotection by SIRT3 and PGC-1α.
Song W; Song Y; Kincaid B; Bossy B; Bossy-Wetzel E
Neurobiol Dis; 2013 Mar; 51():72-81. PubMed ID: 22819776
[TBL] [Abstract][Full Text] [Related]
10. The neuronal Golgi apparatus is fragmented in transgenic mice expressing a mutant human SOD1, but not in mice expressing the human NF-H gene.
Stieber A; Gonatas JO; Collard J; Meier J; Julien J; Schweitzer P; Gonatas NK
J Neurol Sci; 2000 Feb; 173(1):63-72. PubMed ID: 10675581
[TBL] [Abstract][Full Text] [Related]
11. Histological evidence of protein aggregation in mutant SOD1 transgenic mice and in amyotrophic lateral sclerosis neural tissues.
Watanabe M; Dykes-Hoberg M; Culotta VC; Price DL; Wong PC; Rothstein JD
Neurobiol Dis; 2001 Dec; 8(6):933-41. PubMed ID: 11741389
[TBL] [Abstract][Full Text] [Related]
12. The neuroprotective factor Wlds does not attenuate mutant SOD1-mediated motor neuron disease.
Vande Velde C; Garcia ML; Yin X; Trapp BD; Cleveland DW
Neuromolecular Med; 2004; 5(3):193-203. PubMed ID: 15626820
[TBL] [Abstract][Full Text] [Related]
13. Nuclear localization of human SOD1 and mutant SOD1-specific disruption of survival motor neuron protein complex in transgenic amyotrophic lateral sclerosis mice.
Gertz B; Wong M; Martin LJ
J Neuropathol Exp Neurol; 2012 Feb; 71(2):162-77. PubMed ID: 22249462
[TBL] [Abstract][Full Text] [Related]
14. Overexpression of Abeta is associated with acceleration of onset of motor impairment and superoxide dismutase 1 aggregation in an amyotrophic lateral sclerosis mouse model.
Li QX; Mok SS; Laughton KM; McLean CA; Volitakis I; Cherny RA; Cheung NS; White AR; Masters CL
Aging Cell; 2006 Apr; 5(2):153-65. PubMed ID: 16626394
[TBL] [Abstract][Full Text] [Related]
15. Galectin-1 deficiency improves axonal swelling of motor neurones in SOD1(G93A) transgenic mice.
Kobayakawa Y; Sakumi K; Kajitani K; Kadoya T; Horie H; Kira J; Nakabeppu Y
Neuropathol Appl Neurobiol; 2015 Feb; 41(2):227-44. PubMed ID: 24707896
[TBL] [Abstract][Full Text] [Related]
16. Inducible nitric oxide synthase is present in motor neuron mitochondria and Schwann cells and contributes to disease mechanisms in ALS mice.
Chen K; Northington FJ; Martin LJ
Brain Struct Funct; 2010 Mar; 214(2-3):219-34. PubMed ID: 19888600
[TBL] [Abstract][Full Text] [Related]
17. Protein-bound crotonaldehyde accumulates in the spinal cord of superoxide dismutase-1 mutation-associated familial amyotrophic lateral sclerosis and its transgenic mouse model.
Shibata N; Kawaguchi M; Uchida K; Kakita A; Takahashi H; Nakano R; Fujimura H; Sakoda S; Ihara Y; Nobukuni K; Takehisa Y; Kuroda S; Kokubo Y; Kuzuhara S; Honma T; Mochizuki Y; Mizutani T; Yamada S; Toi S; Sasaki S; Iwata M; Hirano A; Yamamoto T; Kato Y; Sawada T; Kobayashi M
Neuropathology; 2007 Feb; 27(1):49-61. PubMed ID: 17319283
[TBL] [Abstract][Full Text] [Related]
18. The Overexpression of TDP-43 Protein in the Neuron and Oligodendrocyte Cells Causes the Progressive Motor Neuron Degeneration in the SOD1 G93A Transgenic Mouse Model of Amyotrophic Lateral Sclerosis.
Lu Y; Tang C; Zhu L; Li J; Liang H; Zhang J; Xu R
Int J Biol Sci; 2016; 12(9):1140-9. PubMed ID: 27570488
[TBL] [Abstract][Full Text] [Related]
19. Widespread aggregation of mutant VAPB associated with ALS does not cause motor neuron degeneration or modulate mutant SOD1 aggregation and toxicity in mice.
Qiu L; Qiao T; Beers M; Tan W; Wang H; Yang B; Xu Z
Mol Neurodegener; 2013 Jan; 8():1. PubMed ID: 23281774
[TBL] [Abstract][Full Text] [Related]
20. Neuregulin 1 confers neuroprotection in SOD1-linked amyotrophic lateral sclerosis mice via restoration of C-boutons of spinal motor neurons.
Lasiene J; Komine O; Fujimori-Tonou N; Powers B; Endo F; Watanabe S; Shijie J; Ravits J; Horner P; Misawa H; Yamanaka K
Acta Neuropathol Commun; 2016 Feb; 4():15. PubMed ID: 26891847
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]