192 related articles for article (PubMed ID: 21398423)
1. Enigmol: a novel sphingolipid analogue with anticancer activity against cancer cell lines and in vivo models for intestinal and prostate cancer.
Symolon H; Bushnev A; Peng Q; Ramaraju H; Mays SG; Allegood JC; Pruett ST; Sullards MC; Dillehay DL; Liotta DC; Merrill AH
Mol Cancer Ther; 2011 Apr; 10(4):648-57. PubMed ID: 21398423
[TBL] [Abstract][Full Text] [Related]
2. Modulation of intracellular beta-catenin localization and intestinal tumorigenesis in vivo and in vitro by sphingolipids.
Schmelz EM; Roberts PC; Kustin EM; Lemonnier LA; Sullards MC; Dillehay DL; Merrill AH
Cancer Res; 2001 Sep; 61(18):6723-9. PubMed ID: 11559543
[TBL] [Abstract][Full Text] [Related]
3. Novel synthesis and biological evaluation of enigmols as therapeutic agents for treating prostate cancer.
Garnier-Amblard EC; Mays SG; Arrendale RF; Baillie MT; Bushnev AS; Culver DG; Evers TJ; Holt JJ; Howard RB; Liebeskind LS; Menaldino DS; Natchus MG; Petros JA; Ramaraju H; Reddy GP; Liotta DC
ACS Med Chem Lett; 2011 Jun; 2(6):438-43. PubMed ID: 24900327
[TBL] [Abstract][Full Text] [Related]
4. A targeted constitutive mutation in the APC tumor suppressor gene underlies mammary but not intestinal tumorigenesis.
Gaspar C; Franken P; Molenaar L; Breukel C; van der Valk M; Smits R; Fodde R
PLoS Genet; 2009 Jul; 5(7):e1000547. PubMed ID: 19578404
[TBL] [Abstract][Full Text] [Related]
5. Biodiversity of sphingoid bases ("sphingosines") and related amino alcohols.
Pruett ST; Bushnev A; Hagedorn K; Adiga M; Haynes CA; Sullards MC; Liotta DC; Merrill AH
J Lipid Res; 2008 Aug; 49(8):1621-39. PubMed ID: 18499644
[TBL] [Abstract][Full Text] [Related]
6. Discovery of a Fluorinated Enigmol Analog with Enhanced in Vivo Pharmacokinetic and Anti-Tumor Properties.
Miller EJ; Mays SG; Baillie MT; Howard RB; Culver DG; Saindane M; Pruett ST; Holt JJ; Menaldino DS; Evers TJ; Reddy GP; Arrendale RF; Natchus MG; Petros JA; Liotta DC
ACS Med Chem Lett; 2016 May; 7(5):537-42. PubMed ID: 27190606
[TBL] [Abstract][Full Text] [Related]
7. Sphingoid bases and ceramide induce apoptosis in HT-29 and HCT-116 human colon cancer cells.
Ahn EH; Schroeder JJ
Exp Biol Med (Maywood); 2002 May; 227(5):345-53. PubMed ID: 11976405
[TBL] [Abstract][Full Text] [Related]
8. The threshold level of adenomatous polyposis coli protein for mouse intestinal tumorigenesis.
Li Q; Ishikawa TO; Oshima M; Taketo MM
Cancer Res; 2005 Oct; 65(19):8622-7. PubMed ID: 16204028
[TBL] [Abstract][Full Text] [Related]
9. Sphingoid bases and de novo ceramide synthesis: enzymes involved, pharmacology and mechanisms of action.
Menaldino DS; Bushnev A; Sun A; Liotta DC; Symolon H; Desai K; Dillehay DL; Peng Q; Wang E; Allegood J; Trotman-Pruett S; Sullards MC; Merrill AH
Pharmacol Res; 2003 May; 47(5):373-81. PubMed ID: 12676511
[TBL] [Abstract][Full Text] [Related]
10. Scutellaria barbata D. Don inhibits colorectal cancer growth via suppression of Wnt/β-catenin signaling pathway.
Wei LH; Lin JM; Chu JF; Chen HW; Li QY; Peng J
Chin J Integr Med; 2017 Nov; 23(11):858-863. PubMed ID: 29080197
[TBL] [Abstract][Full Text] [Related]
11. Adenomatous polyposis coli genotype-dependent toll-like receptor 4 activity in colon cancer.
Wen F; Liu Y; Wang W; Li M; Guo F; Sang Y; Qin Q; Wang Y; Li Q
Oncotarget; 2016 Feb; 7(7):7761-72. PubMed ID: 26760960
[TBL] [Abstract][Full Text] [Related]
12. Response of Apc(min) and A33 (delta N beta-cat) mutant mice to treatment with tea, sulindac, and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).
Orner GA; Dashwood WM; Blum CA; Díaz GD; Li Q; Al-Fageeh M; Tebbutt N; Heath JK; Ernst M; Dashwood RH
Mutat Res; 2002 Sep; 506-507():121-7. PubMed ID: 12351151
[TBL] [Abstract][Full Text] [Related]
13. E7386, a Selective Inhibitor of the Interaction between β-Catenin and CBP, Exerts Antitumor Activity in Tumor Models with Activated Canonical Wnt Signaling.
Yamada K; Hori Y; Inoue S; Yamamoto Y; Iso K; Kamiyama H; Yamaguchi A; Kimura T; Uesugi M; Ito J; Matsuki M; Nakamoto K; Harada H; Yoneda N; Takemura A; Kushida I; Wakayama N; Kubara K; Kato Y; Semba T; Yokoi A; Matsukura M; Odagami T; Iwata M; Tsuruoka A; Uenaka T; Matsui J; Matsushima T; Nomoto K; Kouji H; Owa T; Funahashi Y; Ozawa Y
Cancer Res; 2021 Feb; 81(4):1052-1062. PubMed ID: 33408116
[TBL] [Abstract][Full Text] [Related]
14. RUNX3 attenuates beta-catenin/T cell factors in intestinal tumorigenesis.
Ito K; Lim AC; Salto-Tellez M; Motoda L; Osato M; Chuang LS; Lee CW; Voon DC; Koo JK; Wang H; Fukamachi H; Ito Y
Cancer Cell; 2008 Sep; 14(3):226-37. PubMed ID: 18772112
[TBL] [Abstract][Full Text] [Related]
15. TRIB3 Interacts With β-Catenin and TCF4 to Increase Stem Cell Features of Colorectal Cancer Stem Cells and Tumorigenesis.
Hua F; Shang S; Yang YW; Zhang HZ; Xu TL; Yu JJ; Zhou DD; Cui B; Li K; Lv XX; Zhang XW; Liu SS; Yu JM; Wang F; Zhang C; Huang B; Hu ZW
Gastroenterology; 2019 Feb; 156(3):708-721.e15. PubMed ID: 30365932
[TBL] [Abstract][Full Text] [Related]
16. SGK1-dependent intestinal tumor growth in APC-deficient mice.
Wang K; Gu S; Nasir O; Föller M; Ackermann TF; Klingel K; Kandolf R; Kuhl D; Stournaras C; Lang F
Cell Physiol Biochem; 2010; 25(2-3):271-8. PubMed ID: 20110688
[TBL] [Abstract][Full Text] [Related]
17. RK-287107, a potent and specific tankyrase inhibitor, blocks colorectal cancer cell growth in a preclinical model.
Mizutani A; Yashiroda Y; Muramatsu Y; Yoshida H; Chikada T; Tsumura T; Okue M; Shirai F; Fukami T; Yoshida M; Seimiya H
Cancer Sci; 2018 Dec; 109(12):4003-4014. PubMed ID: 30238564
[TBL] [Abstract][Full Text] [Related]
18. Safingol toxicology after oral administration to TRAMP mice: demonstration of safingol uptake and metabolism by N-acylation and N-methylation.
Morales PR; Dillehay DL; Moody SJ; Pallas DC; Pruett S; Allgood JC; Symolon H; Merrill AH
Drug Chem Toxicol; 2007; 30(3):197-216. PubMed ID: 17613006
[TBL] [Abstract][Full Text] [Related]
19. Phytoceramide and sphingoid bases derived from brewer's yeast Saccharomyces pastorianus activate peroxisome proliferator-activated receptors.
Murakami I; Wakasa Y; Yamashita S; Kurihara T; Zama K; Kobayashi N; Mizutani Y; Mitsutake S; Shigyo T; Igarashi Y
Lipids Health Dis; 2011 Aug; 10():150. PubMed ID: 21861924
[TBL] [Abstract][Full Text] [Related]
20. Disruption of sphingolipid metabolism and stimulation of DNA synthesis by fumonisin B1. A molecular mechanism for carcinogenesis associated with Fusarium moniliforme.
Schroeder JJ; Crane HM; Xia J; Liotta DC; Merrill AH
J Biol Chem; 1994 Feb; 269(5):3475-81. PubMed ID: 8106389
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
