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3. Shikonin exerts anti-inflammatory effects in a murine model of lipopolysaccharide-induced acute lung injury by inhibiting the nuclear factor-kappaB signaling pathway. Liang D; Sun Y; Shen Y; Li F; Song X; Zhou E; Zhao F; Liu Z; Fu Y; Guo M; Zhang N; Yang Z; Cao Y Int Immunopharmacol; 2013 Aug; 16(4):475-80. PubMed ID: 23651796 [TBL] [Abstract][Full Text] [Related]
4. Shikonin exerts antitumor activity via proteasome inhibition and cell death induction in vitro and in vivo. Yang H; Zhou P; Huang H; Chen D; Ma N; Cui QC; Shen S; Dong W; Zhang X; Lian W; Wang X; Dou QP; Liu J Int J Cancer; 2009 May; 124(10):2450-9. PubMed ID: 19165859 [TBL] [Abstract][Full Text] [Related]
5. Shikonin reduces oedema induced by phorbol ester by interfering with IkappaBalpha degradation thus inhibiting translocation of NF-kappaB to the nucleus. Andújar I; Recio MC; Bacelli T; Giner RM; Ríos JL Br J Pharmacol; 2010 May; 160(2):376-88. PubMed ID: 20423347 [TBL] [Abstract][Full Text] [Related]
6. Shikonin derivatives inhibited LPS-induced NOS in RAW 264.7 cells via downregulation of MAPK/NF-kappaB signaling. Cheng YW; Chang CY; Lin KL; Hu CM; Lin CH; Kang JJ J Ethnopharmacol; 2008 Nov; 120(2):264-71. PubMed ID: 18835347 [TBL] [Abstract][Full Text] [Related]
7. [Antitumor effect research progress of shikonin and its derivatives]. Zhu MY; Wang RB; Zhou W; Li SS Yao Xue Xue Bao; 2012 May; 47(5):588-93. PubMed ID: 22812000 [TBL] [Abstract][Full Text] [Related]
8. Shikonins, phytocompounds from Lithospermum erythrorhizon, inhibit the transcriptional activation of human tumor necrosis factor alpha promoter in vivo. Staniforth V; Wang SY; Shyur LF; Yang NS J Biol Chem; 2004 Feb; 279(7):5877-85. PubMed ID: 14645256 [TBL] [Abstract][Full Text] [Related]
9. Shikonin Promotes Skin Cell Proliferation and Inhibits Nuclear Factor-κB Translocation via Proteasome Inhibition In Vitro. Yan Y; Furumura M; Gouya T; Iwanaga A; Teye K; Numata S; Karashima T; Li XG; Hashimoto T Chin Med J (Engl); 2015 Aug; 128(16):2228-33. PubMed ID: 26265618 [TBL] [Abstract][Full Text] [Related]
10. Shikonin inhibits TNF-α production through suppressing PKC-NF-κB-dependent decrease of IL-10 in rheumatoid arthritis-like cell model. Sun WX; Liu Y; Zhou W; Li HW; Yang J; Chen ZB J Nat Med; 2017 Apr; 71(2):349-356. PubMed ID: 27943122 [TBL] [Abstract][Full Text] [Related]
11. Isobutyrylshikonin inhibits lipopolysaccharide-induced nitric oxide and prostaglandin E2 production in BV2 microglial cells by suppressing the PI3K/Akt-mediated nuclear transcription factor-κB pathway. Jayasooriya RG; Lee KT; Kang CH; Dilshara MG; Lee HJ; Choi YH; Choi IW; Kim GY Nutr Res; 2014 Dec; 34(12):1111-9. PubMed ID: 25454762 [TBL] [Abstract][Full Text] [Related]
12. [Effect of shikonin, a phytocompound from Lithospermum erythrorhizon, on rat vascular smooth muscle cells proliferation and apoptosis in vitro]. Zhang ZQ; Cao XC; Zhang L; Zhu WL Zhonghua Yi Xue Za Zhi; 2005 Jun; 85(21):1484-8. PubMed ID: 16061028 [TBL] [Abstract][Full Text] [Related]
13. Shikonin alleviates allergic airway remodeling by inhibiting the ERK-NF-κB signaling pathway. Wang TY; Zhou QL; Li M; Shang YX Int Immunopharmacol; 2017 Jul; 48():169-179. PubMed ID: 28521243 [TBL] [Abstract][Full Text] [Related]
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15. Shikonin blocks human lung adenocarcinoma cell migration and invasion in the inflammatory microenvironment via the IL‑6/STAT3 signaling pathway. Pan T; Zhang F; Li F; Gao X; Li Z; Li X; Ren X Oncol Rep; 2020 Sep; 44(3):1049-1063. PubMed ID: 32705271 [TBL] [Abstract][Full Text] [Related]
16. Shikonin attenuates lipopolysaccharide-induced acute lung injury in mice. Bai GZ; Yu HT; Ni YF; Li XF; Zhang ZP; Su K; Lei J; Liu BY; Ke CK; Zhong DX; Wang YJ; Zhao JB J Surg Res; 2013 Jun; 182(2):303-11. PubMed ID: 23158409 [TBL] [Abstract][Full Text] [Related]
17. Shikonin upregulates the expression of drug-metabolizing enzymes and drug transporters in primary rat hepatocytes. Huang CS; Chen HW; Lin TY; Lin AH; Lii CK J Ethnopharmacol; 2018 Apr; 216():18-25. PubMed ID: 29414119 [TBL] [Abstract][Full Text] [Related]
18. Shikonin, a constituent of Lithospermum erythrorhizon exhibits anti-allergic effects by suppressing orphan nuclear receptor Nr4a family gene expression as a new prototype of calcineurin inhibitors in mast cells. Wang X; Hayashi S; Umezaki M; Yamamoto T; Kageyama-Yahara N; Kondo T; Kadowaki M Chem Biol Interact; 2014 Dec; 224():117-27. PubMed ID: 25451590 [TBL] [Abstract][Full Text] [Related]
19. Donepezil, an acetylcholinesterase inhibitor, attenuates LPS-induced inflammatory response in murine macrophage cell line RAW 264.7 through inhibition of nuclear factor kappa B translocation. Arikawa M; Kakinuma Y; Noguchi T; Todaka H; Sato T Eur J Pharmacol; 2016 Oct; 789():17-26. PubMed ID: 27373848 [TBL] [Abstract][Full Text] [Related]
20. Shikonin exerts anti-inflammatory effects in LPS-induced mastitis by inhibiting NF-κB signaling pathway. Yang C; Liu P; Wang S; Zhao G; Zhang T; Guo S; Jiang K; Wu H; Deng G Biochem Biophys Res Commun; 2018 Oct; 505(1):1-6. PubMed ID: 30224056 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]