BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

554 related articles for article (PubMed ID: 21406388)

  • 1. Crohn's disease-associated ATG16L1 polymorphism modulates pro-inflammatory cytokine responses selectively upon activation of NOD2.
    Plantinga TS; Crisan TO; Oosting M; van de Veerdonk FL; de Jong DJ; Philpott DJ; van der Meer JW; Girardin SE; Joosten LA; Netea MG
    Gut; 2011 Sep; 60(9):1229-35. PubMed ID: 21406388
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Engagement of NOD2 has a dual effect on proIL-1beta mRNA transcription and secretion of bioactive IL-1beta.
    Ferwerda G; Kramer M; de Jong D; Piccini A; Joosten LA; Devesaginer I; Girardin SE; Adema GJ; van der Meer JW; Kullberg BJ; Rubartelli A; Netea MG
    Eur J Immunol; 2008 Jan; 38(1):184-91. PubMed ID: 18157816
    [TBL] [Abstract][Full Text] [Related]  

  • 3. NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation.
    Cooney R; Baker J; Brain O; Danis B; Pichulik T; Allan P; Ferguson DJ; Campbell BJ; Jewell D; Simmons A
    Nat Med; 2010 Jan; 16(1):90-7. PubMed ID: 19966812
    [TBL] [Abstract][Full Text] [Related]  

  • 4. NOD2 mediates anti-inflammatory signals induced by TLR2 ligands: implications for Crohn's disease.
    Netea MG; Kullberg BJ; de Jong DJ; Franke B; Sprong T; Naber TH; Drenth JP; Van der Meer JW
    Eur J Immunol; 2004 Jul; 34(7):2052-9. PubMed ID: 15214053
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The protein ATG16L1 suppresses inflammatory cytokines induced by the intracellular sensors Nod1 and Nod2 in an autophagy-independent manner.
    Sorbara MT; Ellison LK; Ramjeet M; Travassos LH; Jones NL; Girardin SE; Philpott DJ
    Immunity; 2013 Nov; 39(5):858-73. PubMed ID: 24238340
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production.
    Saitoh T; Fujita N; Jang MH; Uematsu S; Yang BG; Satoh T; Omori H; Noda T; Yamamoto N; Komatsu M; Tanaka K; Kawai T; Tsujimura T; Takeuchi O; Yoshimori T; Akira S
    Nature; 2008 Nov; 456(7219):264-8. PubMed ID: 18849965
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Impaired autophagy of an intracellular pathogen induced by a Crohn's disease associated ATG16L1 variant.
    Kuballa P; Huett A; Rioux JD; Daly MJ; Xavier RJ
    PLoS One; 2008; 3(10):e3391. PubMed ID: 18852889
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synergy between TLR9 and NOD2 innate immune responses is lost in genetic Crohn's disease.
    van Heel DA; Ghosh S; Hunt KA; Mathew CG; Forbes A; Jewell DP; Playford RJ
    Gut; 2005 Nov; 54(11):1553-7. PubMed ID: 15928043
    [TBL] [Abstract][Full Text] [Related]  

  • 9. ATG16L1 and NOD2 interact in an autophagy-dependent antibacterial pathway implicated in Crohn's disease pathogenesis.
    Homer CR; Richmond AL; Rebert NA; Achkar JP; McDonald C
    Gastroenterology; 2010 Nov; 139(5):1630-41, 1641.e1-2. PubMed ID: 20637199
    [TBL] [Abstract][Full Text] [Related]  

  • 10. NOD2 and ATG16L1 polymorphisms affect monocyte responses in Crohn's disease.
    Glubb DM; Gearry RB; Barclay ML; Roberts RL; Pearson J; Keenan JI; McKenzie J; Bentley RW
    World J Gastroenterol; 2011 Jun; 17(23):2829-37. PubMed ID: 21734790
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Expression of TRAF6 and pro-inflammatory cytokines through activation of TLR2, TLR4, NOD1, and NOD2 in human periodontal ligament fibroblasts.
    Tang L; Zhou XD; Wang Q; Zhang L; Wang Y; Li XY; Huang DM
    Arch Oral Biol; 2011 Oct; 56(10):1064-72. PubMed ID: 21457942
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Classification of genetic profiles of Crohn's disease: a focus on the ATG16L1 gene.
    Grant SF; Baldassano RN; Hakonarson H
    Expert Rev Mol Diagn; 2008 Mar; 8(2):199-207. PubMed ID: 18366306
    [TBL] [Abstract][Full Text] [Related]  

  • 13. NOD2 engagement induces proinflammatory cytokine production, but not apoptosis, in leukocytes isolated from patients with Crohn's disease.
    Bodar E; Netea MG; de Jong DJ; Kullberg BJ; Joosten LA; Van der Meer JW
    Eur Cytokine Netw; 2008 Dec; 19(4):185-9. PubMed ID: 19103524
    [TBL] [Abstract][Full Text] [Related]  

  • 14. NOD2 3020insC mutation and the pathogenesis of Crohn's disease: impaired IL-1beta production points to a loss-of-function phenotype.
    Netea MG; Ferwerda G; de Jong DJ; Girardin SE; Kullberg BJ; van der Meer JW
    Neth J Med; 2005 Sep; 63(8):305-8. PubMed ID: 16186640
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Autophagy genes variants and paediatric Crohn's disease phenotype: a single-centre experience.
    Strisciuglio C; Auricchio R; Martinelli M; Staiano A; Giugliano FP; Andreozzi M; De Rosa M; Giannetti E; Gianfrani C; Izzo P; Troncone R; Miele E
    Dig Liver Dis; 2014 Jun; 46(6):512-7. PubMed ID: 24656308
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The Crohn's disease-associated polymorphism in ATG16L1 (rs2241880) reduces SHIP gene expression and activity in human subjects.
    Ngoh EN; Brugger HK; Monajemi M; Menzies SC; Hirschfeld AF; Del Bel KL; Jacobson K; Lavoie PM; Turvey SE; Sly LM
    Genes Immun; 2015 Oct; 16(7):452-61. PubMed ID: 26226011
    [TBL] [Abstract][Full Text] [Related]  

  • 17. [Barrier- and autophagic functions of the intestinal epithelia: role of disturbances in the pathogenesis of Crohn's disease].
    Lapis K
    Orv Hetil; 2010 Oct; 151(40):1645-55. PubMed ID: 20860961
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Genetic susceptibility to increased bacterial translocation influences the response to biological therapy in patients with Crohn's disease.
    Gutiérrez A; Scharl M; Sempere L; Holler E; Zapater P; Almenta I; González-Navajas JM; Such J; Wiest R; Rogler G; Francés R
    Gut; 2014 Feb; 63(2):272-80. PubMed ID: 23376290
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Bacterial invasion: linking autophagy and innate immunity.
    Galluzzi L; Kepp O; Zitvogel L; Kroemer G
    Curr Biol; 2010 Feb; 20(3):R106-8. PubMed ID: 20144769
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Innate immune defence: NOD2 and autophagy in the pathogenesis of Crohn's disease.
    Hruz P; Eckmann L
    Swiss Med Wkly; 2010; 140():w13135. PubMed ID: 21213148
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 28.