BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

210 related articles for article (PubMed ID: 21419339)

  • 1. Inhibition of protein phosphatase 2A activity by PI3Kγ regulates β-adrenergic receptor function.
    Vasudevan NT; Mohan ML; Gupta MK; Hussain AK; Naga Prasad SV
    Mol Cell; 2011 Mar; 41(6):636-48. PubMed ID: 21419339
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Hypoxia Sensing of β-Adrenergic Receptor Is Regulated by Endosomal PI3Kγ.
    Sun Y; Stenson K; Mohan ML; Gupta MK; Wanner N; Asosingh K; Erzurum S; Naga Prasad SV
    Circ Res; 2023 Mar; 132(6):690-703. PubMed ID: 36779349
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Phosphoinositide 3-kinase γ inhibits cardiac GSK-3 independently of Akt.
    Mohan ML; Jha BK; Gupta MK; Vasudevan NT; Martelli EE; Mosinski JD; Naga Prasad SV
    Sci Signal; 2013 Jan; 6(259):ra4. PubMed ID: 23354687
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Defective Resensitization in Human Airway Smooth Muscle Cells Evokes β-Adrenergic Receptor Dysfunction in Severe Asthma.
    Gupta MK; Asosingh K; Aronica M; Comhair S; Cao G; Erzurum S; Panettieri RA; Naga Prasad SV
    PLoS One; 2015; 10(5):e0125803. PubMed ID: 26023787
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Phosphoproteome and drug-response effects mediated by the three protein phosphatase 2A inhibitor proteins CIP2A, SET, and PME-1.
    Kauko O; Imanishi SY; Kulesskiy E; Yetukuri L; Laajala TD; Sharma M; Pavic K; Aakula A; Rupp C; Jumppanen M; Haapaniemi P; Ruan L; Yadav B; Suni V; Varila T; Corthals GL; Reimand J; Wennerberg K; Aittokallio T; Westermarck J
    J Biol Chem; 2020 Mar; 295(13):4194-4211. PubMed ID: 32071079
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification of upregulated phosphoinositide 3-kinase γ as a target to suppress breast cancer cell migration and invasion.
    Xie Y; Abel PW; Kirui JK; Deng C; Sharma P; Wolff DW; Toews ML; Tu Y
    Biochem Pharmacol; 2013 May; 85(10):1454-62. PubMed ID: 23500535
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Sphingosine analogue drug FTY720 targets I2PP2A/SET and mediates lung tumour suppression via activation of PP2A-RIPK1-dependent necroptosis.
    Saddoughi SA; Gencer S; Peterson YK; Ward KE; Mukhopadhyay A; Oaks J; Bielawski J; Szulc ZM; Thomas RJ; Selvam SP; Senkal CE; Garrett-Mayer E; De Palma RM; Fedarovich D; Liu A; Habib AA; Stahelin RV; Perrotti D; Ogretmen B
    EMBO Mol Med; 2013 Jan; 5(1):105-21. PubMed ID: 23180565
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Noncanonical regulation of insulin-mediated ERK activation by phosphoinositide 3-kinase γ.
    Mohan ML; Chatterjee A; Ganapathy S; Mukherjee S; Srikanthan S; Jolly GP; Anand RS; Naga Prasad SV
    Mol Biol Cell; 2017 Nov; 28(22):3112-3122. PubMed ID: 28877982
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Targeted inhibition of beta-adrenergic receptor kinase-1-associated phosphoinositide-3 kinase activity preserves beta-adrenergic receptor signaling and prolongs survival in heart failure induced by calsequestrin overexpression.
    Perrino C; Naga Prasad SV; Patel M; Wolf MJ; Rockman HA
    J Am Coll Cardiol; 2005 Jun; 45(11):1862-70. PubMed ID: 15936620
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Dynamic regulation of phosphoinositide 3-kinase-gamma activity and beta-adrenergic receptor trafficking in end-stage human heart failure.
    Perrino C; Schroder JN; Lima B; Villamizar N; Nienaber JJ; Milano CA; Naga Prasad SV
    Circulation; 2007 Nov; 116(22):2571-9. PubMed ID: 17998459
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Activated Protein Phosphatase 2A Disrupts Nutrient Sensing Balance Between Mechanistic Target of Rapamycin Complex 1 and Adenosine Monophosphate-Activated Protein Kinase, Causing Sarcopenia in Alcohol-Associated Liver Disease.
    Davuluri G; Welch N; Sekar J; Gangadhariah M; Alsabbagh Alchirazi K; Mohan ML; Kumar A; Kant S; Thapaliya S; Stine M; McMullen MR; McCullough RL; Stark GR; Nagy LE; Naga Prasad SV; Dasarathy S
    Hepatology; 2021 May; 73(5):1892-1908. PubMed ID: 32799332
    [TBL] [Abstract][Full Text] [Related]  

  • 12. PI3Kγ (Phosphoinositide 3-Kinase γ) Regulates Vascular Smooth Muscle Cell Phenotypic Modulation and Neointimal Formation Through CREB (Cyclic AMP-Response Element Binding Protein)/YAP (Yes-Associated Protein) Signaling.
    Yu Q; Li W; Jin R; Yu S; Xie D; Zheng X; Zhong W; Cheng X; Hu S; Li M; Zheng Q; Li G; Song Z
    Arterioscler Thromb Vasc Biol; 2019 Mar; 39(3):e91-e105. PubMed ID: 30651001
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Isoliensinine induces dephosphorylation of NF-kB p65 subunit at Ser536 via a PP2A-dependent mechanism in hepatocellular carcinoma cells: roles of impairing PP2A/I2PP2A interaction.
    Shu G; Zhang L; Jiang S; Cheng Z; Wang G; Huang X; Yang X
    Oncotarget; 2016 Jun; 7(26):40285-40296. PubMed ID: 27244888
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Direct interaction between the inhibitor 2 and ceramide via sphingolipid-protein binding is involved in the regulation of protein phosphatase 2A activity and signaling.
    Mukhopadhyay A; Saddoughi SA; Song P; Sultan I; Ponnusamy S; Senkal CE; Snook CF; Arnold HK; Sears RC; Hannun YA; Ogretmen B
    FASEB J; 2009 Mar; 23(3):751-63. PubMed ID: 19028839
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Targeting inhibitors of the tumor suppressor PP2A for the treatment of pancreatic cancer.
    Farrell AS; Allen-Petersen B; Daniel CJ; Wang X; Wang Z; Rodriguez S; Impey S; Oddo J; Vitek MP; Lopez C; Christensen DJ; Sheppard B; Sears RC
    Mol Cancer Res; 2014 Jun; 12(6):924-39. PubMed ID: 24667985
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Targeting inhibitor 2 of protein phosphatase 2A as a therapeutic strategy for prostate cancer treatment.
    Mukhopadhyay A; Tabanor K; Chaguturu R; Aldrich JV
    Cancer Biol Ther; 2013 Oct; 14(10):962-72. PubMed ID: 24025258
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Phosphoinositide 3-kinase γ protects against catecholamine-induced ventricular arrhythmia through protein kinase A-mediated regulation of distinct phosphodiesterases.
    Ghigo A; Perino A; Mehel H; Zahradníková A; Morello F; Leroy J; Nikolaev VO; Damilano F; Cimino J; De Luca E; Richter W; Westenbroek R; Catterall WA; Zhang J; Yan C; Conti M; Gomez AM; Vandecasteele G; Hirsch E; Fischmeister R
    Circulation; 2012 Oct; 126(17):2073-83. PubMed ID: 23008439
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Regulation of β-adrenergic receptor function: an emphasis on receptor resensitization.
    Vasudevan NT; Mohan ML; Goswami SK; Naga Prasad SV
    Cell Cycle; 2011 Nov; 10(21):3684-91. PubMed ID: 22041711
    [TBL] [Abstract][Full Text] [Related]  

  • 19. PKCβ phosphorylates PI3Kγ to activate it and release it from GPCR control.
    Walser R; Burke JE; Gogvadze E; Bohnacker T; Zhang X; Hess D; Küenzi P; Leitges M; Hirsch E; Williams RL; Laffargue M; Wymann MP
    PLoS Biol; 2013; 11(6):e1001587. PubMed ID: 23824069
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Protein phosphatase 2A negatively regulates insulin's metabolic signaling pathway by inhibiting Akt (protein kinase B) activity in 3T3-L1 adipocytes.
    Ugi S; Imamura T; Maegawa H; Egawa K; Yoshizaki T; Shi K; Obata T; Ebina Y; Kashiwagi A; Olefsky JM
    Mol Cell Biol; 2004 Oct; 24(19):8778-89. PubMed ID: 15367694
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.