181 related articles for article (PubMed ID: 21416055)
1. Targeting transcription factor Stat5a/b as a therapeutic strategy for prostate cancer.
Liao Z; Nevalainen MT
Am J Transl Res; 2011 Feb; 3(2):133-8. PubMed ID: 21416055
[TBL] [Abstract][Full Text] [Related]
2. Pharmacologic inhibition of Jak2-Stat5 signaling By Jak2 inhibitor AZD1480 potently suppresses growth of both primary and castrate-resistant prostate cancer.
Gu L; Liao Z; Hoang DT; Dagvadorj A; Gupta S; Blackmon S; Ellsworth E; Talati P; Leiby B; Zinda M; Lallas CD; Trabulsi EJ; McCue P; Gomella L; Huszar D; Nevalainen MT
Clin Cancer Res; 2013 Oct; 19(20):5658-74. PubMed ID: 23942095
[TBL] [Abstract][Full Text] [Related]
3. Transcription factor signal transducer and activator of transcription 5 promotes growth of human prostate cancer cells in vivo.
Dagvadorj A; Kirken RA; Leiby B; Karras J; Nevalainen MT
Clin Cancer Res; 2008 Mar; 14(5):1317-24. PubMed ID: 18316550
[TBL] [Abstract][Full Text] [Related]
4. Signal transducer and activator of transcription 5A/B in prostate and breast cancers.
Tan SH; Nevalainen MT
Endocr Relat Cancer; 2008 Jun; 15(2):367-90. PubMed ID: 18508994
[TBL] [Abstract][Full Text] [Related]
5. Transcription factor Stat5 synergizes with androgen receptor in prostate cancer cells.
Tan SH; Dagvadorj A; Shen F; Gu L; Liao Z; Abdulghani J; Zhang Y; Gelmann EP; Zellweger T; Culig Z; Visakorpi T; Bubendorf L; Kirken RA; Karras J; Nevalainen MT
Cancer Res; 2008 Jan; 68(1):236-48. PubMed ID: 18172316
[TBL] [Abstract][Full Text] [Related]
6. Jak2-Stat5a/b Signaling Induces Epithelial-to-Mesenchymal Transition and Stem-Like Cell Properties in Prostate Cancer.
Talati PG; Gu L; Ellsworth EM; Girondo MA; Trerotola M; Hoang DT; Leiby B; Dagvadorj A; McCue PA; Lallas CD; Trabulsi EJ; Gomella L; Aplin AE; Languino L; Fatatis A; Rui H; Nevalainen MT
Am J Pathol; 2015 Sep; 185(9):2505-22. PubMed ID: 26362718
[TBL] [Abstract][Full Text] [Related]
7. Signal transducer and activator of transcription 5a/b: biomarker and therapeutic target in prostate and breast cancer.
Koptyra M; Gupta S; Talati P; Nevalainen MT
Int J Biochem Cell Biol; 2011 Oct; 43(10):1417-21. PubMed ID: 21704724
[TBL] [Abstract][Full Text] [Related]
8. Prolactin receptor targeting in breast and prostate cancers: New insights into an old challenge.
Goffin V
Pharmacol Ther; 2017 Nov; 179():111-126. PubMed ID: 28549597
[TBL] [Abstract][Full Text] [Related]
9. Autocrine prolactin promotes prostate cancer cell growth via Janus kinase-2-signal transducer and activator of transcription-5a/b signaling pathway.
Dagvadorj A; Collins S; Jomain JB; Abdulghani J; Karras J; Zellweger T; Li H; Nurmi M; Alanen K; Mirtti T; Visakorpi T; Bubendorf L; Goffin V; Nevalainen MT
Endocrinology; 2007 Jul; 148(7):3089-101. PubMed ID: 17412813
[TBL] [Abstract][Full Text] [Related]
10. N-terminal truncation of Stat5a/b circumvents PIAS3-mediated transcriptional inhibition of Stat5 in prostate cancer cells.
Dagvadorj A; Tan SH; Liao Z; Xie J; Nurmi M; Alanen K; Rui H; Mirtti T; Nevalainen MT
Int J Biochem Cell Biol; 2010 Dec; 42(12):2037-46. PubMed ID: 20854925
[TBL] [Abstract][Full Text] [Related]
11. Inhibition of Stat5a/b Enhances Proteasomal Degradation of Androgen Receptor Liganded by Antiandrogens in Prostate Cancer.
Hoang DT; Gu L; Liao Z; Shen F; Talati PG; Koptyra M; Tan SH; Ellsworth E; Gupta S; Montie H; Dagvadorj A; Savolainen S; Leiby B; Mirtti T; Merry DE; Nevalainen MT
Mol Cancer Ther; 2015 Mar; 14(3):713-26. PubMed ID: 25552366
[TBL] [Abstract][Full Text] [Related]
12. STAT5a/b Deficiency Delays, but does not Prevent, Prolactin-Driven Prostate Tumorigenesis in Mice.
Boutillon F; Pigat N; Sala LS; Reyes-Gomez E; Moriggl R; Guidotti JE; Goffin V
Cancers (Basel); 2019 Jul; 11(7):. PubMed ID: 31269779
[TBL] [Abstract][Full Text] [Related]
13. STAT5A/B Blockade Sensitizes Prostate Cancer to Radiation through Inhibition of RAD51 and DNA Repair.
Maranto C; Udhane V; Hoang DT; Gu L; Alexeev V; Malas K; Cardenas K; Brody JR; Rodeck U; Bergom C; Iczkowski KA; Jacobsohn K; See W; Schmitt SM; Nevalainen MT
Clin Cancer Res; 2018 Apr; 24(8):1917-1931. PubMed ID: 29483142
[No Abstract] [Full Text] [Related]
14. STAT5A/B gene locus undergoes amplification during human prostate cancer progression.
Haddad BR; Gu L; Mirtti T; Dagvadorj A; Vogiatzi P; Hoang DT; Bajaj R; Leiby B; Ellsworth E; Blackmon S; Ruiz C; Curtis M; Fortina P; Ertel A; Liu C; Rui H; Visakorpi T; Bubendorf L; Lallas CD; Trabulsi EJ; McCue P; Gomella L; Nevalainen MT
Am J Pathol; 2013 Jun; 182(6):2264-75. PubMed ID: 23660011
[TBL] [Abstract][Full Text] [Related]
15. Prolactin inhibits BCL6 expression in breast cancer through a Stat5a-dependent mechanism.
Tran TH; Utama FE; Lin J; Yang N; Sjolund AB; Ryder A; Johnson KJ; Neilson LM; Liu C; Brill KL; Rosenberg AL; Witkiewicz AK; Rui H
Cancer Res; 2010 Feb; 70(4):1711-21. PubMed ID: 20124477
[TBL] [Abstract][Full Text] [Related]
16. Activating mutation (V617F) in the tyrosine kinase JAK2 is absent in locally-confined or castration-resistant prostate cancer.
Gu L; Zhu XH; Visakorpi T; Alanen K; Mirtti T; Edmonston TB; Nevalainen MT
Anal Cell Pathol (Amst); 2010; 33(2):55-9. PubMed ID: 20966544
[TBL] [Abstract][Full Text] [Related]
17. Structure-Based Screen Identifies a Potent Small Molecule Inhibitor of Stat5a/b with Therapeutic Potential for Prostate Cancer and Chronic Myeloid Leukemia.
Liao Z; Gu L; Vergalli J; Mariani SA; De Dominici M; Lokareddy RK; Dagvadorj A; Purushottamachar P; McCue PA; Trabulsi E; Lallas CD; Gupta S; Ellsworth E; Blackmon S; Ertel A; Fortina P; Leiby B; Xia G; Rui H; Hoang DT; Gomella LG; Cingolani G; Njar V; Pattabiraman N; Calabretta B; Nevalainen MT
Mol Cancer Ther; 2015 Aug; 14(8):1777-93. PubMed ID: 26026053
[TBL] [Abstract][Full Text] [Related]
18. Transcription factor Stat3 stimulates metastatic behavior of human prostate cancer cells in vivo, whereas Stat5b has a preferential role in the promotion of prostate cancer cell viability and tumor growth.
Gu L; Dagvadorj A; Lutz J; Leiby B; Bonuccelli G; Lisanti MP; Addya S; Fortina P; Dasgupta A; Hyslop T; Bubendorf L; Nevalainen MT
Am J Pathol; 2010 Apr; 176(4):1959-72. PubMed ID: 20167868
[TBL] [Abstract][Full Text] [Related]
19. Coactivation of janus tyrosine kinase (Jak)1 positively modulates prolactin-Jak2 signaling in breast cancer: recruitment of ERK and signal transducer and activator of transcription (Stat)3 and enhancement of Akt and Stat5a/b pathways.
Neilson LM; Zhu J; Xie J; Malabarba MG; Sakamoto K; Wagner KU; Kirken RA; Rui H
Mol Endocrinol; 2007 Sep; 21(9):2218-32. PubMed ID: 17550976
[TBL] [Abstract][Full Text] [Related]
20. Nuclear Stat5a/b predicts early recurrence and prostate cancer-specific death in patients treated by radical prostatectomy.
Mirtti T; Leiby BE; Abdulghani J; Aaltonen E; Pavela M; Mamtani A; Alanen K; Egevad L; Granfors T; Josefsson A; Stattin P; Bergh A; Nevalainen MT
Hum Pathol; 2013 Mar; 44(3):310-9. PubMed ID: 23026195
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
