224 related articles for article (PubMed ID: 21393858)
1. SHP-2/PTPN11 mediates gliomagenesis driven by PDGFRA and INK4A/ARF aberrations in mice and humans.
Liu KW; Feng H; Bachoo R; Kazlauskas A; Smith EM; Symes K; Hamilton RL; Nagane M; Nishikawa R; Hu B; Cheng SY
J Clin Invest; 2011 Mar; 121(3):905-17. PubMed ID: 21393858
[TBL] [Abstract][Full Text] [Related]
2. Dynamin 2 mediates PDGFRα-SHP-2-promoted glioblastoma growth and invasion.
Feng H; Liu KW; Guo P; Zhang P; Cheng T; McNiven MA; Johnson GR; Hu B; Cheng SY
Oncogene; 2012 May; 31(21):2691-702. PubMed ID: 21996738
[TBL] [Abstract][Full Text] [Related]
3. SHP-2-upregulated ZEB1 is important for PDGFRα-driven glioma epithelial-mesenchymal transition and invasion in mice and humans.
Zhang L; Zhang W; Li Y; Alvarez A; Li Z; Wang Y; Song L; Lv D; Nakano I; Hu B; Cheng SY; Feng H
Oncogene; 2016 Oct; 35(43):5641-5652. PubMed ID: 27041571
[TBL] [Abstract][Full Text] [Related]
4. Targeting PDGFRα-activated glioblastoma through specific inhibition of SHP-2-mediated signaling.
Sang Y; Hou Y; Cheng R; Zheng L; Alvarez AA; Hu B; Cheng SY; Zhang W; Li Y; Feng H
Neuro Oncol; 2019 Nov; 21(11):1423-1435. PubMed ID: 31232447
[TBL] [Abstract][Full Text] [Related]
5. Ink4a-Arf loss cooperates with KRas activation in astrocytes and neural progenitors to generate glioblastomas of various morphologies depending on activated Akt.
Uhrbom L; Dai C; Celestino JC; Rosenblum MK; Fuller GN; Holland EC
Cancer Res; 2002 Oct; 62(19):5551-8. PubMed ID: 12359767
[TBL] [Abstract][Full Text] [Related]
6. ROS fusion tyrosine kinase activates a SH2 domain-containing phosphatase-2/phosphatidylinositol 3-kinase/mammalian target of rapamycin signaling axis to form glioblastoma in mice.
Charest A; Wilker EW; McLaughlin ME; Lane K; Gowda R; Coven S; McMahon K; Kovach S; Feng Y; Yaffe MB; Jacks T; Housman D
Cancer Res; 2006 Aug; 66(15):7473-81. PubMed ID: 16885344
[TBL] [Abstract][Full Text] [Related]
7. Protein kinase A-dependent phosphorylation of Dock180 at serine residue 1250 is important for glioma growth and invasion stimulated by platelet derived-growth factor receptor α.
Feng H; Li Y; Yin Y; Zhang W; Hou Y; Zhang L; Li Z; Xie B; Gao WQ; Sarkaria JN; Raizer JJ; James CD; Parsa AT; Hu B; Cheng SY
Neuro Oncol; 2015 Jun; 17(6):832-42. PubMed ID: 25468898
[TBL] [Abstract][Full Text] [Related]
8. Activation of Rac1 by Src-dependent phosphorylation of Dock180(Y1811) mediates PDGFRα-stimulated glioma tumorigenesis in mice and humans.
Feng H; Hu B; Liu KW; Li Y; Lu X; Cheng T; Yiin JJ; Lu S; Keezer S; Fenton T; Furnari FB; Hamilton RL; Vuori K; Sarkaria JN; Nagane M; Nishikawa R; Cavenee WK; Cheng SY
J Clin Invest; 2011 Dec; 121(12):4670-84. PubMed ID: 22080864
[TBL] [Abstract][Full Text] [Related]
9. Double minute amplification of mutant PDGF receptor α in a mouse glioma model.
Zou H; Feng R; Huang Y; Tripodi J; Najfeld V; Tsankova NM; Jahanshahi M; Olson LE; Soriano P; Friedel RH
Sci Rep; 2015 Feb; 5():8468. PubMed ID: 25683249
[TBL] [Abstract][Full Text] [Related]
10. Platelet-derived growth factor receptor alpha in glioma: a bad seed.
Liu KW; Hu B; Cheng SY
Chin J Cancer; 2011 Sep; 30(9):590-602. PubMed ID: 21880180
[TBL] [Abstract][Full Text] [Related]
11. PI3K-mediated PDGFRα signaling regulates survival and proliferation in skeletal development through p53-dependent intracellular pathways.
Fantauzzo KA; Soriano P
Genes Dev; 2014 May; 28(9):1005-17. PubMed ID: 24788519
[TBL] [Abstract][Full Text] [Related]
12. Activated BRAF induces gliomas in mice when combined with Ink4a/Arf loss or Akt activation.
Robinson JP; VanBrocklin MW; Guilbeault AR; Signorelli DL; Brandner S; Holmen SL
Oncogene; 2010 Jan; 29(3):335-44. PubMed ID: 19855433
[TBL] [Abstract][Full Text] [Related]
13. The tyrosine phosphatase SHP-2 is required for mediating phosphatidylinositol 3-kinase/Akt activation by growth factors.
Wu CJ; O'Rourke DM; Feng GS; Johnson GR; Wang Q; Greene MI
Oncogene; 2001 Sep; 20(42):6018-25. PubMed ID: 11593409
[TBL] [Abstract][Full Text] [Related]
14. Cell type-specific tumor suppression by Ink4a and Arf in Kras-induced mouse gliomagenesis.
Uhrbom L; Kastemar M; Johansson FK; Westermark B; Holland EC
Cancer Res; 2005 Mar; 65(6):2065-9. PubMed ID: 15781613
[TBL] [Abstract][Full Text] [Related]
15. Ink4a/Arf loss promotes tumor recurrence following Ras inhibition.
Vanbrocklin MW; Robinson JP; Lastwika KJ; McKinney AJ; Gach HM; Holmen SL
Neuro Oncol; 2012 Jan; 14(1):34-42. PubMed ID: 22015595
[TBL] [Abstract][Full Text] [Related]
16. IGFBP2 is a candidate biomarker for Ink4a-Arf status and a therapeutic target for high-grade gliomas.
Moore LM; Holmes KM; Smith SM; Wu Y; Tchougounova E; Uhrbom L; Sawaya R; Bruner JM; Fuller GN; Zhang W
Proc Natl Acad Sci U S A; 2009 Sep; 106(39):16675-9. PubMed ID: 19805356
[TBL] [Abstract][Full Text] [Related]
17. Bmi1 controls tumor development in an Ink4a/Arf-independent manner in a mouse model for glioma.
Bruggeman SW; Hulsman D; Tanger E; Buckle T; Blom M; Zevenhoven J; van Tellingen O; van Lohuizen M
Cancer Cell; 2007 Oct; 12(4):328-41. PubMed ID: 17936558
[TBL] [Abstract][Full Text] [Related]
18. Gliomagenesis arising from Pten- and Ink4a/Arf-deficient neural progenitor cells is mediated by the p53-Fbxw7/Cdc4 pathway, which controls c-Myc.
Kim HS; Woolard K; Lai C; Bauer PO; Maric D; Song H; Li A; Kotliarova S; Zhang W; Fine HA
Cancer Res; 2012 Nov; 72(22):6065-75. PubMed ID: 22986743
[TBL] [Abstract][Full Text] [Related]
19. The inhibitor of cyclin-dependent kinase 4a/alternative reading frame (INK4a/ARF) locus encoded proteins p16INK4a and p19ARF repress cyclin D1 transcription through distinct cis elements.
D'Amico M; Wu K; Fu M; Rao M; Albanese C; Russell RG; Lian H; Bregman D; White MA; Pestell RG
Cancer Res; 2004 Jun; 64(12):4122-30. PubMed ID: 15205322
[TBL] [Abstract][Full Text] [Related]
20. Transactivation of platelet-derived growth factor receptor alpha by the GTPase-deficient activated mutant of Galpha12.
Kumar RN; Ha JH; Radhakrishnan R; Dhanasekaran DN
Mol Cell Biol; 2006 Jan; 26(1):50-62. PubMed ID: 16354679
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
