These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

156 related articles for article (PubMed ID: 21409387)

  • 1. Helix-mediated protein--protein interactions as targets for intervention using foldamers.
    Edwards TA; Wilson AJ
    Amino Acids; 2011 Aug; 41(3):743-54. PubMed ID: 21409387
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Comprehensive peptidomimetic libraries targeting protein-protein interactions.
    Whitby LR; Boger DL
    Acc Chem Res; 2012 Oct; 45(10):1698-709. PubMed ID: 22799570
    [TBL] [Abstract][Full Text] [Related]  

  • 3. α-Helix-Mimicking Sulfono-γ-AApeptide Inhibitors for p53-MDM2/MDMX Protein-Protein Interactions.
    Sang P; Shi Y; Lu J; Chen L; Yang L; Borcherds W; Abdulkadir S; Li Q; Daughdrill G; Chen J; Cai J
    J Med Chem; 2020 Feb; 63(3):975-986. PubMed ID: 31971801
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural basis for high-affinity peptide inhibition of p53 interactions with MDM2 and MDMX.
    Pazgier M; Liu M; Zou G; Yuan W; Li C; Li C; Li J; Monbo J; Zella D; Tarasov SG; Lu W
    Proc Natl Acad Sci U S A; 2009 Mar; 106(12):4665-70. PubMed ID: 19255450
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Isolation of a peptide containing d-amino acid residues that inhibits the α-helix-mediated p53-MDM2 interaction from a one-bead one-compound library.
    Morimoto J; Hosono Y; Sando S
    Bioorg Med Chem Lett; 2018 Feb; 28(3):231-234. PubMed ID: 29326019
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Functional profiling of p53-binding sites in Hdm2 and Hdmx using a genetic selection system.
    Datta S; Bucks ME; Koley D; Lim PX; Savinov SN
    Bioorg Med Chem; 2010 Aug; 18(16):6099-108. PubMed ID: 20638853
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A stapled p53 helix overcomes HDMX-mediated suppression of p53.
    Bernal F; Wade M; Godes M; Davis TN; Whitehead DG; Kung AL; Wahl GM; Walensky LD
    Cancer Cell; 2010 Nov; 18(5):411-22. PubMed ID: 21075307
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Elaboration of Non-naturally Occurring Helical Tripeptides as p53-MDM2/MDMX Interaction Inhibitors.
    Su A; Tabata Y; Aoki K; Sada A; Ohki R; Nagatoishi S; Tsumoto K; Wang S; Otani Y; Ohwada T
    Chem Pharm Bull (Tokyo); 2021 Jul; 69(7):681-692. PubMed ID: 33952867
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design of libraries targeting protein-protein interfaces.
    Fry D; Huang KS; Di Lello P; Mohr P; Müller K; So SS; Harada T; Stahl M; Vu B; Mauser H
    ChemMedChem; 2013 May; 8(5):726-32. PubMed ID: 23436619
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Molecular basis for the inhibition of p53 by Mdmx.
    Popowicz GM; Czarna A; Rothweiler U; Szwagierczak A; Krajewski M; Weber L; Holak TA
    Cell Cycle; 2007 Oct; 6(19):2386-92. PubMed ID: 17938582
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Sulfono-γ-AApeptides as Helical Mimetics: Crystal Structures and Applications.
    Sang P; Shi Y; Huang B; Xue S; Odom T; Cai J
    Acc Chem Res; 2020 Oct; 53(10):2425-2442. PubMed ID: 32940995
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Discovery of α-helix-mimicking sulfono-γ-AApeptides as p53-MDM2 inhibitors.
    Shi Y; Sang P; Cai J
    Future Med Chem; 2021 Jun; 13(12):1021-1023. PubMed ID: 33906432
    [No Abstract]   [Full Text] [Related]  

  • 13. Structural basis for the conserved binding mechanism of MDM2-inhibiting peptides and anti-apoptotic Bcl-2 family proteins.
    Lee MS; Ha JH; Yoon HS; Lee CK; Chi SW
    Biochem Biophys Res Commun; 2014 Feb; 445(1):120-5. PubMed ID: 24491548
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Stapled peptides in the p53 pathway: computer simulations reveal novel interactions of the staples with the target protein.
    Joseph TL; Lane D; Verma CS
    Cell Cycle; 2010 Nov; 9(22):4560-8. PubMed ID: 21088491
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structure-activity studies of Mdm2/Mdm4-binding stapled peptides comprising non-natural amino acids.
    Chee SMQ; Wongsantichon J; Siau J; Thean D; Ferrer F; Robinson RC; Lane DP; Brown CJ; Ghadessy FJ
    PLoS One; 2017; 12(12):e0189379. PubMed ID: 29228061
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Targeting of p53 peptide analogues to anti-apoptotic Bcl-2 family proteins as revealed by NMR spectroscopy.
    Shin JS; Ha JH; Chi SW
    Biochem Biophys Res Commun; 2014 Jan; 443(3):882-7. PubMed ID: 24342622
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Interaction of regulators Mdm2 and Mdmx with transcription factors p53, p63 and p73.
    Zdzalik M; Pustelny K; Kedracka-Krok S; Huben K; Pecak A; Wladyka B; Jankowski S; Dubin A; Potempa J; Dubin G
    Cell Cycle; 2010 Nov; 9(22):4584-91. PubMed ID: 21088494
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Using a beta-hairpin to mimic an alpha-helix: cyclic peptidomimetic inhibitors of the p53-HDM2 protein-protein interaction.
    Fasan R; Dias RL; Moehle K; Zerbe O; Vrijbloed JW; Obrecht D; Robinson JA
    Angew Chem Int Ed Engl; 2004 Apr; 43(16):2109-12. PubMed ID: 15083458
    [No Abstract]   [Full Text] [Related]  

  • 19. Identification of small molecules affecting p53-MDM2/MDMX interaction by fluorescence polarization.
    Zhang Q; Lu H
    Methods Mol Biol; 2013; 962():95-111. PubMed ID: 23150440
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Peptide activators of the p53 tumor suppressor.
    Zhan C; Lu W
    Curr Pharm Des; 2011; 17(6):603-9. PubMed ID: 21391910
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.