263 related articles for article (PubMed ID: 21389259)
1. Cardiopulmonary function in two human disorders of the hypoxia-inducible factor (HIF) pathway: von Hippel-Lindau disease and HIF-2alpha gain-of-function mutation.
Formenti F; Beer PA; Croft QP; Dorrington KL; Gale DP; Lappin TR; Lucas GS; Maher ER; Maxwell PH; McMullin MF; O'Connor DF; Percy MJ; Pugh CW; Ratcliffe PJ; Smith TG; Talbot NP; Robbins PA
FASEB J; 2011 Jun; 25(6):2001-11. PubMed ID: 21389259
[TBL] [Abstract][Full Text] [Related]
2. Mutation of von Hippel-Lindau tumour suppressor and human cardiopulmonary physiology.
Smith TG; Brooks JT; Balanos GM; Lappin TR; Layton DM; Leedham DL; Liu C; Maxwell PH; McMullin MF; McNamara CJ; Percy MJ; Pugh CW; Ratcliffe PJ; Talbot NP; Treacy M; Robbins PA
PLoS Med; 2006 Jul; 3(7):e290. PubMed ID: 16768548
[TBL] [Abstract][Full Text] [Related]
3. Up-regulation of hypoxia-inducible factors HIF-1alpha and HIF-2alpha under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function.
Krieg M; Haas R; Brauch H; Acker T; Flamme I; Plate KH
Oncogene; 2000 Nov; 19(48):5435-43. PubMed ID: 11114720
[TBL] [Abstract][Full Text] [Related]
4. The von Hippel-Lindau Chuvash mutation promotes pulmonary hypertension and fibrosis in mice.
Hickey MM; Richardson T; Wang T; Mosqueira M; Arguiri E; Yu H; Yu QC; Solomides CC; Morrisey EE; Khurana TS; Christofidou-Solomidou M; Simon MC
J Clin Invest; 2010 Mar; 120(3):827-39. PubMed ID: 20197624
[TBL] [Abstract][Full Text] [Related]
5. von Hippel-Lindau mutation in mice recapitulates Chuvash polycythemia via hypoxia-inducible factor-2alpha signaling and splenic erythropoiesis.
Hickey MM; Lam JC; Bezman NA; Rathmell WK; Simon MC
J Clin Invest; 2007 Dec; 117(12):3879-89. PubMed ID: 17992257
[TBL] [Abstract][Full Text] [Related]
6. [The expression of hypoxia inducible factor-1,2 alpha in sporadic clear cell renal cell carcinoma and their relationships to the mutations of von Hippel-Lindau gene].
Gong K; Zhang N; Na X; Wu G; Yang XY; Xin DQ; Na YQ
Zhonghua Wai Ke Za Zhi; 2005 Mar; 43(6):390-3. PubMed ID: 15854350
[TBL] [Abstract][Full Text] [Related]
7. Mutation of the von Hippel-Lindau gene alters human cardiopulmonary physiology.
Smith TG; Brooks JT; Balanos GM; Lappin TR; Layton DM; Leedham DL; Liu C; Maxwell PH; McMullin MF; McNamara CJ; Percy MJ; Pugh CW; Ratcliffe PJ; Talbot NP; Treacy M; Robbins PA
Adv Exp Med Biol; 2008; 605():51-6. PubMed ID: 18085246
[TBL] [Abstract][Full Text] [Related]
8. The relationship of erythropoietin overexpression with von Hippel-Lindau tumour suppressor gene mutations between hypoxia-inducible factor-1α and -2α in sporadic clear cell renal carcinoma.
Gong K; Zhang N; Zhang K; Na Y
Int J Mol Med; 2010 Dec; 26(6):907-12. PubMed ID: 21042786
[TBL] [Abstract][Full Text] [Related]
9. Pancreatic endocrine microadenomatosis in patients with von Hippel-Lindau disease: characterization by VHL/HIF pathway proteins expression.
Périgny M; Hammel P; Corcos O; Larochelle O; Giraud S; Richard S; Sauvanet A; Belghiti J; Ruszniewski P; Bedossa P; Couvelard A
Am J Surg Pathol; 2009 May; 33(5):739-48. PubMed ID: 19238077
[TBL] [Abstract][Full Text] [Related]
10. Expression of hypoxia-inducible factor 1alpha, hypoxia-inducible factor 2alpha, and von Hippel-Lindau protein in epithelial ovarian neoplasms and allelic loss of von Hippel-Lindau gene: nuclear expression of hypoxia-inducible factor 1alpha is an independent prognostic factor in ovarian carcinoma.
Osada R; Horiuchi A; Kikuchi N; Yoshida J; Hayashi A; Ota M; Katsuyama Y; Melillo G; Konishi I
Hum Pathol; 2007 Sep; 38(9):1310-20. PubMed ID: 17555795
[TBL] [Abstract][Full Text] [Related]
11. Therapeutic inhibition of HIF-2α reverses polycythemia and pulmonary hypertension in murine models of human diseases.
Ghosh MC; Zhang DL; Ollivierre WH; Noguchi A; Springer DA; Linehan WM; Rouault TA
Blood; 2021 May; 137(18):2509-2519. PubMed ID: 33512384
[TBL] [Abstract][Full Text] [Related]
12. Endolymphatic sac tumors in patients with and without von Hippel-Lindau disease: the role of genetic mutation, von Hippel-Lindau protein, and hypoxia inducible factor-1alpha expression.
Jensen RL; Gillespie D; House P; Layfield L; Shelton C
J Neurosurg; 2004 Mar; 100(3):488-97. PubMed ID: 15035285
[TBL] [Abstract][Full Text] [Related]
13. Mutations of von Hippel-Lindau tumor-suppressor gene and congenital polycythemia.
Pastore Y; Jedlickova K; Guan Y; Liu E; Fahner J; Hasle H; Prchal JF; Prchal JT
Am J Hum Genet; 2003 Aug; 73(2):412-9. PubMed ID: 12844285
[TBL] [Abstract][Full Text] [Related]
14. Congenital disorder of oxygen sensing: association of the homozygous Chuvash polycythemia VHL mutation with thrombosis and vascular abnormalities but not tumors.
Gordeuk VR; Sergueeva AI; Miasnikova GY; Okhotin D; Voloshin Y; Choyke PL; Butman JA; Jedlickova K; Prchal JT; Polyakova LA
Blood; 2004 May; 103(10):3924-32. PubMed ID: 14726398
[TBL] [Abstract][Full Text] [Related]
15. Involvement of oxygen-sensing pathways in physiologic and pathologic erythropoiesis.
Semenza GL
Blood; 2009 Sep; 114(10):2015-9. PubMed ID: 19494350
[TBL] [Abstract][Full Text] [Related]
16. Emetine promotes von Hippel-Lindau-independent degradation of hypoxia-inducible factor-2α in clear cell renal carcinoma.
Kong HS; Lee S; Beebe K; Scroggins B; Gupta G; Lee MJ; Jung YJ; Trepel J; Neckers L
Mol Pharmacol; 2010 Dec; 78(6):1072-8. PubMed ID: 20813864
[TBL] [Abstract][Full Text] [Related]
17. Iron deficiency modifies gene expression variation induced by augmented hypoxia sensing.
Zhang X; Zhang W; Ma SF; Miasniakova G; Sergueeva A; Ammosova T; Xu M; Nekhai S; Nourai M; Wade MS; Prchal JT; Garcia JGN; Machado RF; Gordeuk VR
Blood Cells Mol Dis; 2014 Jan; 52(1):35-45. PubMed ID: 23993337
[TBL] [Abstract][Full Text] [Related]
18. PTEN suppression of YY1 induces HIF-2 activity in von-Hippel-Lindau-null renal-cell carcinoma.
Petrella BL; Brinckerhoff CE
Cancer Biol Ther; 2009 Jul; 8(14):1389-401. PubMed ID: 19483472
[TBL] [Abstract][Full Text] [Related]
19. Contrasting effects on HIF-1alpha regulation by disease-causing pVHL mutations correlate with patterns of tumourigenesis in von Hippel-Lindau disease.
Clifford SC; Cockman ME; Smallwood AC; Mole DR; Woodward ER; Maxwell PH; Ratcliffe PJ; Maher ER
Hum Mol Genet; 2001 May; 10(10):1029-38. PubMed ID: 11331613
[TBL] [Abstract][Full Text] [Related]
20. VHL gene methylation contributes to excessive erythrocytosis in chronic mountain sickness rat model by upregulating the HIF-2α/EPO pathway.
Yang M; Zhu M; Song K; Wuren T; Yan J; Ge RL; Ji L; Cui S
Life Sci; 2021 Feb; 266():118873. PubMed ID: 33309718
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
