BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

256 related articles for article (PubMed ID: 21396941)

  • 1. Crystal structure of human enterovirus 71 3C protease.
    Cui S; Wang J; Fan T; Qin B; Guo L; Lei X; Wang J; Wang M; Jin Q
    J Mol Biol; 2011 May; 408(3):449-61. PubMed ID: 21396941
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Crystal structures of enterovirus 71 3C protease complexed with rupintrivir reveal the roles of catalytically important residues.
    Wang J; Fan T; Yao X; Wu Z; Guo L; Lei X; Wang J; Wang M; Jin Q; Cui S
    J Virol; 2011 Oct; 85(19):10021-30. PubMed ID: 21813612
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A Novel Enterovirus 71 (EV71) Virulence Determinant: The 69th Residue of 3C Protease Modulates Pathogenicity.
    Li B; Yue Y; Zhang Y; Yuan Z; Li P; Song N; Lin W; Liu Y; Gu L; Meng H
    Front Cell Infect Microbiol; 2017; 7():26. PubMed ID: 28217559
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structures of Enterovirus 71 3C proteinase (strain E2004104-TW-CDC) and its complex with rupintrivir.
    Wu C; Cai Q; Chen C; Li N; Peng X; Cai Y; Yin K; Chen X; Wang X; Zhang R; Liu L; Chen S; Li J; Lin T
    Acta Crystallogr D Biol Crystallogr; 2013 May; 69(Pt 5):866-71. PubMed ID: 23633597
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification and biochemical characterization of DC07090 as a novel potent small molecule inhibitor against human enterovirus 71 3C protease by structure-based virtual screening.
    Ma GH; Ye Y; Zhang D; Xu X; Si P; Peng JL; Xiao YL; Cao RY; Yin YL; Chen J; Zhao LX; Zhou Y; Zhong W; Liu H; Luo XM; Chen LL; Shen X
    Eur J Med Chem; 2016 Nov; 124():981-991. PubMed ID: 27776325
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Crystal structure of 2A proteinase from hand, foot and mouth disease virus.
    Mu Z; Wang B; Zhang X; Gao X; Qin B; Zhao Z; Cui S
    J Mol Biol; 2013 Nov; 425(22):4530-43. PubMed ID: 23973886
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural and mutagenic analysis of foot-and-mouth disease virus 3C protease reveals the role of the beta-ribbon in proteolysis.
    Sweeney TR; Roqué-Rosell N; Birtley JR; Leatherbarrow RJ; Curry S
    J Virol; 2007 Jan; 81(1):115-24. PubMed ID: 17065215
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structure of the Enterovirus 71 3C Protease in Complex with NK-1.8k and Indications for the Development of Antienterovirus Protease Inhibitor.
    Wang Y; Cao L; Zhai Y; Yin Z; Sun Y; Shang L
    Antimicrob Agents Chemother; 2017 Jul; 61(7):. PubMed ID: 28461310
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Peptidomimetic ethyl propenoate covalent inhibitors of the enterovirus 71 3C protease: a P2-P4 study.
    Ang MJ; Lau QY; Ng FM; Then SW; Poulsen A; Cheong YK; Ngoh ZX; Tan YW; Peng J; Keller TH; Hill J; Chu JJ; Chia CS
    J Enzyme Inhib Med Chem; 2016; 31(2):332-9. PubMed ID: 25792507
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of enterovirus 71 replication and viral 3C protease by quercetin.
    Yao C; Xi C; Hu K; Gao W; Cai X; Qin J; Lv S; Du C; Wei Y
    Virol J; 2018 Jul; 15(1):116. PubMed ID: 30064445
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural basis for antiviral inhibition of the main protease, 3C, from human enterovirus 93.
    Costenaro L; Kaczmarska Z; Arnan C; Janowski R; Coutard B; Solà M; Gorbalenya AE; Norder H; Canard B; Coll M
    J Virol; 2011 Oct; 85(20):10764-73. PubMed ID: 21835784
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Activity-Based Protein Profiling Identifies ATG4B as a Key Host Factor for Enterovirus 71 Proliferation.
    Sun Y; Zheng Q; Wang Y; Pang Z; Liu J; Yin Z; Lou Z
    J Virol; 2019 Dec; 93(24):. PubMed ID: 31554687
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Enterovirus 71 and coxsackievirus A16 3C proteases: binding to rupintrivir and their substrates and anti-hand, foot, and mouth disease virus drug design.
    Lu G; Qi J; Chen Z; Xu X; Gao F; Lin D; Qian W; Liu H; Jiang H; Yan J; Gao GF
    J Virol; 2011 Oct; 85(19):10319-31. PubMed ID: 21795339
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Insights into cleavage specificity from the crystal structure of foot-and-mouth disease virus 3C protease complexed with a peptide substrate.
    Zunszain PA; Knox SR; Sweeney TR; Yang J; Roqué-Rosell N; Belsham GJ; Leatherbarrow RJ; Curry S
    J Mol Biol; 2010 Jan; 395(2):375-89. PubMed ID: 19883658
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Optimize the interactions at S4 with efficient inhibitors targeting 3C proteinase from enterovirus 71.
    Zhang L; Huang G; Cai Q; Zhao C; Tang L; Ren H; Li P; Li N; Huang J; Chen X; Guan Y; You H; Chen S; Li J; Lin T
    J Mol Recognit; 2016 Nov; 29(11):520-527. PubMed ID: 27185390
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Enterovirus 71 3C protease cleaves a novel target CstF-64 and inhibits cellular polyadenylation.
    Weng KF; Li ML; Hung CT; Shih SR
    PLoS Pathog; 2009 Sep; 5(9):e1000593. PubMed ID: 19779565
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cleavage of the adaptor protein TRIF by enterovirus 71 3C inhibits antiviral responses mediated by Toll-like receptor 3.
    Lei X; Sun Z; Liu X; Jin Q; He B; Wang J
    J Virol; 2011 Sep; 85(17):8811-8. PubMed ID: 21697485
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Autoprocessing: an essential step for expression and purification of enterovirus 71 3C(pro) in Escherichia coli.
    Huang S; Lyu Y; Qing X; Wang W; Tang L; Cheng K; Wang W
    Biotechnol Lett; 2013 Nov; 35(11):1845-52. PubMed ID: 23881322
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Crystal structure of foot-and-mouth disease virus 3C protease. New insights into catalytic mechanism and cleavage specificity.
    Birtley JR; Knox SR; Jaulent AM; Brick P; Leatherbarrow RJ; Curry S
    J Biol Chem; 2005 Mar; 280(12):11520-7. PubMed ID: 15654079
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Development of a luciferase-based biosensor to assess enterovirus 71 3C protease activity in living cells.
    Zhang Y; Ke X; Zheng C; Liu Y; Xie L; Zheng Z; Wang H
    Sci Rep; 2017 Sep; 7(1):10385. PubMed ID: 28871120
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.