BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

180 related articles for article (PubMed ID: 21413014)

  • 1. Hemin, an iron-binding porphyrin, inhibits HIF-1α induction through its binding with heat shock protein 90.
    Lee JM; Lee WH; Kay HY; Kim ES; Moon A; Kim SG
    Int J Cancer; 2012 Feb; 130(3):716-27. PubMed ID: 21413014
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Oltipraz and dithiolethione congeners inhibit hypoxia-inducible factor-1alpha activity through p70 ribosomal S6 kinase-1 inhibition and H2O2-scavenging effect.
    Lee WH; Kim YW; Choi JH; Brooks SC; Lee MO; Kim SG
    Mol Cancer Ther; 2009 Oct; 8(10):2791-802. PubMed ID: 19789218
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A group of novel HIF-1α inhibitors, glyceollins, blocks HIF-1α synthesis and decreases its stability via inhibition of the PI3K/AKT/mTOR pathway and Hsp90 binding.
    Lee SH; Jee JG; Bae JS; Liu KH; Lee YM
    J Cell Physiol; 2015 Apr; 230(4):853-62. PubMed ID: 25204544
    [TBL] [Abstract][Full Text] [Related]  

  • 4. C-Terminal HSP90 Inhibitors Block the HIF-1 Hypoxic Response by Degrading HIF-1α through the Oxygen-Dependent Degradation Pathway.
    Kataria N; Martinez CA; Kerr B; Zaiter SS; Morgan M; McAlpine SR; Cook KM
    Cell Physiol Biochem; 2019; 53(3):480-495. PubMed ID: 31486323
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Wogonin inhibits tumor angiogenesis via degradation of HIF-1α protein.
    Song X; Yao J; Wang F; Zhou M; Zhou Y; Wang H; Wei L; Zhao L; Li Z; Lu N; Guo Q
    Toxicol Appl Pharmacol; 2013 Sep; 271(2):144-55. PubMed ID: 23707765
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effects of geldanamycin on HIF-1alpha mediated angiogenesis and invasion in prostate cancer cells.
    Alqawi O; Moghaddas M; Singh G
    Prostate Cancer Prostatic Dis; 2006; 9(2):126-35. PubMed ID: 16432534
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Degradation of HIF-1alpha under hypoxia combined with induction of Hsp90 polyubiquitination in cancer cells by hypericin: a unique cancer therapy.
    Barliya T; Mandel M; Livnat T; Weinberger D; Lavie G
    PLoS One; 2011; 6(9):e22849. PubMed ID: 21949677
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Effects of 12 metal ions on iron regulatory protein 1 (IRP-1) and hypoxia-inducible factor-1 alpha (HIF-1alpha) and HIF-regulated genes.
    Li Q; Chen H; Huang X; Costa M
    Toxicol Appl Pharmacol; 2006 Jun; 213(3):245-55. PubMed ID: 16386771
    [TBL] [Abstract][Full Text] [Related]  

  • 9. AT-533, a novel Hsp90 inhibitor, inhibits breast cancer growth and HIF-1α/VEGF/VEGFR-2-mediated angiogenesis in vitro and in vivo.
    Zhang PC; Liu X; Li MM; Ma YY; Sun HT; Tian XY; Wang Y; Liu M; Fu LS; Wang YF; Chen HY; Liu Z
    Biochem Pharmacol; 2020 Feb; 172():113771. PubMed ID: 31863779
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hypoxia-inducible factor-1α inhibition by a pyrrolopyrazine metabolite of oltipraz as a consequence of microRNAs 199a-5p and 20a induction.
    Kang SG; Lee WH; Lee YH; Lee YS; Kim SG
    Carcinogenesis; 2012 Mar; 33(3):661-9. PubMed ID: 22223846
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Induction of the hypoxia-inducible factor system by low levels of heat shock protein 90 inhibitors.
    Ibrahim NO; Hahn T; Franke C; Stiehl DP; Wirthner R; Wenger RH; Katschinski DM
    Cancer Res; 2005 Dec; 65(23):11094-100. PubMed ID: 16322259
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Bcl-2 regulates HIF-1alpha protein stabilization in hypoxic melanoma cells via the molecular chaperone HSP90.
    Trisciuoglio D; Gabellini C; Desideri M; Ziparo E; Zupi G; Del Bufalo D
    PLoS One; 2010 Jul; 5(7):e11772. PubMed ID: 20668552
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Heat shock protein 90 promotes epithelial to mesenchymal transition, invasion, and migration in colorectal cancer.
    Nagaraju GP; Long TE; Park W; Landry JC; Taliaferro-Smith L; Farris AB; Diaz R; El-Rayes BF
    Mol Carcinog; 2015 Oct; 54(10):1147-58. PubMed ID: 24861206
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Antiangiogenic effects of a novel synthetic curcumin analogue in pancreatic cancer.
    Nagaraju GP; Zhu S; Ko JE; Ashritha N; Kandimalla R; Snyder JP; Shoji M; El-Rayes BF
    Cancer Lett; 2015 Feb; 357(2):557-65. PubMed ID: 25497868
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Sestrin2 inhibits hypoxia-inducible factor-1α accumulation via AMPK-mediated prolyl hydroxylase regulation.
    Seo K; Seo S; Ki SH; Shin SM
    Free Radic Biol Med; 2016 Dec; 101():511-523. PubMed ID: 27840318
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Dimethyl fumarate inhibits the expression and function of hypoxia-inducible factor-1α (HIF-1α).
    Zhao G; Liu Y; Fang J; Chen Y; Li H; Gao K
    Biochem Biophys Res Commun; 2014 Jun; 448(3):303-7. PubMed ID: 24569076
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Kamebakaurin inhibits the expression of hypoxia-inducible factor-1α and its target genes to confer antitumor activity.
    Wang KS; Ma J; Mi C; Li J; Lee JJ; Jin X
    Oncol Rep; 2016 Apr; 35(4):2045-52. PubMed ID: 26781327
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Magnolol suppresses hypoxia-induced angiogenesis via inhibition of HIF-1α/VEGF signaling pathway in human bladder cancer cells.
    Chen MC; Lee CF; Huang WH; Chou TC
    Biochem Pharmacol; 2013 May; 85(9):1278-87. PubMed ID: 23416116
    [TBL] [Abstract][Full Text] [Related]  

  • 19. ERRα augments HIF-1 signalling by directly interacting with HIF-1α in normoxic and hypoxic prostate cancer cells.
    Zou C; Yu S; Xu Z; Wu D; Ng CF; Yao X; Yew DT; Vanacker JM; Chan FL
    J Pathol; 2014 May; 233(1):61-73. PubMed ID: 24425001
    [TBL] [Abstract][Full Text] [Related]  

  • 20. DNA-dependent protein kinase is involved in heat shock protein-mediated accumulation of hypoxia-inducible factor-1alpha in hypoxic preconditioned HepG2 cells.
    Kang MJ; Jung SM; Kim MJ; Bae JH; Kim HB; Kim JY; Park SJ; Song HS; Kim DW; Kang CD; Kim SH
    FEBS J; 2008 Dec; 275(23):5969-81. PubMed ID: 19021771
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.