152 related articles for article (PubMed ID: 21403643)
1. Tenofovir renal proximal tubular toxicity is regulated by OAT1 and MRP4 transporters.
Kohler JJ; Hosseini SH; Green E; Abuin A; Ludaway T; Russ R; Santoianni R; Lewis W
Lab Invest; 2011 Jun; 91(6):852-8. PubMed ID: 21403643
[TBL] [Abstract][Full Text] [Related]
2. Depletion of the cellular antioxidant system contributes to tenofovir disoproxil fumarate - induced mitochondrial damage and increased oxido-nitrosative stress in the kidney.
Abraham P; Ramamoorthy H; Isaac B
J Biomed Sci; 2013 Aug; 20(1):61. PubMed ID: 23957306
[TBL] [Abstract][Full Text] [Related]
3. In vitro cytotoxicity and mitochondrial toxicity of tenofovir alone and in combination with other antiretrovirals in human renal proximal tubule cells.
Vidal F; Domingo JC; Guallar J; Saumoy M; Cordobilla B; Sánchez de la Rosa R; Giralt M; Alvarez ML; López-Dupla M; Torres F; Villarroya F; Cihlar T; Domingo P
Antimicrob Agents Chemother; 2006 Nov; 50(11):3824-32. PubMed ID: 16940060
[TBL] [Abstract][Full Text] [Related]
4. Tenofovir disoproxil fumarate: toxicity, toxicokinetics, and toxicogenomics analysis after 13 weeks of oral administration in mice.
Ng HH; Stock H; Rausch L; Bunin D; Wang A; Brill S; Gow J; Mirsalis JC
Int J Toxicol; 2015; 34(1):4-10. PubMed ID: 25568137
[TBL] [Abstract][Full Text] [Related]
5. Improvement of Protein Expression Profile in Three-Dimensional Renal Proximal Tubular Epithelial Cell Spheroids Selected Based on OAT1 Gene Expression: A Potential In Vitro Tool for Evaluating Human Renal Proximal Tubular Toxicity and Drug Disposition.
Ishiguro N; Takahashi E; Arakawa H; Saito A; Kitagawa F; Kondo M; Morinaga G; Takatani M; Takahashi R; Kudo T; Mae SI; Kadoguchi M; Higuchi D; Nakazono Y; Tamai I; Osafune K; Jimbo Y
Drug Metab Dispos; 2023 Sep; 51(9):1177-1187. PubMed ID: 37385755
[TBL] [Abstract][Full Text] [Related]
6. Albumin-bound kynurenic acid is an appropriate endogenous biomarker for assessment of the renal tubular OATs-MRP4 channel.
Ma Y; Ran F; Xin M; Gou X; Wang X; Wu X
J Pharm Anal; 2023 Oct; 13(10):1205-1220. PubMed ID: 38024860
[TBL] [Abstract][Full Text] [Related]
7. Brincidofovir Is Not a Substrate for the Human Organic Anion Transporter 1: A Mechanistic Explanation for the Lack of Nephrotoxicity Observed in Clinical Studies.
Tippin TK; Morrison ME; Brundage TM; Momméja-Marin H
Ther Drug Monit; 2016 Dec; 38(6):777-786. PubMed ID: 27851688
[TBL] [Abstract][Full Text] [Related]
8. Preclinical efficacy of melatonin in the amelioration of tenofovir nephrotoxicity by the attenuation of oxidative stress, nitrosative stress, and inflammation in rats.
Ramamoorthy H; Abraham P; Isaac B
J Basic Clin Physiol Pharmacol; 2014 Jan; ():1-13. PubMed ID: 24468618
[TBL] [Abstract][Full Text] [Related]
9. MDR1 transporter protects against paraquat-induced toxicity in human and mouse proximal tubule cells.
Wen X; Gibson CJ; Yang I; Buckley B; Goedken MJ; Richardson JR; Aleksunes LM
Toxicol Sci; 2014 Oct; 141(2):475-83. PubMed ID: 25015657
[TBL] [Abstract][Full Text] [Related]
10. Uraemic toxins induce proximal tubular injury via organic anion transporter 1-mediated uptake.
Motojima M; Hosokawa A; Yamato H; Muraki T; Yoshioka T
Br J Pharmacol; 2002 Jan; 135(2):555-63. PubMed ID: 11815391
[TBL] [Abstract][Full Text] [Related]
11. Raltegravir is a substrate for SLC22A6: a putative mechanism for the interaction between raltegravir and tenofovir.
Moss DM; Kwan WS; Liptrott NJ; Smith DL; Siccardi M; Khoo SH; Back DJ; Owen A
Antimicrob Agents Chemother; 2011 Feb; 55(2):879-87. PubMed ID: 21078936
[TBL] [Abstract][Full Text] [Related]
12. Tenofovir disoproxil fumarate induces peripheral neuropathy and alters inflammation and mitochondrial biogenesis in the brains of mice.
Fields JA; Swinton MK; Carson A; Soontornniyomkij B; Lindsay C; Han MM; Frizzi K; Sambhwani S; Murphy A; Achim CL; Ellis RJ; Calcutt NA
Sci Rep; 2019 Nov; 9(1):17158. PubMed ID: 31748578
[TBL] [Abstract][Full Text] [Related]
13. Understanding adefovir pharmacokinetics as a component of a transporter phenotyping cocktail.
Dong Q; Chen C; Taubert M; Bilal M; Kinzig M; Sörgel F; Scherf-Clavel O; Fuhr U; Dokos C
Eur J Clin Pharmacol; 2024 Jul; 80(7):1069-1078. PubMed ID: 38546841
[TBL] [Abstract][Full Text] [Related]
14. Molecular basis for selective uptake and elimination of organic anions in the kidney by OAT1.
Parker JL; Kato T; Kuteyi G; Sitsel O; Newstead S
Nat Struct Mol Biol; 2023 Nov; 30(11):1786-1793. PubMed ID: 37482561
[TBL] [Abstract][Full Text] [Related]
15. Mitotherapy inhibits against tenofovir induced nephrotoxicity on rat renal proximal tubular cells.
Hosseini MJ; Hassanbeigloo A; Abbasi H; Arjmand A; Sherkat F; Pourahmad J
Biochem Biophys Rep; 2024 Jul; 38():101669. PubMed ID: 38434141
[TBL] [Abstract][Full Text] [Related]
16. Remote effects of kidney drug transporter OAT1 on gut microbiome composition and urate homeostasis.
Ermakov VS; Granados JC; Nigam SK
JCI Insight; 2023 Nov; 8(21):. PubMed ID: 37937647
[TBL] [Abstract][Full Text] [Related]
17. Transport activity regulates mitochondrial bioenergetics and biogenesis in renal tubules.
Cheng CJ; Nizar JM; Dai DF; Huang CL
FASEB J; 2024 May; 38(10):e23703. PubMed ID: 38805156
[TBL] [Abstract][Full Text] [Related]
18. Investigating Organ Toxicity Profile of Tenofovir and Tenofovir Nanoparticle on the Liver and Kidney: Experimental Animal Study.
Peter AI; Naidu EC; Akang E; Ogedengbe OO; Offor U; Rambharose S; Kalhapure R; Chuturgoon A; Govender T; Azu OO
Toxicol Res; 2018 Jul; 34(3):221-229. PubMed ID: 30057696
[TBL] [Abstract][Full Text] [Related]
19. ATP/ADP biosensor organoids for drug nephrotoxicity assessment.
Susa K; Kobayashi K; Galichon P; Matsumoto T; Tamura A; Hiratsuka K; Gupta NR; Yazdi IK; Bonventre JV; Morizane R
Front Cell Dev Biol; 2023; 11():1138504. PubMed ID: 36936695
[TBL] [Abstract][Full Text] [Related]
20. Comparative Analysis of the Physiological and Transport Functions of Various Sources of Renal Proximal Tubule Cells Under Static and Fluidic Conditions in PhysioMimix{trade mark, serif} T12 Platform.
Sakolish C; Moyer HL; Tsai HD; Ford LC; Dickey AN; Bajaj P; Villenave R; Hewitt P; Ferguson SS; Stanko J; Rusyn I
Drug Metab Dispos; 2024 Apr; ():. PubMed ID: 38626992
[No Abstract] [Full Text] [Related]
[Next] [New Search]