These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

88 related articles for article (PubMed ID: 21411321)

  • 1. Design, synthesis and structure-activity relationships of (indo-3-yl) heterocyclic derivatives as agonists of the CB1 receptor. Discovery of a clinical candidate.
    Ratcliffe P; Adam JM; Baker J; Bursi R; Campbell R; Clark JK; Cottney JE; Deehan M; Easson AM; Ecker D; Edwards D; Epemolu O; Evans L; Fields R; Francis S; Harradine P; Jeremiah F; Kiyoi T; McArthur D; Morrison A; Passier P; Pick J; Schnabel PG; Schulz J; Steinbrede H; Walker G; Westwood P; Wishart G; Udo de Haes J
    Bioorg Med Chem Lett; 2011 Apr; 21(8):2541-6. PubMed ID: 21411321
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design, synthesis, and structure-activity relationships of indole-3-heterocycles as agonists of the CB1 receptor.
    Morrison AJ; Adam JM; Baker JA; Campbell RA; Clark JK; Cottney JE; Deehan M; Easson AM; Fields R; Francis S; Jeremiah F; Keddie N; Kiyoi T; McArthur DR; Meyer K; Ratcliffe PD; Schulz J; Wishart G; Yoshiizumi K
    Bioorg Med Chem Lett; 2011 Jan; 21(1):506-9. PubMed ID: 21075630
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design, synthesis, and structure-activity relationship study of conformationally constrained analogs of indole-3-carboxamides as novel CB1 cannabinoid receptor agonists.
    Kiyoi T; York M; Francis S; Edwards D; Walker G; Houghton AK; Cottney JE; Baker J; Adam JM
    Bioorg Med Chem Lett; 2010 Aug; 20(16):4918-21. PubMed ID: 20634067
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The discovery of novel indole-2-carboxamides as cannabinoid CB(1) receptor antagonists.
    Cowley PM; Baker J; Barn DR; Buchanan KI; Carlyle I; Clark JK; Clarkson TR; Deehan M; Edwards D; Goodwin RR; Jaap D; Kiyoi Y; Mort C; Palin R; Prosser A; Walker G; Ward N; Wishart G; Young T
    Bioorg Med Chem Lett; 2011 Jan; 21(1):497-501. PubMed ID: 21075628
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Discovery of potent and orally bioavailable heterocycle-based cannabinoid CB1 receptor agonists.
    Kiyoi T; Adam JM; Clark JK; Davies K; Easson AM; Edwards D; Feilden H; Fields R; Francis S; Jeremiah F; McArthur D; Morrison AJ; Prosser A; Ratcliffe PD; Schulz J; Wishart G; Baker J; Campbell R; Cottney JE; Deehan M; Epemolu O; Evans L
    Bioorg Med Chem Lett; 2011 Mar; 21(6):1748-53. PubMed ID: 21316962
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Low brain penetrant CB1 receptor agonists for the treatment of neuropathic pain.
    Adam JM; Clark JK; Davies K; Everett K; Fields R; Francis S; Jeremiah F; Kiyoi T; Maidment M; Morrison A; Ratcliffe P; Prosser A; Schulz J; Wishart G; Baker J; Boyce S; Campbell R; Cottney JE; Deehan M; Martin I
    Bioorg Med Chem Lett; 2012 Apr; 22(8):2932-7. PubMed ID: 22421020
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification and hit-to-lead optimization of a novel class of CB1 antagonists.
    Letourneau JJ; Jokiel P; Olson J; Riviello CM; Ho KK; McAleer L; Yang J; Swanson RN; Baker J; Cowley P; Edwards D; Ward N; Ohlmeyer MH; Webb ML
    Bioorg Med Chem Lett; 2010 Sep; 20(18):5449-53. PubMed ID: 20719511
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and cannabinoid activity of 1-substituted-indole-3-oxadiazole derivatives: novel agonists for the CB1 receptor.
    Moloney GP; Angus JA; Robertson AD; Stoermer MJ; Robinson M; Wright CE; McRae K; Christopoulos A
    Eur J Med Chem; 2008 Mar; 43(3):513-39. PubMed ID: 17582659
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design, synthesis, and structure-activity relationship study of bicyclic piperazine analogs of indole-3-carboxamides as novel cannabinoid CB1 receptor agonists.
    Moir EM; Yoshiizumi K; Cairns J; Cowley P; Ferguson M; Jeremiah F; Kiyoi T; Morphy R; Tierney J; Wishart G; York M; Baker J; Cottney JE; Houghton AK; McPhail P; Osprey A; Walker G; Adam JM
    Bioorg Med Chem Lett; 2010 Dec; 20(24):7327-30. PubMed ID: 21074434
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and SAR of selective benzothiophene, benzofuran, and indole-based peroxisome proliferator-activated receptor delta agonists.
    Filzen GF; Bratton L; Cheng XM; Erasga N; Geyer A; Lee C; Lu G; Pulaski J; Sorenson RJ; Unangst PC; Trivedi BK; Xu X
    Bioorg Med Chem Lett; 2007 Jul; 17(13):3630-5. PubMed ID: 17512197
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design, synthesis and biological evaluation of piperazine analogues as CB1 cannabinoid receptor ligands.
    Song KS; Lee SH; Chun HJ; Kim JY; Jung ME; Ahn K; Kim SU; Kim J; Lee J
    Bioorg Med Chem; 2008 Apr; 16(7):4035-51. PubMed ID: 18243711
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Potent cannabinergic indole analogues as radioiodinatable brain imaging agents for the CB1 cannabinoid receptor.
    Deng H; Gifford AN; Zvonok AM; Cui G; Li X; Fan P; Deschamps JR; Flippen-Anderson JL; Gatley SJ; Makriyannis A
    J Med Chem; 2005 Oct; 48(20):6386-92. PubMed ID: 16190764
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Novel indole and azaindole (pyrrolopyridine) cannabinoid (CB) receptor agonists: design, synthesis, structure-activity relationships, physicochemical properties and biological activity.
    Blaazer AR; Lange JH; van der Neut MA; Mulder A; den Boon FS; Werkman TR; Kruse CG; Wadman WJ
    Eur J Med Chem; 2011 Oct; 46(10):5086-98. PubMed ID: 21885167
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Discovery and optimization of novel purines as potent and selective CB2 agonists.
    Hollinshead SP; Astles PC; Chambers MG; Johnson MP; Palmer J; Tidwell MW
    Bioorg Med Chem Lett; 2012 Aug; 22(15):4962-6. PubMed ID: 22765893
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Furo[2,3-b]pyridine-based cannabinoid-1 receptor inverse agonists: synthesis and biological evaluation. Part 1.
    Debenham JS; Madsen-Duggan CB; Toupence RB; Walsh TF; Wang J; Tong X; Kumar S; Lao J; Fong TM; Xiao JC; Huang CR; Shen CP; Feng Y; Marsh DJ; Stribling DS; Shearman LP; Strack AM; Goulet MT
    Bioorg Med Chem Lett; 2010 Feb; 20(4):1448-52. PubMed ID: 20096577
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Novel pyridine derivatives as potent and selective CB2 cannabinoid receptor agonists.
    Chu GH; Saeui CT; Worm K; Weaver DG; Goodman AJ; Broadrup RL; Cassel JA; DeHaven RN; LaBuda CJ; Koblish M; Brogdon B; Smith S; Le Bourdonnec B; Dolle RE
    Bioorg Med Chem Lett; 2009 Oct; 19(20):5931-5. PubMed ID: 19736007
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Indol-3-ylcycloalkyl ketones: effects of N1 substituted indole side chain variations on CB(2) cannabinoid receptor activity.
    Frost JM; Dart MJ; Tietje KR; Garrison TR; Grayson GK; Daza AV; El-Kouhen OF; Yao BB; Hsieh GC; Pai M; Zhu CZ; Chandran P; Meyer MD
    J Med Chem; 2010 Jan; 53(1):295-315. PubMed ID: 19921781
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Discovery of S-444823, a potent CB1/CB2 dual agonist as an antipruritic agent.
    Odan M; Ishizuka N; Hiramatsu Y; Inagaki M; Hashizume H; Fujii Y; Mitsumori S; Morioka Y; Soga M; Deguchi M; Yasui K; Arimura A
    Bioorg Med Chem Lett; 2012 Apr; 22(8):2898-901. PubMed ID: 22421019
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A new orally bioavailable dual adenosine A2B/A3 receptor antagonist with therapeutic potential.
    Press NJ; Taylor RJ; Fullerton JD; Tranter P; McCarthy C; Keller TH; Brown L; Cheung R; Christie J; Haberthuer S; Hatto JD; Keenan M; Mercer MK; Press NE; Sahri H; Tuffnell AR; Tweed M; Fozard JR
    Bioorg Med Chem Lett; 2005 Jun; 15(12):3081-5. PubMed ID: 15876531
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and evaluation of dibenzothiazepines: a novel class of selective cannabinoid-1 receptor inverse agonists.
    Pettersson H; Bülow A; Ek F; Jensen J; Ottesen LK; Fejzic A; Ma JN; Del Tredici AL; Currier EA; Gardell LR; Tabatabaei A; Craig D; McFarland K; Ott TR; Piu F; Burstein ES; Olsson R
    J Med Chem; 2009 Apr; 52(7):1975-82. PubMed ID: 19338356
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.