BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

278 related articles for article (PubMed ID: 21422728)

  • 1. Pathophysiological response to hypoxia - from the molecular mechanisms of malady to drug discovery: epigenetic regulation of the hypoxic response via hypoxia-inducible factor and histone modifying enzymes.
    Mimura I; Tanaka T; Wada Y; Kodama T; Nangaku M
    J Pharmacol Sci; 2011; 115(4):453-8. PubMed ID: 21422728
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Insights into The Function and Regulation of Jumonji C Lysine Demethylases as Hypoxic Responsive Enzymes.
    Chopra A; Adhikary H; Willmore WG; Biggar KK
    Curr Protein Pept Sci; 2020; 21(7):642-654. PubMed ID: 31889485
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate.
    Chakraborty AA; Laukka T; Myllykoski M; Ringel AE; Booker MA; Tolstorukov MY; Meng YJ; Meier SR; Jennings RB; Creech AL; Herbert ZT; McBrayer SK; Olenchock BA; Jaffe JD; Haigis MC; Beroukhim R; Signoretti S; Koivunen P; Kaelin WG
    Science; 2019 Mar; 363(6432):1217-1222. PubMed ID: 30872525
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Regulation of the histone demethylase JMJD1A by hypoxia-inducible factor 1 alpha enhances hypoxic gene expression and tumor growth.
    Krieg AJ; Rankin EB; Chan D; Razorenova O; Fernandez S; Giaccia AJ
    Mol Cell Biol; 2010 Jan; 30(1):344-53. PubMed ID: 19858293
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Epigenetic regulation by histone demethylases in hypoxia.
    Hancock RL; Dunne K; Walport LJ; Flashman E; Kawamura A
    Epigenomics; 2015 Aug; 7(5):791-811. PubMed ID: 25832587
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The histone demethylases JMJD1A and JMJD2B are transcriptional targets of hypoxia-inducible factor HIF.
    Beyer S; Kristensen MM; Jensen KS; Johansen JV; Staller P
    J Biol Chem; 2008 Dec; 283(52):36542-52. PubMed ID: 18984585
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hypoxic Regulation of Gene Transcription and Chromatin: Cause and Effect.
    Kindrick JD; Mole DR
    Int J Mol Sci; 2020 Nov; 21(21):. PubMed ID: 33171917
    [TBL] [Abstract][Full Text] [Related]  

  • 8. [Effect of Basil Polysaccharide on Histone H3K9me2 Methylation and Expression of G9a and JMJD1A in Hepatoma Cells Under Hypoxic Conditions].
    Feng B; Zhu Y; He SM; Zheng GJ; LIu Y; Zhu YZ
    Zhong Yao Cai; 2015 Jul; 38(7):1460-5. PubMed ID: 26946844
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hypoxia-Mediated Regulation of Histone Demethylases Affects Angiogenesis-Associated Functions in Endothelial Cells.
    Liu OH; Kiema M; Beter M; Ylä-Herttuala S; Laakkonen JP; Kaikkonen MU
    Arterioscler Thromb Vasc Biol; 2020 Nov; 40(11):2665-2677. PubMed ID: 32938217
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Integrative analysis of HIF binding and transactivation reveals its role in maintaining histone methylation homeostasis.
    Xia X; Lemieux ME; Li W; Carroll JS; Brown M; Liu XS; Kung AL
    Proc Natl Acad Sci U S A; 2009 Mar; 106(11):4260-5. PubMed ID: 19255431
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dynamic change of chromatin conformation in response to hypoxia enhances the expression of GLUT3 (SLC2A3) by cooperative interaction of hypoxia-inducible factor 1 and KDM3A.
    Mimura I; Nangaku M; Kanki Y; Tsutsumi S; Inoue T; Kohro T; Yamamoto S; Fujita T; Shimamura T; Suehiro J; Taguchi A; Kobayashi M; Tanimura K; Inagaki T; Tanaka T; Hamakubo T; Sakai J; Aburatani H; Kodama T; Wada Y
    Mol Cell Biol; 2012 Aug; 32(15):3018-32. PubMed ID: 22645302
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Histone H3K9 demethylase JMJD1A is a co-activator of erythropoietin expression under hypoxia.
    Tian Z; Yao L; Shen Y; Guo X; Duan X
    Int J Biochem Cell Biol; 2019 Apr; 109():33-39. PubMed ID: 30716474
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Role of hypoxia-inducible factors in epigenetic regulation via histone demethylases.
    Yang J; Ledaki I; Turley H; Gatter KC; Montero JC; Li JL; Harris AL
    Ann N Y Acad Sci; 2009 Oct; 1177():185-97. PubMed ID: 19845621
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Epigenetics, the epicenter of the hypoxic response.
    Watson JA; Watson CJ; McCann A; Baugh J
    Epigenetics; 2010 May; 5(4):293-6. PubMed ID: 20418669
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Gene regulation by histone-modifying enzymes under hypoxic conditions: a focus on histone methylation and acetylation.
    Kim J; Lee H; Yi SJ; Kim K
    Exp Mol Med; 2022 Jul; 54(7):878-889. PubMed ID: 35869366
    [TBL] [Abstract][Full Text] [Related]  

  • 16. HIF-1α-induced histone demethylase JMJD2B contributes to the malignant phenotype of colorectal cancer cells via an epigenetic mechanism.
    Fu L; Chen L; Yang J; Ye T; Chen Y; Fang J
    Carcinogenesis; 2012 Sep; 33(9):1664-73. PubMed ID: 22745382
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Epigenetic regulation of hypoxia inducible factor in diseases and therapeutics.
    Nguyen MP; Lee S; Lee YM
    Arch Pharm Res; 2013 Mar; 36(3):252-63. PubMed ID: 23440580
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Intermittent hypoxia enhances the expression of hypoxia inducible factor HIF1A through histone demethylation.
    Martinez CA; Jiramongkol Y; Bal N; Alwis I; Nedoboy PE; Farnham MMJ; White MD; Cistulli PA; Cook KM
    J Biol Chem; 2022 Nov; 298(11):102536. PubMed ID: 36174675
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Hypoxia-driven epigenetic regulation in cancer progression: A focus on histone methylation and its modifying enzymes.
    Kim I; Park JW
    Cancer Lett; 2020 Oct; 489():41-49. PubMed ID: 32522693
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inflammation, HIF-1, and the epigenetics that follows.
    Brigati C; Banelli B; di Vinci A; Casciano I; Allemanni G; Forlani A; Borzì L; Romani M
    Mediators Inflamm; 2010; 2010():263914. PubMed ID: 21197398
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.