254 related articles for article (PubMed ID: 21422725)
1. Pathophysiological response to hypoxia - from the molecular mechanisms of malady to drug discovery: drug discovery for targeting the tumor microenvironment.
Nagasawa H
J Pharmacol Sci; 2011; 115(4):446-52. PubMed ID: 21422725
[TBL] [Abstract][Full Text] [Related]
2. Pathophysiological response to hypoxia - from the molecular mechanisms of malady to drug discovery:hypoxia-inducible factor-1 (HIF-1)-active cells as a target for cancer therapy.
Kizaka-Kondoh S; Kuchimaru T; Kadonosono T
J Pharmacol Sci; 2011; 115(4):440-5. PubMed ID: 21422727
[TBL] [Abstract][Full Text] [Related]
3. Hypoxia-directed drug strategies to target the tumor microenvironment.
Hay MP; Hicks KO; Wang J
Adv Exp Med Biol; 2014; 772():111-45. PubMed ID: 24272357
[TBL] [Abstract][Full Text] [Related]
4. Design of hypoxia-targeting drugs as new cancer chemotherapeutics.
Nagasawa H; Uto Y; Kirk KL; Hori H
Biol Pharm Bull; 2006 Dec; 29(12):2335-42. PubMed ID: 17142959
[TBL] [Abstract][Full Text] [Related]
5. Recent advances in hypoxia-inducible factor (HIF)-1 inhibitors.
Xia Y; Choi HK; Lee K
Eur J Med Chem; 2012 Mar; 49():24-40. PubMed ID: 22305612
[TBL] [Abstract][Full Text] [Related]
6. Pathophysiological response to hypoxia - from the molecular mechanisms of malady to drug discovery: epigenetic regulation of the hypoxic response via hypoxia-inducible factor and histone modifying enzymes.
Mimura I; Tanaka T; Wada Y; Kodama T; Nangaku M
J Pharmacol Sci; 2011; 115(4):453-8. PubMed ID: 21422728
[TBL] [Abstract][Full Text] [Related]
7. Cell physiology regulation by hypoxia inducible factor-1: Targeting oxygen-related nanomachineries of hypoxic cells.
Eskandani M; Vandghanooni S; Barar J; Nazemiyeh H; Omidi Y
Int J Biol Macromol; 2017 Jun; 99():46-62. PubMed ID: 28223135
[TBL] [Abstract][Full Text] [Related]
8. Development of HIF-1 inhibitors for cancer therapy.
Onnis B; Rapisarda A; Melillo G
J Cell Mol Med; 2009 Sep; 13(9A):2780-6. PubMed ID: 19674190
[TBL] [Abstract][Full Text] [Related]
9. Targeting tumor micro-environment for design and development of novel anti-angiogenic agents arresting tumor growth.
Gacche RN; Meshram RJ
Prog Biophys Mol Biol; 2013 Nov; 113(2):333-54. PubMed ID: 24139944
[TBL] [Abstract][Full Text] [Related]
10. Targeting hypoxia for sensitization of tumors to radio- and chemotherapy.
Ghattass K; Assah R; El-Sabban M; Gali-Muhtasib H
Curr Cancer Drug Targets; 2013 Jul; 13(6):670-85. PubMed ID: 23687923
[TBL] [Abstract][Full Text] [Related]
11. Hypoxia Induced ER Stress Response as an Adaptive Mechanism in Cancer.
Chipurupalli S; Kannan E; Tergaonkar V; D'Andrea R; Robinson N
Int J Mol Sci; 2019 Feb; 20(3):. PubMed ID: 30754624
[TBL] [Abstract][Full Text] [Related]
12. The intriguing interplay between therapies targeting the epidermal growth factor receptor, the hypoxic microenvironment and hypoxia-inducible factors.
Wouters A; Boeckx C; Vermorken JB; Van den Weyngaert D; Peeters M; Lardon F
Curr Pharm Des; 2013; 19(5):907-17. PubMed ID: 22973959
[TBL] [Abstract][Full Text] [Related]
13. Hypoxia-Induced Signaling Promotes Prostate Cancer Progression: Exosomes Role as Messenger of Hypoxic Response in Tumor Microenvironment.
Deep G; Panigrahi GK
Crit Rev Oncog; 2015; 20(5-6):419-34. PubMed ID: 27279239
[TBL] [Abstract][Full Text] [Related]
14. Hypoxia inducible factor in hepatocellular carcinoma: A therapeutic target.
Lin D; Wu J
World J Gastroenterol; 2015 Nov; 21(42):12171-8. PubMed ID: 26576101
[TBL] [Abstract][Full Text] [Related]
15. [Research progress of hypoxia-inducible factor 1 inhibitors against tumors].
Niu F; Li Y; Lai FF; Chen XG
Yao Xue Xue Bao; 2014 Jun; 49(6):832-6. PubMed ID: 25212028
[TBL] [Abstract][Full Text] [Related]
16. Hypoxia-inducible factor-1 in human breast and prostate cancer.
Kimbro KS; Simons JW
Endocr Relat Cancer; 2006 Sep; 13(3):739-49. PubMed ID: 16954428
[TBL] [Abstract][Full Text] [Related]
17. Cellular redox status regulates hypoxia inducible factor-1 activity. Role in tumour development.
Martínez-Sánchez G; Giuliani A
J Exp Clin Cancer Res; 2007 Mar; 26(1):39-50. PubMed ID: 17550131
[TBL] [Abstract][Full Text] [Related]
18. Recent Advances In Developing Novel Anti-Cancer Drugs Targeting Tumor Hypoxic and Acidic Microenvironments.
Li W; Sun X
Recent Pat Anticancer Drug Discov; 2018; 13(4):455-468. PubMed ID: 30173649
[TBL] [Abstract][Full Text] [Related]
19. Hypoxic Microenvironment and Metastatic Bone Disease.
Hiraga T
Int J Mol Sci; 2018 Nov; 19(11):. PubMed ID: 30423905
[TBL] [Abstract][Full Text] [Related]
20. Role of hypoxia in the hallmarks of human cancer.
Ruan K; Song G; Ouyang G
J Cell Biochem; 2009 Aug; 107(6):1053-62. PubMed ID: 19479945
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
