BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

168 related articles for article (PubMed ID: 21422114)

  • 1. CDKN1B, encoding the cyclin-dependent kinase inhibitor 1B (p27), is located in the minimally deleted region of 12p abnormalities in myeloid malignancies and its low expression is a favorable prognostic marker in acute myeloid leukemia.
    Haferlach C; Bacher U; Kohlmann A; Schindela S; Alpermann T; Kern W; Schnittger S; Haferlach T
    Haematologica; 2011 Jun; 96(6):829-36. PubMed ID: 21422114
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Haploinsufficiency of ETV6 and CDKN1B in patients with acute myeloid leukemia and complex karyotype.
    Feurstein S; Rücker FG; Bullinger L; Hofmann W; Manukjan G; Göhring G; Lehmann U; Heuser M; Ganser A; Döhner K; Schlegelberger B; Steinemann D
    BMC Genomics; 2014 Sep; 15(1):784. PubMed ID: 25213837
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A physical, transcript, and deletion map of chromosome region 12p12.3 flanked by ETV6 and CDKN1B: hypermethylation of the LRP6 CpG island in two leukemia patients with hemizygous del(12p).
    Baens M; Wlodarska I; Corveleyn A; Hoornaert I; Hagemeijer A; Marynen P
    Genomics; 1999 Feb; 56(1):40-50. PubMed ID: 10036184
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Deletions of CDKN1B and ETV6 in acute myeloid leukemia and myelodysplastic syndromes without cytogenetic evidence of 12p abnormalities.
    Andreasson P; Johansson B; Arheden K; Billström R; Mitelman F; Höglund M
    Genes Chromosomes Cancer; 1997 Jun; 19(2):77-83. PubMed ID: 9171997
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Fluorescence in situ hybridization analyses of hematologic malignancies reveal frequent cytogenetically unrecognized 12p rearrangements.
    Andreasson P; Johansson B; Billström R; Garwicz S; Mitelman F; Höglund M
    Leukemia; 1998 Mar; 12(3):390-400. PubMed ID: 9529134
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Gene expression of BAALC, CDKN1B, ERG, and MN1 adds independent prognostic information to cytogenetics and molecular mutations in adult acute myeloid leukemia.
    Haferlach C; Kern W; Schindela S; Kohlmann A; Alpermann T; Schnittger S; Haferlach T
    Genes Chromosomes Cancer; 2012 Mar; 51(3):257-65. PubMed ID: 22072540
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Abnormalities of the der(12)t(12;21) in ETV6-RUNX1 acute lymphoblastic leukemia.
    Al-Shehhi H; Konn ZJ; Schwab CJ; Erhorn A; Barber KE; Wright SL; Gabriel AS; Harrison CJ; Moorman AV
    Genes Chromosomes Cancer; 2013 Feb; 52(2):202-13. PubMed ID: 23077088
    [TBL] [Abstract][Full Text] [Related]  

  • 8. ETV6 rearrangements are recurrent in myeloid malignancies and are frequently associated with other genetic events.
    Haferlach C; Bacher U; Schnittger S; Alpermann T; Zenger M; Kern W; Haferlach T
    Genes Chromosomes Cancer; 2012 Apr; 51(4):328-37. PubMed ID: 22162288
    [TBL] [Abstract][Full Text] [Related]  

  • 9. TEL and KIP1 define the smallest region of deletions on 12p13 in hematopoietic malignancies.
    Sato Y; Suto Y; Pietenpol J; Golub TR; Gilliland DG; Davis EM; Le Beau MM; Roberts JM; Vogelstein B; Rowley JD
    Blood; 1995 Aug; 86(4):1525-33. PubMed ID: 7632960
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The ETV6, CDKN1B and D12S178 loci are involved in a segment commonly deleted in various 12p aberration in different hematological malignancies.
    Wlodarska I; Marynen P; La Starza R; Mecucci C; Van den Berghe H
    Cytogenet Cell Genet; 1996; 72(2-3):229-35. PubMed ID: 8978784
    [TBL] [Abstract][Full Text] [Related]  

  • 11. ETV6 mutations and loss in AML-M0.
    Silva FP; Morolli B; Storlazzi CT; Zagaria A; Impera L; Klein B; Vrieling H; Kluin-Nelemans HC; Giphart-Gassler M
    Leukemia; 2008 Aug; 22(8):1639-43. PubMed ID: 18305557
    [No Abstract]   [Full Text] [Related]  

  • 12. Chromosome microarray characterisation of chromosome arm 12p loss associated with complex molecular karyotype and recurrent adverse cytogenetic markers in multiple myeloma.
    Hung D; Lenton D; Eslick R; Blennerhassett R; Joshi M; McCaughan G; Day S; Wright D
    Genes Chromosomes Cancer; 2021 Oct; 60(10):668-677. PubMed ID: 34041820
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Two cases of myeloid disorders and a t(8;12) (q12;p13).
    Hernández JM; González MB; García JL; Ferro MT; Gutiérrez NC; Marynen P; San Miguel JF
    Haematologica; 2000 Jan; 85(1):31-4. PubMed ID: 10629588
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A complex rearrangement involving cryptic deletion of ETV6 and CDKN1B genes in a case of childhood acute lymphoblastic leukemia.
    Krstic AD; Impera L; Guc-Scekic M; Lakic N; Djokic D; Slavkovic B; Storlazzi CT
    Cancer Genet Cytogenet; 2009 Dec; 195(2):125-31. PubMed ID: 19963112
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Genomic deletion of chromosome 12p is an independent prognostic marker in prostate cancer.
    Kluth M; Ahrary R; Hube-Magg C; Ahmed M; Volta H; Schwemin C; Steurer S; Wittmer C; Wilczak W; Burandt E; Krech T; Adam M; Michl U; Heinzer H; Salomon G; Graefen M; Koop C; Minner S; Simon R; Sauter G; Schlomm T
    Oncotarget; 2015 Sep; 6(29):27966-79. PubMed ID: 26293672
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Abnormalities of the ETV6 gene occur in the majority of patients with aberrations of the short arm of chromosome 12: a combined PCR and Southern blotting analysis.
    O'Connor HE; Butler TA; Clark R; Swanton S; Harrison CJ; Secker-Walker LM; Foroni L
    Leukemia; 1998 Jul; 12(7):1099-106. PubMed ID: 9665196
    [TBL] [Abstract][Full Text] [Related]  

  • 17. ETV6 deletion is a common additional abnormality in patients with myelodysplastic syndromes or acute myeloid leukemia and monosomy 7.
    Wall M; Rayeroux KC; MacKinnon RN; Zordan A; Campbell LJ
    Haematologica; 2012 Dec; 97(12):1933-6. PubMed ID: 22875624
    [No Abstract]   [Full Text] [Related]  

  • 18. High IL2RA mRNA expression is an independent adverse prognostic biomarker in core binding factor and intermediate-risk acute myeloid leukemia.
    Du W; He J; Zhou W; Shu S; Li J; Liu W; Deng Y; Lu C; Lin S; Ma Y; He Y; Zheng J; Zhu J; Bai L; Li X; Yao J; Hu D; Gu S; Li H; Guo A; Huang S; Feng X; Hu D
    J Transl Med; 2019 Jun; 17(1):191. PubMed ID: 31171000
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Interaction between 12p chromosomal abnormalities and Lnc-HOTAIR mediated pathway in acute myeloid leukemia.
    El-Khazragy N; Ghozy S; Matbouly S; Zaki W; Safwat G; Hussien G; Khalifa O
    J Cell Biochem; 2019 Sep; 120(9):15288-15296. PubMed ID: 31038787
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Refined mapping of genomic rearrangements involving the short arm of chromosome 9 in acute lymphoblastic leukemias and other hematologic malignancies.
    Dreyling MH; Bohlander SK; Le Beau MM; Olopade OI
    Blood; 1995 Sep; 86(5):1931-8. PubMed ID: 7544647
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.