BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

173 related articles for article (PubMed ID: 21391903)

  • 1. Pharmaceutical reactivation of p53 pathways in cancer.
    Azmi AS
    Curr Pharm Des; 2011; 17(6):534-5. PubMed ID: 21391903
    [No Abstract]   [Full Text] [Related]  

  • 2. Fortifying p53 - beyond Mdm2 inhibitors.
    Sriraman A; Li Y; Dobbelstein M
    Aging (Albany NY); 2016 Sep; 8(9):1836-1837. PubMed ID: 27688014
    [No Abstract]   [Full Text] [Related]  

  • 3. Peptide activators of the p53 tumor suppressor.
    Zhan C; Lu W
    Curr Pharm Des; 2011; 17(6):603-9. PubMed ID: 21391910
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Reactivation of p53 gene by MDM2 inhibitors: A novel therapy for cancer treatment.
    Gupta A; Shah K; Oza MJ; Behl T
    Biomed Pharmacother; 2019 Jan; 109():484-492. PubMed ID: 30551517
    [TBL] [Abstract][Full Text] [Related]  

  • 5. MDM2 oligomers: antagonizers of the guardian of the genome.
    Leslie PL; Zhang Y
    Oncogene; 2016 Dec; 35(48):6157-6165. PubMed ID: 27041565
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The role of p53 in cancer drug resistance and targeted chemotherapy.
    Hientz K; Mohr A; Bhakta-Guha D; Efferth T
    Oncotarget; 2017 Jan; 8(5):8921-8946. PubMed ID: 27888811
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Reactivation of p53 by inhibiting Mdm2 E3 ligase: a novel antitumor approach.
    Di J; Zhang Y; Zheng J
    Curr Cancer Drug Targets; 2011 Oct; 11(8):987-94. PubMed ID: 21762075
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Patented inhibitors of p53-Mdm2 interaction (2006 - 2008).
    Weber L
    Expert Opin Ther Pat; 2010 Feb; 20(2):179-91. PubMed ID: 20100001
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Resistance acquisition to MDM2 inhibitors.
    Cinatl J; Speidel D; Hardcastle I; Michaelis M
    Biochem Soc Trans; 2014 Aug; 42(4):752-7. PubMed ID: 25109953
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Oncology. Recruiting the cell's own guardian for cancer therapy.
    Marx J
    Science; 2007 Mar; 315(5816):1211-3. PubMed ID: 17332387
    [No Abstract]   [Full Text] [Related]  

  • 11. Small-molecule inhibitors of p53-MDM2 interaction: the 2006-2010 update.
    Millard M; Pathania D; Grande F; Xu S; Neamati N
    Curr Pharm Des; 2011; 17(6):536-59. PubMed ID: 21391905
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Resistance mechanisms to inhibitors of p53-MDM2 interactions in cancer therapy: can we overcome them?
    Haronikova L; Bonczek O; Zatloukalova P; Kokas-Zavadil F; Kucerikova M; Coates PJ; Fahraeus R; Vojtesek B
    Cell Mol Biol Lett; 2021 Dec; 26(1):53. PubMed ID: 34911439
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Small molecule agents targeting the p53-MDM2 pathway for cancer therapy.
    Wang W; Hu Y
    Med Res Rev; 2012 Nov; 32(6):1159-96. PubMed ID: 23059763
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Network perspectives on HDM2 inhibitor chemotherapy combinations.
    Azmi AS; Beck FW; Sarkar FH; Mohammad RM
    Curr Pharm Des; 2011; 17(6):640-52. PubMed ID: 21391913
    [TBL] [Abstract][Full Text] [Related]  

  • 15. MDM2 and MDM4: p53 regulators as targets in anticancer therapy.
    Toledo F; Wahl GM
    Int J Biochem Cell Biol; 2007; 39(7-8):1476-82. PubMed ID: 17499002
    [TBL] [Abstract][Full Text] [Related]  

  • 16. [Role of p53 in leukemia].
    Kojima K
    Rinsho Ketsueki; 2014 Oct; 55(10):1724-30. PubMed ID: 25297733
    [No Abstract]   [Full Text] [Related]  

  • 17. Small-molecule MDM2 antagonists reveal aberrant p53 signaling in cancer: implications for therapy.
    Tovar C; Rosinski J; Filipovic Z; Higgins B; Kolinsky K; Hilton H; Zhao X; Vu BT; Qing W; Packman K; Myklebost O; Heimbrook DC; Vassilev LT
    Proc Natl Acad Sci U S A; 2006 Feb; 103(6):1888-93. PubMed ID: 16443686
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Pharmacological reactivation of p53 as a strategy to treat cancer.
    Zawacka-Pankau J; Selivanova G
    J Intern Med; 2015 Feb; 277(2):248-259. PubMed ID: 25495071
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Recent advances in validating MDM2 as a cancer target.
    Rayburn ER; Ezell SJ; Zhang R
    Anticancer Agents Med Chem; 2009 Oct; 9(8):882-903. PubMed ID: 19538162
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The regulation of MDM2 by multisite phosphorylation--opportunities for molecular-based intervention to target tumours?
    Meek DW; Hupp TR
    Semin Cancer Biol; 2010 Feb; 20(1):19-28. PubMed ID: 19897041
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.