191 related articles for article (PubMed ID: 2140289)
1. Relationship between dose rate of [6RS]Leucovorin administration, plasma concentrations of reduced folates, and pools of 5,10-methylenetetrahydrofolates and tetrahydrofolates in human colon adenocarcinoma xenografts.
Houghton JA; Williams LG; de Graaf SS; Cheshire PJ; Rodman JH; Maneval DC; Wainer IW; Jadaud P; Houghton PJ
Cancer Res; 1990 Jun; 50(12):3493-502. PubMed ID: 2140289
[TBL] [Abstract][Full Text] [Related]
2. Influence of dose of [6RS]leucovorin on reduced folate pools and 5-fluorouracil-mediated thymidylate synthase inhibition in human colon adenocarcinoma xenografts.
Houghton JA; Williams LG; Cheshire PJ; Wainer IW; Jadaud P; Houghton PJ
Cancer Res; 1990 Jul; 50(13):3940-6. PubMed ID: 2354443
[TBL] [Abstract][Full Text] [Related]
3. Factors that influence the therapeutic activity of 5-fluorouracil [6RS]leucovorin combinations in colon adenocarcinoma xenografts.
Houghton JA; Williams LG; Loftin SK; Cheshire PJ; Morton CL; Houghton PJ; Dayan A; Jolivet J
Cancer Chemother Pharmacol; 1992; 30(6):423-32. PubMed ID: 1394798
[TBL] [Abstract][Full Text] [Related]
4. Comparison of the conversion of 5-formyltetrahydrofolate and 5-methyltetrahydrofolate to 5,10-methylenetetrahydrofolates and tetrahydrofolates in human colon tumors.
Houghton JA; Williams LG; de Graaf SS; Cheshire PJ; Wainer IW; Jadaud P; Houghton PJ
Cancer Commun; 1989; 1(3):167-74. PubMed ID: 2639728
[TBL] [Abstract][Full Text] [Related]
5. Mutation(s) of the thymidylate synthase gene of human adenocarcinoma cells causes a thymidylate synthase-negative phenotype that can be attenuated by exogenous folates.
Houghton PJ; Rahman A; Will CL; Dolnick BJ; Houghton JA
Cancer Res; 1992 Feb; 52(3):558-65. PubMed ID: 1732043
[TBL] [Abstract][Full Text] [Related]
6. Characterization of the pools of 5,10-methylenetetrahydrofolates and tetrahydrofolates in xenografts of human colon adenocarcinoma.
Houghton JA; Williams LG; Radparvar S; Houghton PJ
Cancer Res; 1988 Jun; 48(11):3062-9. PubMed ID: 3365696
[TBL] [Abstract][Full Text] [Related]
7. Effect of polyglutamylation of 5,10-methylenetetrahydrofolate on the binding of 5-fluoro-2'-deoxyuridylate to thymidylate synthase purified from a human colon adenocarcinoma xenograft.
Radparvar S; Houghton PJ; Houghton JA
Biochem Pharmacol; 1989 Jan; 38(2):335-42. PubMed ID: 2914018
[TBL] [Abstract][Full Text] [Related]
8. Binding of 5-fluorodeoxyuridylate to thymidylate synthase in human colon adenocarcinoma xenografts.
Houghton JA; Torrance PM; Radparvar S; Williams LG; Houghton PJ
Eur J Cancer Clin Oncol; 1986 Apr; 22(4):505-10. PubMed ID: 3732354
[TBL] [Abstract][Full Text] [Related]
9. Role for cytosolic folate-binding proteins in the compartmentation of endogenous tetrahydrofolates and the 5-formyl tetrahydrofolate-mediated enhancement of 5-fluoro-2'-deoxyuridine antitumor activity in vitro.
Matherly LH; Czajkowski CA; Muench SP; Psiakis JT
Cancer Res; 1990 Jun; 50(11):3262-9. PubMed ID: 2139802
[TBL] [Abstract][Full Text] [Related]
10. Relationship between 5-fluoro-2'-deoxyuridylate, 2'-deoxyuridylate, and thymidylate synthase activity subsequent to 5-fluorouracil administration, in xenografts of human colon adenocarcinomas.
Houghton JA; Weiss KD; Williams LG; Torrance PM; Houghton PJ
Biochem Pharmacol; 1986 Apr; 35(8):1351-8. PubMed ID: 3008760
[TBL] [Abstract][Full Text] [Related]
11. Plasma and tumor tissue pharmacology of high-dose intravenous leucovorin calcium in combination with fluorouracil in patients with advanced colorectal carcinoma.
Trave F; Rustum YM; Petrelli NJ; Herrera L; Mittelman A; Frank C; Creaven PJ
J Clin Oncol; 1988 Jul; 6(7):1184-91. PubMed ID: 3260621
[TBL] [Abstract][Full Text] [Related]
12. Accumulation of tetrahydrofolates in human plasma after leucovorin administration.
Bunni MA; Rembiesa BM; Priest DG; Sahovic E; Stuart R
Cancer Chemother Pharmacol; 1989; 23(6):353-7. PubMed ID: 2785439
[TBL] [Abstract][Full Text] [Related]
13. Potentiation of 5-fluorouracil-leucovorin activity by alpha2a-interferon in colon adenocarcinoma xenografts.
Houghton JA; Cheshire PJ; Morton CL; Stewart CF
Clin Cancer Res; 1995 Jan; 1(1):33-40. PubMed ID: 9815884
[TBL] [Abstract][Full Text] [Related]
14. Pharmacologic rationale for fluoropyrimidine-leucovorin combination: biochemical mechanisms.
Zhang ZG; Rustum YM
Semin Oncol; 1992 Apr; 19(2 Suppl 4):46-50. PubMed ID: 1532459
[TBL] [Abstract][Full Text] [Related]
15. Effect of folinic acid on fluorouracil activity and expression of thymidylate synthase.
van der Wilt CL; Pinedo HM; Smid K; Cloos J; Noordhuis P; Peters GJ
Semin Oncol; 1992 Apr; 19(2 Suppl 3):16-25. PubMed ID: 1532671
[TBL] [Abstract][Full Text] [Related]
16. Effects of diastereoisomers of 5-formyltetrahydrofolate on cellular growth, sensitivity to 5-fluoro-2'-deoxyuridine, and methylenetetrahydrofolate polyglutamate levels in HCT-8 cells.
Zhang ZG; Rustum YM
Cancer Res; 1991 Jul; 51(13):3476-81. PubMed ID: 2054787
[TBL] [Abstract][Full Text] [Related]
17. Mechanism of the cytotoxic synergism of fluoropyrimidines and folinic acid in mouse leukemic cells.
Keyomarsi K; Moran RG
J Biol Chem; 1988 Oct; 263(28):14402-9. PubMed ID: 2971656
[TBL] [Abstract][Full Text] [Related]
18. Pharmacokinetics of leucovorin (D,L-5-formyltetrahydrofolate) after intravenous injection and constant intravenous infusion.
Straw JA; Newman EM; Doroshow JH
NCI Monogr; 1987; (5):41-5. PubMed ID: 3501545
[TBL] [Abstract][Full Text] [Related]
19. Characteristics of thymidylate synthase purified from a human colon adenocarcinoma.
Radparvar S; Houghton PJ; Houghton JA
Arch Biochem Biophys; 1988 Jan; 260(1):342-50. PubMed ID: 3341747
[TBL] [Abstract][Full Text] [Related]
20. Biochemical modulation of fluorouracil with leucovorin and interferon: preclinical and clinical investigations.
Grem JL; Chu E; Boarman D; Balis FM; Murphy RF; McAtee N; Allegra CJ
Semin Oncol; 1992 Apr; 19(2 Suppl 3):36-44. PubMed ID: 1557656
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
