These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

76 related articles for article (PubMed ID: 21406348)

  • 1. Synthesis and cAMP-dependent phosphodiesterase inhibition of novel thiazoloquinazoline derivatives.
    Selvam TP; Kumar PV
    Acta Pharm; 2011 Mar; 61(1):103-13. PubMed ID: 21406348
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and SAR study of new phenylimidazole-pyrazolo[1,5-c]quinazolines as potent phosphodiesterase 10A inhibitors.
    Asproni B; Murineddu G; Pau A; Pinna GA; Langgård M; Christoffersen CT; Nielsen J; Kehler J
    Bioorg Med Chem; 2011 Jan; 19(1):642-9. PubMed ID: 21087867
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Spiroquinazolinones as novel, potent, and selective PDE7 inhibitors. Part 1.
    Lorthiois E; Bernardelli P; Vergne F; Oliveira C; Mafroud AK; Proust E; Heuze L; Moreau F; Idrissi M; Tertre A; Bertin B; Coupe M; Wrigglesworth R; Descours A; Soulard P; Berna P
    Bioorg Med Chem Lett; 2004 Sep; 14(18):4623-6. PubMed ID: 15324876
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and evaluation of quinazoline derivatives as phosphodiesterase 7 inhibitors.
    Sánchez AI; Martínez-Barrasa V; Burgos C; Vaquero JJ; Alvarez-Builla J; Terricabras E; Segarra V
    Bioorg Med Chem; 2013 Apr; 21(8):2370-2378. PubMed ID: 23454131
    [TBL] [Abstract][Full Text] [Related]  

  • 5. QSAR study of phosphodiesterase inhibitory activity of imidazo[2,1-b]-quinazolines: active site analysis.
    Prabhakar YS
    Drug Des Deliv; 1989 Dec; 5(2):81-91. PubMed ID: 2577989
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A new therapeutic approach in Parkinson's disease: some novel quinazoline derivatives as dual selective phosphodiesterase 1 inhibitors and anti-inflammatory agents.
    Laddha SS; Bhatnagar SP
    Bioorg Med Chem; 2009 Oct; 17(19):6796-802. PubMed ID: 19744861
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Studies on quinazolines and 1,2,4-benzothiadiazine 1,1-dioxides. 8.1, 2 synthesis and pharmacological evaluation of tricyclic fused quinazolines and 1,2,4-benzothiadiazine 1,1-dioxides as potential alpha1-adrenoceptor antagonists.
    Chern JW; Tao PL; Wang KC; Gutcait A; Liu SW; Yen MH; Chien SL; Rong JK
    J Med Chem; 1998 Aug; 41(17):3128-41. PubMed ID: 9703460
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis of 7-benzylamino-6-chloro-2-piperazino-4-pyrrolidinopteridine and novel derivatives free of positional isomers. Potent inhibitors of cAMP-specific phosphodiesterase and of malignant tumor cell growth.
    Merz KH; Marko D; Regiert T; Reiss G; Frank W; Eisenbrand G
    J Med Chem; 1998 Nov; 41(24):4733-43. PubMed ID: 9822544
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design and synthesis of novel substituted quinazoline derivatives as antileishmanial agents.
    Agarwal KC; Sharma V; Shakya N; Gupta S
    Bioorg Med Chem Lett; 2009 Sep; 19(18):5474-7. PubMed ID: 19692240
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Triazoloquinazolines as a novel class of phosphodiesterase 10A (PDE10A) inhibitors.
    Kehler J; Ritzen A; Langgård M; Petersen SL; Farah MM; Bundgaard C; Christoffersen CT; Nielsen J; Kilburn JP
    Bioorg Med Chem Lett; 2011 Jun; 21(12):3738-42. PubMed ID: 21602043
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Discovery of a series of 6,7-dimethoxy-4-pyrrolidylquinazoline PDE10A inhibitors.
    Chappie TA; Humphrey JM; Allen MP; Estep KG; Fox CB; Lebel LA; Liras S; Marr ES; Menniti FS; Pandit J; Schmidt CJ; Tu M; Williams RD; Yang FV
    J Med Chem; 2007 Jan; 50(2):182-5. PubMed ID: 17228859
    [TBL] [Abstract][Full Text] [Related]  

  • 12. 6-Nitrobenzimidazole derivatives: potential phosphodiesterase inhibitors: synthesis and structure-activity relationship.
    Khan KM; Shah Z; Ahmad VU; Ambreen N; Khan M; Taha M; Rahim F; Noreen S; Perveen S; Choudhary MI; Voelter W
    Bioorg Med Chem; 2012 Feb; 20(4):1521-6. PubMed ID: 22264761
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of human cardiac cyclic AMP-phosphodiesterases by R 80122, a new selective cyclic AMP-phosphodiesterase III inhibitor: a comparison with other cardiotonic compounds.
    de Cheffoy de Courcelles D; de Loore K; Freyne E; Janssen PA
    J Pharmacol Exp Ther; 1992 Oct; 263(1):6-14. PubMed ID: 1328613
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design, synthesis, and pharmacological characterization of some 2-substituted-3-phenyl-quinazolin-4(3H)-one derivatives as phosphodiesterase inhibitors.
    Amin KM; Hegazy GH; George RF; Ibrahim NR; Mohamed NM
    Arch Pharm (Weinheim); 2021 Sep; 354(9):e2100051. PubMed ID: 33977557
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and biological evaluation of substituted 6-alkynyl-4-anilinoquinazoline derivatives as potent EGFR inhibitors.
    Liu LT; Yuan TT; Liu HH; Chen SF; Wu YT
    Bioorg Med Chem Lett; 2007 Nov; 17(22):6373-7. PubMed ID: 17889528
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis, characterization, and anthelmintic activity of novel 6,7,8,9-tetrahydro-5H-5-phenyl-2-benzylidine-3-substituted hydrazino thiazolo (2,3-b) quinazoline derivatives and analogues.
    Selvam TP; Kumar PV
    Drug Discov Ther; 2010 Dec; 4(6):392-8. PubMed ID: 22491303
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Spiroquinazolinones as novel, potent, and selective PDE7 inhibitors. Part 2: Optimization of 5,8-disubstituted derivatives.
    Bernardelli P; Lorthiois E; Vergne F; Oliveira C; Mafroud AK; Proust E; Pham N; Ducrot P; Moreau F; Idrissi M; Tertre A; Bertin B; Coupe M; Chevalier E; Descours A; Berlioz-Seux F; Berna P; Li M
    Bioorg Med Chem Lett; 2004 Sep; 14(18):4627-31. PubMed ID: 15324877
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The discovery and synthesis of highly potent subtype selective phosphodiesterase 4D inhibitors.
    Aspiotis R; Deschênes D; Dubé D; Girard Y; Huang Z; Laliberté F; Liu S; Papp R; Nicholson DW; Young RN
    Bioorg Med Chem Lett; 2010 Sep; 20(18):5502-5. PubMed ID: 20709547
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and evaluation of novel rutaecarpine derivatives and related alkaloids derivatives as selective acetylcholinesterase inhibitors.
    Wang B; Mai YC; Li Y; Hou JQ; Huang SL; Ou TM; Tan JH; An LK; Li D; Gu LQ; Huang ZS
    Eur J Med Chem; 2010 Apr; 45(4):1415-23. PubMed ID: 20079560
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 2,3-Dihydro-9H-isoxazolo[3,2-b]quinazolin-9-ones and 3,4-dihydro-(1,2)-oxazino [3,2-b]quinazolin-10(2H)-ones.
    Reisner DB; Ludwig BJ; Simon E; Dejneka T; Sofia RD
    Arzneimittelforschung; 1977; 27(4):766-70. PubMed ID: 301391
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 4.