These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

94 related articles for article (PubMed ID: 21435388)

  • 1. Characterization of enzyme activities of Cytochrome P450 enzymes, Flavin-dependent monooxygenases, N-acetyltransferases and UDP-glucuronyltransferases in human reconstructed epidermis and full-thickness skin models.
    Jäckh C; Blatz V; Fabian E; Guth K; van Ravenzwaay B; Reisinger K; Landsiedel R
    Toxicol In Vitro; 2011 Sep; 25(6):1209-14. PubMed ID: 21435388
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Xenobiotic metabolism gene expression in the EpiDermin vitro 3D human epidermis model compared to human skin.
    Hu T; Khambatta ZS; Hayden PJ; Bolmarcich J; Binder RL; Robinson MK; Carr GJ; Tiesman JP; Jarrold BB; Osborne R; Reichling TD; Nemeth ST; Aardema MJ
    Toxicol In Vitro; 2010 Aug; 24(5):1450-63. PubMed ID: 20350595
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Xenobiotic metabolism capacities of human skin in comparison with a 3D-epidermis model and keratinocyte-based cell culture as in vitro alternatives for chemical testing: phase II enzymes.
    Götz C; Pfeiffer R; Tigges J; Ruwiedel K; Hübenthal U; Merk HF; Krutmann J; Edwards RJ; Abel J; Pease C; Goebel C; Hewitt N; Fritsche E
    Exp Dermatol; 2012 May; 21(5):364-9. PubMed ID: 22509834
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Xenobiotic metabolism capacities of human skin in comparison with a 3D epidermis model and keratinocyte-based cell culture as in vitro alternatives for chemical testing: activating enzymes (Phase I).
    Götz C; Pfeiffer R; Tigges J; Blatz V; Jäckh C; Freytag EM; Fabian E; Landsiedel R; Merk HF; Krutmann J; Edwards RJ; Pease C; Goebel C; Hewitt N; Fritsche E
    Exp Dermatol; 2012 May; 21(5):358-63. PubMed ID: 22509833
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Expression and activities of several drug-metabolizing enzymes in LLC-PK1 cells.
    Gonzalez RJ; Tarloff JB
    Toxicol In Vitro; 2004 Dec; 18(6):887-94. PubMed ID: 15465656
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Expression profiles of phases 1 and 2 metabolizing enzymes in human skin and the reconstructed skin models Episkin and full thickness model from Episkin.
    Luu-The V; Duche D; Ferraris C; Meunier JR; Leclaire J; Labrie F
    J Steroid Biochem Mol Biol; 2009 Sep; 116(3-5):178-86. PubMed ID: 19482084
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Expression and induction of cytochrome p450 isoenzymes in human skin equivalents.
    Neis MM; Wendel A; Wiederholt T; Marquardt Y; Joussen S; Baron JM; Merk HF
    Skin Pharmacol Physiol; 2010; 23(1):29-39. PubMed ID: 20090406
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Comparison of xenobiotic metabolizing enzyme activities in ex vivo human skin and reconstructed human skin models from SkinEthic.
    Eilstein J; Léreaux G; Budimir N; Hussler G; Wilkinson S; Duché D
    Arch Toxicol; 2014 Sep; 88(9):1681-1694. PubMed ID: 24658324
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Characterization of microsomal cytochrome P450 enzymes involved in the oxidation of xenobiotic chemicals in human fetal liver and adult lungs.
    Shimada T; Yamazaki H; Mimura M; Wakamiya N; Ueng YF; Guengerich FP; Inui Y
    Drug Metab Dispos; 1996 May; 24(5):515-22. PubMed ID: 8723730
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Biotransformation of drugs in human skin.
    Svensson CK
    Drug Metab Dispos; 2009 Feb; 37(2):247-53. PubMed ID: 19005027
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Some distinctions between flavin-containing and cytochrome P450 monooxygenases.
    Cashman JR
    Biochem Biophys Res Commun; 2005 Dec; 338(1):599-604. PubMed ID: 16112078
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Quantification and cellular localization of expression in human skin of genes encoding flavin-containing monooxygenases and cytochromes P450.
    Janmohamed A; Dolphin CT; Phillips IR; Shephard EA
    Biochem Pharmacol; 2001 Sep; 62(6):777-86. PubMed ID: 11551524
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Use of human in vitro skin models for accurate and ethical risk assessment: metabolic considerations.
    Hewitt NJ; Edwards RJ; Fritsche E; Goebel C; Aeby P; Scheel J; Reisinger K; Ouédraogo G; Duche D; Eilstein J; Latil A; Kenny J; Moore C; Kuehnl J; Barroso J; Fautz R; Pfuhler S
    Toxicol Sci; 2013 Jun; 133(2):209-17. PubMed ID: 23539547
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Studies on microsomal cytochrome P-450, monooxygenases and epoxide hydrolase in cultured keratinocytes and intact epidermis from BALB/C mice.
    Bickers DR; Marcelo CL; Dutta-Choudhury T; Mukhtar H
    J Pharmacol Exp Ther; 1982 Oct; 223(1):163-8. PubMed ID: 7120116
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Metabolism of dipropyl disulfide by rat liver phase I and phase II enzymes and by isolated perfused rat liver.
    Teyssier C; Siess MH
    Drug Metab Dispos; 2000 Jun; 28(6):648-54. PubMed ID: 10820136
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effects of the differentiated keratinocyte phenotype on expression levels of CYP1-4 family genes in human skin cells.
    Du L; Neis MM; Ladd PA; Lanza DL; Yost GS; Keeney DS
    Toxicol Appl Pharmacol; 2006 Jun; 213(2):135-44. PubMed ID: 16307767
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The participation of human hepatic P450 isoforms, flavin-containing monooxygenases and aldehyde oxidase in the biotransformation of the insecticide fenthion.
    Leoni C; Buratti FM; Testai E
    Toxicol Appl Pharmacol; 2008 Dec; 233(2):343-52. PubMed ID: 18845175
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Xenobiotic metabolizing enzyme activities in cells used for testing skin sensitization in vitro.
    Fabian E; Vogel D; Blatz V; Ramirez T; Kolle S; Eltze T; van Ravenzwaay B; Oesch F; Landsiedel R
    Arch Toxicol; 2013 Sep; 87(9):1683-96. PubMed ID: 23958860
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Comparisons of phase I and phase II in vitro hepatic enzyme activities of human, dog, rhesus monkey, and cynomolgus monkey.
    Sharer JE; Shipley LA; Vandenbranden MR; Binkley SN; Wrighton SA
    Drug Metab Dispos; 1995 Nov; 23(11):1231-41. PubMed ID: 8591724
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Activities of drug metabolizing enzymes in bovine colon epithelial cell cultures.
    Birkner S; Weber S; Dohle A; Schmahl G; Bolt HM; Föllmann W
    Arch Toxicol; 2003 Nov; 77(11):621-9. PubMed ID: 14508638
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.