442 related articles for article (PubMed ID: 21409565)
1. EMSY overexpression disrupts the BRCA2/RAD51 pathway in the DNA-damage response: implications for chromosomal instability/recombination syndromes as checkpoint diseases.
Cousineau I; Belmaaza A
Mol Genet Genomics; 2011 Apr; 285(4):325-40. PubMed ID: 21409565
[TBL] [Abstract][Full Text] [Related]
2. Functional characterization of EMSY gene amplification in human cancers.
Wilkerson PM; Dedes KJ; Wetterskog D; Mackay A; Lambros MB; Mansour M; Frankum J; Lord CJ; Natrajan R; Ashworth A; Reis-Filho JS
J Pathol; 2011 Sep; 225(1):29-42. PubMed ID: 21735447
[TBL] [Abstract][Full Text] [Related]
3. Breast cancer-associated missense mutants of the PALB2 WD40 domain, which directly binds RAD51C, RAD51 and BRCA2, disrupt DNA repair.
Park JY; Singh TR; Nassar N; Zhang F; Freund M; Hanenberg H; Meetei AR; Andreassen PR
Oncogene; 2014 Oct; 33(40):4803-12. PubMed ID: 24141787
[TBL] [Abstract][Full Text] [Related]
4. PALB2 regulates recombinational repair through chromatin association and oligomerization.
Sy SM; Huen MS; Zhu Y; Chen J
J Biol Chem; 2009 Jul; 284(27):18302-10. PubMed ID: 19423707
[TBL] [Abstract][Full Text] [Related]
5. EMSY links the BRCA2 pathway to sporadic breast and ovarian cancer.
Hughes-Davies L; Huntsman D; Ruas M; Fuks F; Bye J; Chin SF; Milner J; Brown LA; Hsu F; Gilks B; Nielsen T; Schulzer M; Chia S; Ragaz J; Cahn A; Linger L; Ozdag H; Cattaneo E; Jordanova ES; Schuuring E; Yu DS; Venkitaraman A; Ponder B; Doherty A; Aparicio S; Bentley D; Theillet C; Ponting CP; Caldas C; Kouzarides T
Cell; 2003 Nov; 115(5):523-35. PubMed ID: 14651845
[TBL] [Abstract][Full Text] [Related]
6. The EMSY threonine 207 phospho-site is required for EMSYdriven suppression of DNA damage repair.
Jelinic P; Eccles LA; Tseng J; Cybulska P; Wielgos M; Powell SN; Levine DA
Oncotarget; 2017 Feb; 8(8):13792-13804. PubMed ID: 28099152
[TBL] [Abstract][Full Text] [Related]
7. Plasticity of BRCA2 function in homologous recombination: genetic interactions of the PALB2 and DNA binding domains.
Siaud N; Barbera MA; Egashira A; Lam I; Christ N; Schlacher K; Xia B; Jasin M
PLoS Genet; 2011 Dec; 7(12):e1002409. PubMed ID: 22194698
[TBL] [Abstract][Full Text] [Related]
8. Purified human BRCA2 stimulates RAD51-mediated recombination.
Jensen RB; Carreira A; Kowalczykowski SC
Nature; 2010 Oct; 467(7316):678-83. PubMed ID: 20729832
[TBL] [Abstract][Full Text] [Related]
9. PALB2 functionally connects the breast cancer susceptibility proteins BRCA1 and BRCA2.
Zhang F; Fan Q; Ren K; Andreassen PR
Mol Cancer Res; 2009 Jul; 7(7):1110-8. PubMed ID: 19584259
[TBL] [Abstract][Full Text] [Related]
10. Therapeutic exploitation of tumor cell defects in homologous recombination.
Powell SN; Kachnic LA
Anticancer Agents Med Chem; 2008 May; 8(4):448-60. PubMed ID: 18473729
[TBL] [Abstract][Full Text] [Related]
11. SPOP promotes transcriptional expression of DNA repair and replication factors to prevent replication stress and genomic instability.
Hjorth-Jensen K; Maya-Mendoza A; Dalgaard N; Sigurðsson JO; Bartek J; Iglesias-Gato D; Olsen JV; Flores-Morales A
Nucleic Acids Res; 2018 Oct; 46(18):9484-9495. PubMed ID: 30124983
[TBL] [Abstract][Full Text] [Related]
12. Genomic instability of human mammary epithelial cells overexpressing a truncated form of EMSY.
Raouf A; Brown L; Vrcelj N; To K; Kwok W; Huntsman D; Eaves CJ
J Natl Cancer Inst; 2005 Sep; 97(17):1302-6. PubMed ID: 16145051
[TBL] [Abstract][Full Text] [Related]
13. BRCA2 regulates homologous recombination in response to DNA damage: implications for genome stability and carcinogenesis.
Abaji C; Cousineau I; Belmaaza A
Cancer Res; 2005 May; 65(10):4117-25. PubMed ID: 15899802
[TBL] [Abstract][Full Text] [Related]
14. The protein kinase Akt1 regulates the interferon response through phosphorylation of the transcriptional repressor EMSY.
Ezell SA; Polytarchou C; Hatziapostolou M; Guo A; Sanidas I; Bihani T; Comb MJ; Sourvinos G; Tsichlis PN
Proc Natl Acad Sci U S A; 2012 Mar; 109(10):E613-21. PubMed ID: 22315412
[TBL] [Abstract][Full Text] [Related]
15. The carboxyl terminus of Brca2 links the disassembly of Rad51 complexes to mitotic entry.
Ayoub N; Rajendra E; Su X; Jeyasekharan AD; Mahen R; Venkitaraman AR
Curr Biol; 2009 Jul; 19(13):1075-85. PubMed ID: 19540122
[TBL] [Abstract][Full Text] [Related]
16. A phosphorylation-deubiquitination cascade regulates the BRCA2-RAD51 axis in homologous recombination.
Luo K; Li L; Li Y; Wu C; Yin Y; Chen Y; Deng M; Nowsheen S; Yuan J; Lou Z
Genes Dev; 2016 Dec; 30(23):2581-2595. PubMed ID: 27941124
[TBL] [Abstract][Full Text] [Related]
17. BRCA2 chaperones RAD51 to single molecules of RPA-coated ssDNA.
Bell JC; Dombrowski CC; Plank JL; Jensen RB; Kowalczykowski SC
Proc Natl Acad Sci U S A; 2023 Apr; 120(14):e2221971120. PubMed ID: 36976771
[TBL] [Abstract][Full Text] [Related]
18. Two replication fork maintenance pathways fuse inverted repeats to rearrange chromosomes.
Hu L; Kim TM; Son MY; Kim SA; Holland CL; Tateishi S; Kim DH; Yew PR; Montagna C; Dumitrache LC; Hasty P
Nature; 2013 Sep; 501(7468):569-72. PubMed ID: 24013173
[TBL] [Abstract][Full Text] [Related]
19. Fanconi anemia complementation group D2 (FANCD2) functions independently of BRCA2- and RAD51-associated homologous recombination in response to DNA damage.
Ohashi A; Zdzienicka MZ; Chen J; Couch FJ
J Biol Chem; 2005 Apr; 280(15):14877-83. PubMed ID: 15671039
[TBL] [Abstract][Full Text] [Related]
20. Clarifying the role of EMSY in DNA repair in ovarian cancer.
Kondrashova O; Scott CL
Cancer; 2019 Aug; 125(16):2720-2724. PubMed ID: 31154666
[No Abstract] [Full Text] [Related]
[Next] [New Search]
