119 related articles for article (PubMed ID: 21414693)
1. A class of novel N-isoquinoline-3-carbonyl-L-amino acid benzylesters: synthesis, anti-tumor evaluation and 3D QSAR analysis.
Zheng M; Yang Y; Zhao M; Zhang X; Wu J; Chen G; Peng L; Wang Y; Peng S
Eur J Med Chem; 2011 May; 46(5):1672-81. PubMed ID: 21414693
[TBL] [Abstract][Full Text] [Related]
2. A class of novel carboline intercalators: Their synthesis, in vitro anti-proliferation, in vivo anti-tumor action, and 3D QSAR analysis.
Wu J; Li C; Zhao M; Wang W; Wang Y; Peng S
Bioorg Med Chem; 2010 Sep; 18(17):6220-9. PubMed ID: 20692841
[TBL] [Abstract][Full Text] [Related]
3. Design, synthesis, and testing of an isoquinoline-3-carboxylic-based novel anti-tumor lead.
Gao F; Liu H; Li L; Guo J; Wang Y; Zhao M; Peng S
Bioorg Med Chem Lett; 2015 Oct; 25(20):4434-6. PubMed ID: 26386603
[TBL] [Abstract][Full Text] [Related]
4. Synthesis and structure-activity relationships of a novel class of dithiocarbamic acid esters as anticancer agent.
Hou X; Ge Z; Wang T; Guo W; Wu J; Cui J; Lai C; Li R
Arch Pharm (Weinheim); 2011 May; 344(5):320-32. PubMed ID: 21509804
[TBL] [Abstract][Full Text] [Related]
5. Synthesis of 5,6-dihydropyrrolo[2,1-a]isoquinolines featuring an intramolecular radical-oxidative cyclization of polysubstituted pyrroles, and evaluation of their cytotoxic activity.
Reyes-Gutiérrez PE; Camacho JR; Ramírez-Apan MT; Osornio YM; Martínez R
Org Biomol Chem; 2010 Oct; 8(19):4374-82. PubMed ID: 20672155
[TBL] [Abstract][Full Text] [Related]
6. Discovery of 4-(benzylaminomethylene)isoquinoline-1,3-(2H,4H)-diones and 4-[(pyridylmethyl)aminomethylene]isoquinoline-1,3-(2H,4H)-diones as potent and selective inhibitors of the cyclin-dependent kinase 4.
Tsou HR; Liu X; Birnberg G; Kaplan J; Otteng M; Tran T; Kutterer K; Tang Z; Suayan R; Zask A; Ravi M; Bretz A; Grillo M; McGinnis JP; Rabindran SK; Ayral-Kaloustian S; Mansour TS
J Med Chem; 2009 Apr; 52(8):2289-310. PubMed ID: 19317452
[TBL] [Abstract][Full Text] [Related]
7. [Synthesis and structure-activity relationship of N-(2-arylethyl) isoquinoline derivatives as anti-cancer agents].
Wang YX; Zhao WL; Bi CW; Li YB; Shao RG; Song DQ
Yao Xue Xue Bao; 2012 Feb; 47(2):200-5. PubMed ID: 22512031
[TBL] [Abstract][Full Text] [Related]
8. 4-(Phenylaminomethylene)isoquinoline-1,3(2H,4H)-diones as potent and selective inhibitors of the cyclin-dependent kinase 4 (CDK4).
Tsou HR; Otteng M; Tran T; Floyd MB; Reich M; Birnberg G; Kutterer K; Ayral-Kaloustian S; Ravi M; Nilakantan R; Grillo M; McGinnis JP; Rabindran SK
J Med Chem; 2008 Jun; 51(12):3507-25. PubMed ID: 18494457
[TBL] [Abstract][Full Text] [Related]
9. Novel N-(3-carboxyl-9-benzyl-beta-carboline-1-yl)ethylamino acids: synthesis, anti-tumor evaluation, intercalating determination, 3D QSAR analysis and docking investigation.
Wu J; Zhao M; Qian K; Lee KH; Morris-Natschke S; Peng S
Eur J Med Chem; 2009 Oct; 44(10):4153-61. PubMed ID: 19535177
[TBL] [Abstract][Full Text] [Related]
10. A class of Trp-Trp-AA-OBzl: Synthesis, in vitro anti-proliferation/in vivo anti-tumor evaluation, intercalation-mechanism investigation and 3D QSAR analysis.
Zhang X; Yang Y; Zhao M; Liu L; Zheng M; Wang Y; Wu J; Peng S
Eur J Med Chem; 2011 Aug; 46(8):3410-9. PubMed ID: 21620529
[TBL] [Abstract][Full Text] [Related]
11. Development of highly potent inhibitors of Ras farnesyltransferase possessing cellular and in vivo activity.
Leftheris K; Kline T; Vite GD; Cho YH; Bhide RS; Patel DV; Patel MM; Schmidt RJ; Weller HN; Andahazy ML; Carboni JM; Gullo-Brown JL; Lee FY; Ricca C; Rose WC; Yan N; Barbacid M; Hunt JT; Meyers CA; Seizinger BR; Zahler R; Manne V
J Med Chem; 1996 Jan; 39(1):224-36. PubMed ID: 8568812
[TBL] [Abstract][Full Text] [Related]
12. 3-(4-Aroyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-propenamides as a new class of synthetic histone deacetylase inhibitors. 2. Effect of pyrrole-C2 and/or -C4 substitutions on biological activity.
Mai A; Massa S; Cerbara I; Valente S; Ragno R; Bottoni P; Scatena R; Loidl P; Brosch G
J Med Chem; 2004 Feb; 47(5):1098-109. PubMed ID: 14971890
[TBL] [Abstract][Full Text] [Related]
13. Analogues of N alpha-(4-amino-4-deoxypteroyl)-N delta-hemiphthaloyl-L-ornithine (PT523) modified in the side chain: synthesis and biological evaluation.
Rosowsky A; Vaidya CM; Bader H; Wright JE; Teicher BA
J Med Chem; 1997 Jan; 40(3):286-99. PubMed ID: 9022795
[TBL] [Abstract][Full Text] [Related]
14. Synthesis and cytotoxic activities of beta-carboline amino acid ester conjugates.
Zhao M; Bi L; Wang W; Wang C; Baudy-Floc'h M; Ju J; Peng S
Bioorg Med Chem; 2006 Oct; 14(20):6998-7010. PubMed ID: 16806943
[TBL] [Abstract][Full Text] [Related]
15. A new class of anti-thrombosis hexahydropyrazino-[1',2':1,6]pyrido-[3,4-b]-indole-1,4-dions: design, synthesis, logK determination, and QSAR analysis.
Liu J; Wu G; Cui G; Wang WX; Zhao M; Wang C; Zhang Z; Peng S
Bioorg Med Chem; 2007 Sep; 15(17):5672-93. PubMed ID: 17590343
[TBL] [Abstract][Full Text] [Related]
16. (R,R)-2,2'-[1,2-ethanediylbis[imino(1-methyl-2,1-ethanediyl)]]- bis[5-nitro-1H-benz[de]isoquinoline-1,3-(2H)-dione] dimethanesulfonate (DMP 840), a novel bis-naphthalimide with potent nonselective tumoricidal activity in vitro.
Kirshenbaum MR; Chen SF; Behrens CH; Papp LM; Stafford MM; Sun JH; Behrens DL; Fredericks JR; Polkus ST; Sipple P
Cancer Res; 1994 Apr; 54(8):2199-206. PubMed ID: 8174127
[TBL] [Abstract][Full Text] [Related]
17. Synthesis, pharmacological activity and comparative QSAR modeling of 1,5-N,N'-substituted-2-(substituted naphthalenesulphonyl) glutamamides as possible anticancer agents.
Halder AK; Adhikary N; Maity MK; Jha T
Eur J Med Chem; 2010 May; 45(5):1760-71. PubMed ID: 20133022
[TBL] [Abstract][Full Text] [Related]
18. Thieno[3,2-c]pyrazoles: a novel class of Aurora inhibitors with favorable antitumor activity.
Bindi S; Fancelli D; Alli C; Berta D; Bertrand JA; Cameron AD; Cappella P; Carpinelli P; Cervi G; Croci V; D'Anello M; Forte B; Giorgini ML; Marsiglio A; Moll J; Pesenti E; Pittalà V; Pulici M; Riccardi-Sirtori F; Roletto F; Soncini C; Storici P; Varasi M; Volpi D; Zugnoni P; Vianello P
Bioorg Med Chem; 2010 Oct; 18(19):7113-20. PubMed ID: 20817473
[TBL] [Abstract][Full Text] [Related]
19. Isolation, synthesis, and anti-tumor activities of a novel class of podocarpic diterpenes.
Xiong Y; Wang K; Pan Y; Sun H; Tu J
Bioorg Med Chem Lett; 2006 Feb; 16(4):786-9. PubMed ID: 16309905
[TBL] [Abstract][Full Text] [Related]
20. Quinolino-benzo-[5, 6]-dihydroisoquindolium compounds derived from berberine: a new class of highly selective ligands for G-quadruplex DNA in c-myc oncogene.
Ma Y; Ou TM; Tan JH; Hou JQ; Huang SL; Gu LQ; Huang ZS
Eur J Med Chem; 2011 May; 46(5):1906-13. PubMed ID: 21392861
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
