These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
3. On the use of the antibiotic chloramphenicol to target polypeptide chain mimics to the ribosomal exit tunnel. Mamos P; Krokidis MG; Papadas A; Karahalios P; Starosta AL; Wilson DN; Kalpaxis DL; Dinos GP Biochimie; 2013 Sep; 95(9):1765-72. PubMed ID: 23770443 [TBL] [Abstract][Full Text] [Related]
4. Statics of the ribosomal exit tunnel: implications for cotranslational peptide folding, elongation regulation, and antibiotics binding. Fulle S; Gohlke H J Mol Biol; 2009 Mar; 387(2):502-17. PubMed ID: 19356596 [TBL] [Abstract][Full Text] [Related]
5. Nascent peptide in the ribosome exit tunnel affects functional properties of the A-site of the peptidyl transferase center. Ramu H; Vázquez-Laslop N; Klepacki D; Dai Q; Piccirilli J; Micura R; Mankin AS Mol Cell; 2011 Feb; 41(3):321-30. PubMed ID: 21292164 [TBL] [Abstract][Full Text] [Related]
6. Nascent polypeptide chains emerge from the exit domain of the large ribosomal subunit: immune mapping of the nascent chain. Bernabeu C; Lake JA Proc Natl Acad Sci U S A; 1982 May; 79(10):3111-5. PubMed ID: 6808502 [TBL] [Abstract][Full Text] [Related]
7. Cotranslational folding--omnia mea mecum porto? Kramer G; Ramachandiran V; Hardesty B Int J Biochem Cell Biol; 2001 Jun; 33(6):541-53. PubMed ID: 11378437 [TBL] [Abstract][Full Text] [Related]
8. Ribosomal crystallography: initiation, peptide bond formation, and amino acid polymerization are hampered by antibiotics. Yonath A; Bashan A Annu Rev Microbiol; 2004; 58():233-51. PubMed ID: 15487937 [TBL] [Abstract][Full Text] [Related]
9. Regional discrimination and propagation of local rearrangements along the ribosomal exit tunnel. Lu J; Deutsch C J Mol Biol; 2014 Dec; 426(24):4061-4073. PubMed ID: 25308341 [TBL] [Abstract][Full Text] [Related]
10. Macrolide-peptide conjugates as probes of the path of travel of the nascent peptides through the ribosome. Washington AZ; Benicewicz DB; Canzoneri JC; Fagan CE; Mwakwari SC; Maehigashi T; Dunham CM; Oyelere AK ACS Chem Biol; 2014 Nov; 9(11):2621-31. PubMed ID: 25198768 [TBL] [Abstract][Full Text] [Related]
11. Path of nascent polypeptide in exit tunnel revealed by molecular dynamics simulation of ribosome. Ishida H; Hayward S Biophys J; 2008 Dec; 95(12):5962-73. PubMed ID: 18936244 [TBL] [Abstract][Full Text] [Related]
12. Mechanistic Insight into the Reactivation of BCAII Enzyme from Denatured and Molten Globule States by Eukaryotic Ribosomes and Domain V rRNAs. Chakraborty B; Bhakta S; Sengupta J PLoS One; 2016; 11(4):e0153928. PubMed ID: 27099964 [TBL] [Abstract][Full Text] [Related]
13. SecM-stalled ribosomes adopt an altered geometry at the peptidyl transferase center. Bhushan S; Hoffmann T; Seidelt B; Frauenfeld J; Mielke T; Berninghausen O; Wilson DN; Beckmann R PLoS Biol; 2011 Jan; 9(1):e1000581. PubMed ID: 21267063 [TBL] [Abstract][Full Text] [Related]
14. Ribosomal crystallography: peptide bond formation and its inhibition. Bashan A; Zarivach R; Schluenzen F; Agmon I; Harms J; Auerbach T; Baram D; Berisio R; Bartels H; Hansen HA; Fucini P; Wilson D; Peretz M; Kessler M; Yonath A Biopolymers; 2003 Sep; 70(1):19-41. PubMed ID: 12925991 [TBL] [Abstract][Full Text] [Related]
15. Ribosome protection by antibiotic resistance ATP-binding cassette protein. Su W; Kumar V; Ding Y; Ero R; Serra A; Lee BST; Wong ASW; Shi J; Sze SK; Yang L; Gao YG Proc Natl Acad Sci U S A; 2018 May; 115(20):5157-5162. PubMed ID: 29712846 [TBL] [Abstract][Full Text] [Related]
16. alpha-Helical nascent polypeptide chains visualized within distinct regions of the ribosomal exit tunnel. Bhushan S; Gartmann M; Halic M; Armache JP; Jarasch A; Mielke T; Berninghausen O; Wilson DN; Beckmann R Nat Struct Mol Biol; 2010 Mar; 17(3):313-7. PubMed ID: 20139981 [TBL] [Abstract][Full Text] [Related]
17. Peptidyl transferase center decompaction and structural constraints during early protein elongation on the ribosome. Jia B; Wang T; Lehmann J Sci Rep; 2021 Dec; 11(1):24061. PubMed ID: 34911999 [TBL] [Abstract][Full Text] [Related]
18. Interaction of nascent chains with the ribosomal tunnel proteins Rpl4, Rpl17, and Rpl39 of Saccharomyces cerevisiae. Zhang Y; Wölfle T; Rospert S J Biol Chem; 2013 Nov; 288(47):33697-33707. PubMed ID: 24072706 [TBL] [Abstract][Full Text] [Related]