BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

236 related articles for article (PubMed ID: 21385869)

  • 1. An N-terminal polybasic domain and cell surface localization are required for mutant prion protein toxicity.
    Solomon IH; Khatri N; Biasini E; Massignan T; Huettner JE; Harris DA
    J Biol Chem; 2011 Apr; 286(16):14724-36. PubMed ID: 21385869
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ion channels induced by the prion protein: mediators of neurotoxicity.
    Solomon IH; Biasini E; Harris DA
    Prion; 2012; 6(1):40-5. PubMed ID: 22453177
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The N-Terminal Polybasic Region of Prion Protein Is Crucial in Prion Pathogenesis Independently of the Octapeptide Repeat Region.
    Das NR; Miyata H; Hara H; Chida J; Uchiyama K; Masujin K; Watanabe H; Kondoh G; Sakaguchi S
    Mol Neurobiol; 2020 Feb; 57(2):1203-1216. PubMed ID: 31707632
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Dissociation of infectivity from seeding ability in prions with alternate docking mechanism.
    Miller MB; Geoghegan JC; Supattapone S
    PLoS Pathog; 2011 Jul; 7(7):e1002128. PubMed ID: 21779169
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Prion neurotoxicity: insights from prion protein mutants.
    Solomon IH; Schepker JA; Harris DA
    Curr Issues Mol Biol; 2010; 12(2):51-61. PubMed ID: 19767650
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mutated but Not Deleted Ovine PrP(C) N-Terminal Polybasic Region Strongly Interferes with Prion Propagation in Transgenic Mice.
    Khalifé M; Reine F; Paquet-Fifield S; Castille J; Herzog L; Vilotte M; Moudjou M; Moazami-Goudarzi K; Makhzami S; Passet B; Andréoletti O; Vilette D; Laude H; Béringue V; Vilotte JL
    J Virol; 2016 Feb; 90(3):1638-46. PubMed ID: 26608316
    [TBL] [Abstract][Full Text] [Related]  

  • 7. N-Terminal Regions of Prion Protein: Functions and Roles in Prion Diseases.
    Hara H; Sakaguchi S
    Int J Mol Sci; 2020 Aug; 21(17):. PubMed ID: 32872280
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A seven-residue deletion in PrP leads to generation of a spontaneous prion formed from C-terminal C1 fragment of PrP.
    Munoz-Montesino C; Larkem D; Barbereau C; Igel-Egalon A; Truchet S; Jacquet E; Nhiri N; Moudjou M; Sizun C; Rezaei H; Béringue V; Dron M
    J Biol Chem; 2020 Oct; 295(41):14025-14039. PubMed ID: 32788216
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effects of prion protein devoid of the N-terminal residues 25-50 on prion pathogenesis in mice.
    Das NR; Miyata H; Hara H; Uchiyama K; Chida J; Yano M; Watanabe H; Kondoh G; Sakaguchi S
    Arch Virol; 2017 Jul; 162(7):1867-1876. PubMed ID: 28255815
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Selective processing and metabolism of disease-causing mutant prion proteins.
    Ashok A; Hegde RS
    PLoS Pathog; 2009 Jun; 5(6):e1000479. PubMed ID: 19543376
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The N-terminal, polybasic region is critical for prion protein neuroprotective activity.
    Turnbaugh JA; Westergard L; Unterberger U; Biasini E; Harris DA
    PLoS One; 2011; 6(9):e25675. PubMed ID: 21980526
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cellular phenotyping of secretory and nuclear prion proteins associated with inherited prion diseases.
    Lorenz H; Windl O; Kretzschmar HA
    J Biol Chem; 2002 Mar; 277(10):8508-16. PubMed ID: 11756421
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mouse prion protein (PrP) segment 100 to 104 regulates conversion of PrP(C) to PrP(Sc) in prion-infected neuroblastoma cells.
    Hara H; Okemoto-Nakamura Y; Shinkai-Ouchi F; Hanada K; Yamakawa Y; Hagiwara K
    J Virol; 2012 May; 86(10):5626-36. PubMed ID: 22398286
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Neurotoxic mutants of the prion protein induce spontaneous ionic currents in cultured cells.
    Solomon IH; Huettner JE; Harris DA
    J Biol Chem; 2010 Aug; 285(34):26719-26. PubMed ID: 20573963
    [TBL] [Abstract][Full Text] [Related]  

  • 15. An inter-domain regulatory mechanism controls toxic activities of PrP
    McDonald AJ; Wu B; Harris DA
    Prion; 2017 Nov; 11(6):388-397. PubMed ID: 28960140
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mechanisms of prion-induced modifications in membrane transport properties: implications for signal transduction and neurotoxicity.
    Kourie JI
    Chem Biol Interact; 2001 Oct; 138(1):1-26. PubMed ID: 11640912
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The N-terminal, polybasic region of PrP(C) dictates the efficiency of prion propagation by binding to PrP(Sc).
    Turnbaugh JA; Unterberger U; Saá P; Massignan T; Fluharty BR; Bowman FP; Miller MB; Supattapone S; Biasini E; Harris DA
    J Neurosci; 2012 Jun; 32(26):8817-30. PubMed ID: 22745483
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A novel, drug-based, cellular assay for the activity of neurotoxic mutants of the prion protein.
    Massignan T; Stewart RS; Biasini E; Solomon IH; Bonetto V; Chiesa R; Harris DA
    J Biol Chem; 2010 Mar; 285(10):7752-65. PubMed ID: 19940127
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Generating Bona Fide Mammalian Prions with Internal Deletions.
    Munoz-Montesino C; Sizun C; Moudjou M; Herzog L; Reine F; Chapuis J; Ciric D; Igel-Egalon A; Laude H; Béringue V; Rezaei H; Dron M
    J Virol; 2016 Aug; 90(15):6963-6975. PubMed ID: 27226369
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Prion Protein Devoid of the Octapeptide Repeat Region Delays Bovine Spongiform Encephalopathy Pathogenesis in Mice.
    Hara H; Miyata H; Das NR; Chida J; Yoshimochi T; Uchiyama K; Watanabe H; Kondoh G; Yokoyama T; Sakaguchi S
    J Virol; 2018 Jan; 92(1):. PubMed ID: 29046443
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.