These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

181 related articles for article (PubMed ID: 21430599)

  • 1. The farnesyltransferase inhibitors tipifarnib and lonafarnib inhibit cytokines secretion in a cellular model of mevalonate kinase deficiency.
    Marcuzzi A; De Leo L; Decorti G; Crovella S; Tommasini A; Pontillo A
    Pediatr Res; 2011 Jul; 70(1):78-82. PubMed ID: 21430599
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Targeting farnesyl-transferase as a novel therapeutic strategy for mevalonate kinase deficiency: in vitro and in vivo approaches.
    De Leo L; Marcuzzi A; Decorti G; Tommasini A; Crovella S; Pontillo A
    Pharmacol Res; 2010 Jun; 61(6):506-10. PubMed ID: 20206266
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Natural isoprenoids inhibit LPS-induced-production of cytokines and nitric oxide in aminobisphosphonate-treated monocytes.
    Marcuzzi A; Tommasini A; Crovella S; Pontillo A
    Int Immunopharmacol; 2010 Jun; 10(6):639-42. PubMed ID: 20304105
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Geraniol rescues inflammation in cellular and animal models of mevalonate kinase deficiency.
    Marcuzzi A; Crovella S; Pontillo A
    In Vivo; 2011; 25(1):87-92. PubMed ID: 21282739
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Temperature and drug treatments in mevalonate kinase deficiency: an ex vivo study.
    Tricarico PM; Kleiner G; Piscianz E; Zanin V; Monasta L; Crovella S; Marcuzzi A
    Biomed Res Int; 2013; 2013():715465. PubMed ID: 24073415
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Specific increase in caspase-1 activity and secretion of IL-1 family cytokines: a putative link between mevalonate kinase deficiency and inflammation.
    Normand S; Massonnet B; Delwail A; Favot L; Cuisset L; Grateau G; Morel F; Silvain C; Lecron JC
    Eur Cytokine Netw; 2009 Sep; 20(3):101-7. PubMed ID: 19825518
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Alendronate, a double-edged sword acting in the mevalonate pathway.
    Tricarico PM; Girardelli M; Kleiner G; Knowles A; Valencic E; Crovella S; Marcuzzi A
    Mol Med Rep; 2015 Sep; 12(3):4238-4242. PubMed ID: 26096667
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Repositioning of Tak-475 In Mevalonate Kinase Disease: Translating Theory Into Practice.
    Marcuzzi A; Loganes C; Celeghini C; Kleiner G
    Curr Med Chem; 2018; 25(24):2783-2796. PubMed ID: 28901277
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A role for geranylgeranylation in interleukin-1beta secretion.
    Mandey SH; Kuijk LM; Frenkel J; Waterham HR
    Arthritis Rheum; 2006 Nov; 54(11):3690-5. PubMed ID: 17075828
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mevalonate Kinase Deficiency and Squalene Synthase Inhibitor (TAK-475): The Balance to Extinguish the Inflammation.
    Rimondi E; Valencic E; Tommasini A; Secchiero P; Melloni E; Marcuzzi A
    Biomolecules; 2021 Sep; 11(10):. PubMed ID: 34680069
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Anti-inflammatory activity in vitro and in vivo of the protein farnesyltransferase inhibitor tipifarnib.
    Xue X; Lai KT; Huang JF; Gu Y; Karlsson L; Fourie A
    J Pharmacol Exp Ther; 2006 Apr; 317(1):53-60. PubMed ID: 16352705
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Natural isoprenoids are able to reduce inflammation in a mouse model of mevalonate kinase deficiency.
    Marcuzzi A; Pontillo A; De Leo L; Tommasini A; Decorti G; Not T; Ventura A
    Pediatr Res; 2008 Aug; 64(2):177-82. PubMed ID: 18391837
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mouse model of mevalonate kinase deficiency: comparison of cytokine and chemokine profile with that of human patients.
    Marcuzzi A; Zanin V; Kleiner G; Monasta L; Crovella S
    Pediatr Res; 2013 Sep; 74(3):266-71. PubMed ID: 23760140
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Lack of isoprenoid products raises ex vivo interleukin-1beta secretion in hyperimmunoglobulinemia D and periodic fever syndrome.
    Frenkel J; Rijkers GT; Mandey SH; Buurman SW; Houten SM; Wanders RJ; Waterham HR; Kuis W
    Arthritis Rheum; 2002 Oct; 46(10):2794-803. PubMed ID: 12384940
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Autophagy induced by farnesyltransferase inhibitors in cancer cells.
    Pan J; Chen B; Su CH; Zhao R; Xu ZX; Sun L; Lee MH; Yeung SC
    Cancer Biol Ther; 2008 Oct; 7(10):1679-84. PubMed ID: 18769123
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Defect in mevalonate pathway induces pyroptosis in Raw 264.7 murine monocytes.
    Marcuzzi A; Piscianz E; Girardelli M; Crovella S; Pontillo A
    Apoptosis; 2011 Sep; 16(9):882-8. PubMed ID: 21667041
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Bioactivity of Farnesyltransferase Inhibitors Against
    Probst A; Nguyen TN; El-Sakkary N; Skinner D; Suzuki BM; Buckner FS; Gelb MH; Caffrey CR; Debnath A
    Front Cell Infect Microbiol; 2019; 9():180. PubMed ID: 31192168
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Monocyte Production of IFN-γ Is Interleukin-12 Dependent in a Model of Mevalonate Kinase Deficiency.
    Frey T; Swade K; Zwecker L; Llewellyn T; Vogt E; Monteferante K; English H
    J Interferon Cytokine Res; 2019 Jun; 39(6):364-374. PubMed ID: 31013450
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mevalonate kinase deficiency leads to decreased prenylation of Rab GTPases.
    Jurczyluk J; Munoz MA; Skinner OP; Chai RC; Ali N; Palendira U; Quinn JM; Preston A; Tangye SG; Brown AJ; Argent E; Ziegler JB; Mehr S; Rogers MJ
    Immunol Cell Biol; 2016 Nov; 94(10):994-999. PubMed ID: 27377765
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Farnesyltransferase inihibitors in hematologic malignancies.
    Harousseau JL
    Blood Rev; 2007 Jul; 21(4):173-82. PubMed ID: 17293017
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.