BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

185 related articles for article (PubMed ID: 21419846)

  • 1. The mechanism of cell membrane ruffling relies on a phospholipase D2 (PLD2), Grb2 and Rac2 association.
    Mahankali M; Peng HJ; Cox D; Gomez-Cambronero J
    Cell Signal; 2011 Aug; 23(8):1291-8. PubMed ID: 21419846
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A novel phospholipase D2-Grb2-WASp heterotrimer regulates leukocyte phagocytosis in a two-step mechanism.
    Kantonen S; Hatton N; Mahankali M; Henkels KM; Park H; Cox D; Gomez-Cambronero J
    Mol Cell Biol; 2011 Nov; 31(22):4524-37. PubMed ID: 21930784
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The exquisite regulation of PLD2 by a wealth of interacting proteins: S6K, Grb2, Sos, WASp and Rac2 (and a surprise discovery: PLD2 is a GEF).
    Gomez-Cambronero J
    Cell Signal; 2011 Dec; 23(12):1885-95. PubMed ID: 21740967
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The molecular basis of phospholipase D2-induced chemotaxis: elucidation of differential pathways in macrophages and fibroblasts.
    Knapek K; Frondorf K; Post J; Short S; Cox D; Gomez-Cambronero J
    Mol Cell Biol; 2010 Sep; 30(18):4492-506. PubMed ID: 20647543
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Evidence for two CRIB domains in phospholipase D2 (PLD2) that the enzyme uses to specifically bind to the small GTPase Rac2.
    Peng HJ; Henkels KM; Mahankali M; Dinauer MC; Gomez-Cambronero J
    J Biol Chem; 2011 May; 286(18):16308-20. PubMed ID: 21378159
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The Grb2/PLD2 interaction is essential for lipase activity, intracellular localization and signaling in response to EGF.
    Di Fulvio M; Frondorf K; Henkels KM; Lehman N; Gomez-Cambronero J
    J Mol Biol; 2007 Mar; 367(3):814-24. PubMed ID: 17276458
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Phospholipase D2 (PLD2) is a guanine nucleotide exchange factor (GEF) for the GTPase Rac2.
    Mahankali M; Peng HJ; Henkels KM; Dinauer MC; Gomez-Cambronero J
    Proc Natl Acad Sci U S A; 2011 Dec; 108(49):19617-22. PubMed ID: 22106281
    [TBL] [Abstract][Full Text] [Related]  

  • 8. PLD Protein-Protein Interactions With Signaling Molecules and Modulation by PA.
    Gomez-Cambronero J; Morris AJ; Henkels KM
    Methods Enzymol; 2017; 583():327-357. PubMed ID: 28063497
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The dual effect of Rac2 on phospholipase D2 regulation that explains both the onset and termination of chemotaxis.
    Peng HJ; Henkels KM; Mahankali M; Marchal C; Bubulya P; Dinauer MC; Gomez-Cambronero J
    Mol Cell Biol; 2011 Jun; 31(11):2227-40. PubMed ID: 21444720
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The elucidation of novel SH2 binding sites on PLD2.
    Di Fulvio M; Lehman N; Lin X; Lopez I; Gomez-Cambronero J
    Oncogene; 2006 May; 25(21):3032-40. PubMed ID: 16407827
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification of the catalytic site of phospholipase D2 (PLD2) newly described guanine nucleotide exchange factor activity.
    Mahankali M; Henkels KM; Alter G; Gomez-Cambronero J
    J Biol Chem; 2012 Nov; 287(49):41417-31. PubMed ID: 23035122
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Continual production of phosphatidic acid by phospholipase D is essential for antigen-stimulated membrane ruffling in cultured mast cells.
    O'Luanaigh N; Pardo R; Fensome A; Allen-Baume V; Jones D; Holt MR; Cockcroft S
    Mol Biol Cell; 2002 Oct; 13(10):3730-46. PubMed ID: 12388770
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Endogenous phospholipase D2 localizes to the plasma membrane of RBL-2H3 mast cells and can be distinguished from ADP ribosylation factor-stimulated phospholipase D1 activity by its specific sensitivity to oleic acid.
    Sarri E; Pardo R; Fensome-Green A; Cockcroft S
    Biochem J; 2003 Jan; 369(Pt 2):319-29. PubMed ID: 12374567
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Phospholipase D in cell signaling: from a myriad of cell functions to cancer growth and metastasis.
    Gomez-Cambronero J
    J Biol Chem; 2014 Aug; 289(33):22557-22566. PubMed ID: 24990944
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mechanism of enzymatic reaction and protein-protein interactions of PLD from a 3D structural model.
    Mahankali M; Alter G; Gomez-Cambronero J
    Cell Signal; 2015 Jan; 27(1):69-81. PubMed ID: 25308783
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Membrane targeting of WAVE2 is not sufficient for WAVE2-dependent actin polymerization: a role for IRSp53 in mediating the interaction between Rac and WAVE2.
    Abou-Kheir W; Isaac B; Yamaguchi H; Cox D
    J Cell Sci; 2008 Feb; 121(Pt 3):379-90. PubMed ID: 18198193
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A GEF-to-phospholipase molecular switch caused by phosphatidic acid, Rac and JAK tyrosine kinase that explains leukocyte cell migration.
    Mahankali M; Henkels KM; Gomez-Cambronero J
    J Cell Sci; 2013 Mar; 126(Pt 6):1416-28. PubMed ID: 23378025
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The uncovering of a novel regulatory mechanism for PLD2: formation of a ternary complex with protein tyrosine phosphatase PTP1B and growth factor receptor-bound protein GRB2.
    Horn J; Lopez I; Miller MW; Gomez-Cambronero J
    Biochem Biophys Res Commun; 2005 Jun; 332(1):58-67. PubMed ID: 15896299
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cloning of PLD2 from baculovirus for studies in inflammatory responses.
    Gomez-Cambronero J; Henkels KM
    Methods Mol Biol; 2012; 861():201-25. PubMed ID: 22426721
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Rac2D57N, a dominant inhibitory Rac2 mutant that inhibits p38 kinase signaling and prevents surface ruffling in bone-marrow-derived macrophages.
    Abell AN; DeCathelineau AM; Weed SA; Ambruso DR; Riches DW; Johnson GL
    J Cell Sci; 2004 Jan; 117(Pt 2):243-55. PubMed ID: 14676277
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.