BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

233 related articles for article (PubMed ID: 21386095)

  • 1. Vav1-mediated scaffolding interactions stabilize SLP-76 microclusters and contribute to antigen-dependent T cell responses.
    Sylvain NR; Nguyen K; Bunnell SC
    Sci Signal; 2011 Mar; 4(163):ra14. PubMed ID: 21386095
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Studying the dynamics of SLP-76, Nck, and Vav1 multimolecular complex formation in live human cells with triple-color FRET.
    Pauker MH; Hassan N; Noy E; Reicher B; Barda-Saad M
    Sci Signal; 2012 Apr; 5(221):rs3. PubMed ID: 22534133
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Complementary phosphorylation sites in the adaptor protein SLP-76 promote synergistic activation of natural killer cells.
    Kim HS; Long EO
    Sci Signal; 2012 Jul; 5(232):ra49. PubMed ID: 22786724
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cooperative interactions at the SLP-76 complex are critical for actin polymerization.
    Barda-Saad M; Shirasu N; Pauker MH; Hassan N; Perl O; Balbo A; Yamaguchi H; Houtman JC; Appella E; Schuck P; Samelson LE
    EMBO J; 2010 Jul; 29(14):2315-28. PubMed ID: 20562827
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The N-terminal 20-amino acid region of guanine nucleotide exchange factor Vav1 plays a distinguished role in T cell receptor-mediated calcium signaling.
    Li SY; Du MJ; Wan YJ; Lan B; Liu YH; Yang Y; Zhang CZ; Cao Y
    J Biol Chem; 2013 Feb; 288(6):3777-85. PubMed ID: 23271736
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Src homology 2 domain-containing leukocyte phosphoprotein of 76 kDa and phospholipase C gamma 1 are required for NF-kappa B activation and lipid raft recruitment of protein kinase C theta induced by T cell costimulation.
    Dienz O; Möller A; Strecker A; Stephan N; Krammer PH; Dröge W; Schmitz ML
    J Immunol; 2003 Jan; 170(1):365-72. PubMed ID: 12496421
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The chemokine CXCL12 generates costimulatory signals in T cells to enhance phosphorylation and clustering of the adaptor protein SLP-76.
    Smith X; Schneider H; Köhler K; Liu H; Lu Y; Rudd CE
    Sci Signal; 2013 Jul; 6(286):ra65. PubMed ID: 23901140
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Vav2 activates c-fos serum response element and CD69 expression but negatively regulates nuclear factor of activated T cells and interleukin-2 gene activation in T lymphocyte.
    Tartare-Deckert S; Monthouel MN; Charvet C; Foucault I; Van Obberghen E; Bernard A; Altman A; Deckert M
    J Biol Chem; 2001 Jun; 276(24):20849-57. PubMed ID: 11262396
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Signaling of the ITK (interleukin 2-inducible T cell kinase)-SYK (spleen tyrosine kinase) fusion kinase is dependent on adapter SLP-76 and on the adapter function of the kinases SYK and ZAP70.
    Hussain A; Mohammad DK; Gustafsson MO; Uslu M; Hamasy A; Nore BF; Mohamed AJ; Smith CI
    J Biol Chem; 2013 Mar; 288(10):7338-50. PubMed ID: 23293025
    [TBL] [Abstract][Full Text] [Related]  

  • 10. ADAP is an upstream regulator that precedes SLP-76 at sites of TCR engagement and stabilizes signaling microclusters.
    Lewis JB; Scangarello FA; Murphy JM; Eidell KP; Sodipo MO; Ophir MJ; Sargeant R; Seminario MC; Bunnell SC
    J Cell Sci; 2018 Nov; 131(21):. PubMed ID: 30305305
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Roles of the proline-rich domain in SLP-76 subcellular localization and T cell function.
    Singer AL; Bunnell SC; Obstfeld AE; Jordan MS; Wu JN; Myung PS; Samelson LE; Koretzky GA
    J Biol Chem; 2004 Apr; 279(15):15481-90. PubMed ID: 14722089
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cbl enforces Vav1 dependence and a restricted pathway of T cell development.
    Chiang J; Hodes RJ
    PLoS One; 2011 Apr; 6(4):e18542. PubMed ID: 21490975
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Activated Cdc42-associated kinase 1 (ACK1) binds the sterile α motif (SAM) domain of the adaptor SLP-76 and phosphorylates proximal tyrosines.
    Thaker YR; Recino A; Raab M; Jabeen A; Wallberg M; Fernandez N; Rudd CE
    J Biol Chem; 2017 Apr; 292(15):6281-6290. PubMed ID: 28188290
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A 10-aa-long sequence in SLP-76 upstream of the Gads binding site is essential for T cell development and function.
    Kumar L; Feske S; Rao A; Geha RS
    Proc Natl Acad Sci U S A; 2005 Dec; 102(52):19063-8. PubMed ID: 16354835
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Vav1 acidic region tyrosine 174 is required for the formation of T cell receptor-induced microclusters and is essential in T cell development and activation.
    Miletic AV; Sakata-Sogawa K; Hiroshima M; Hamann MJ; Gomez TS; Ota N; Kloeppel T; Kanagawa O; Tokunaga M; Billadeau DD; Swat W
    J Biol Chem; 2006 Dec; 281(50):38257-65. PubMed ID: 17050525
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The calponin homology domain of Vav1 associates with calmodulin and is prerequisite to T cell antigen receptor-induced calcium release in Jurkat T lymphocytes.
    Zhou Z; Yin J; Dou Z; Tang J; Zhang C; Cao Y
    J Biol Chem; 2007 Aug; 282(32):23737-44. PubMed ID: 17550897
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Multipoint binding of the SLP-76 SH2 domain to ADAP is critical for oligomerization of SLP-76 signaling complexes in stimulated T cells.
    Coussens NP; Hayashi R; Brown PH; Balagopalan L; Balbo A; Akpan I; Houtman JC; Barr VA; Schuck P; Appella E; Samelson LE
    Mol Cell Biol; 2013 Nov; 33(21):4140-51. PubMed ID: 23979596
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Membrane localization and function of Vav3 in T cells depend on its association with the adapter SLP-76.
    Charvet C; Canonigo AJ; Billadeau DD; Altman A
    J Biol Chem; 2005 Apr; 280(15):15289-99. PubMed ID: 15708849
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Vav2 lacks Ca
    Fray MA; Charpentier JC; Sylvain NR; Seminario MC; Bunnell SC
    J Cell Sci; 2020 Mar; 133(5):. PubMed ID: 31974114
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A guanine nucleotide exchange factor-independent function of Vav1 in transcriptional activation.
    Kuhne MR; Ku G; Weiss A
    J Biol Chem; 2000 Jan; 275(3):2185-90. PubMed ID: 10636924
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.