259 related articles for article (PubMed ID: 21441348)
1. Prp8, the pivotal protein of the spliceosomal catalytic center, evolved from a retroelement-encoded reverse transcriptase.
Dlakić M; Mushegian A
RNA; 2011 May; 17(5):799-808. PubMed ID: 21441348
[TBL] [Abstract][Full Text] [Related]
2. Structural dynamics of the N-terminal domain and the Switch loop of Prp8 during spliceosome assembly and activation.
Jia X; Sun C
Nucleic Acids Res; 2018 May; 46(8):3833-3840. PubMed ID: 29635373
[TBL] [Abstract][Full Text] [Related]
3. A close-up look at the spliceosome, at last.
Abelson J
Proc Natl Acad Sci U S A; 2017 Apr; 114(17):4288-4293. PubMed ID: 28408394
[TBL] [Abstract][Full Text] [Related]
4. Mutations in the U5 snRNA result in altered splicing of subsets of pre-mRNAs and reduced stability of Prp8.
Kershaw CJ; Barrass JD; Beggs JD; O'Keefe RT
RNA; 2009 Jul; 15(7):1292-304. PubMed ID: 19447917
[TBL] [Abstract][Full Text] [Related]
5. Crystal structure of Prp8 reveals active site cavity of the spliceosome.
Galej WP; Oubridge C; Newman AJ; Nagai K
Nature; 2013 Jan; 493(7434):638-43. PubMed ID: 23354046
[TBL] [Abstract][Full Text] [Related]
6. An unanticipated early function of DEAD-box ATPase Prp28 during commitment to splicing is modulated by U5 snRNP protein Prp8.
Price AM; Görnemann J; Guthrie C; Brow DA
RNA; 2014 Jan; 20(1):46-60. PubMed ID: 24231520
[TBL] [Abstract][Full Text] [Related]
7. The Prp8 RNase H-like domain inhibits Brr2-mediated U4/U6 snRNA unwinding by blocking Brr2 loading onto the U4 snRNA.
Mozaffari-Jovin S; Santos KF; Hsiao HH; Will CL; Urlaub H; Wahl MC; Lührmann R
Genes Dev; 2012 Nov; 26(21):2422-34. PubMed ID: 23124066
[TBL] [Abstract][Full Text] [Related]
8. Physical and genetic interactions of yeast Cwc21p, an ortholog of human SRm300/SRRM2, suggest a role at the catalytic center of the spliceosome.
Grainger RJ; Barrass JD; Jacquier A; Rain JC; Beggs JD
RNA; 2009 Dec; 15(12):2161-73. PubMed ID: 19854871
[TBL] [Abstract][Full Text] [Related]
9. Comprehensive in vivo RNA-binding site analyses reveal a role of Prp8 in spliceosomal assembly.
Li X; Zhang W; Xu T; Ramsey J; Zhang L; Hill R; Hansen KC; Hesselberth JR; Zhao R
Nucleic Acids Res; 2013 Apr; 41(6):3805-18. PubMed ID: 23393194
[TBL] [Abstract][Full Text] [Related]
10. Structural toggle in the RNaseH domain of Prp8 helps balance splicing fidelity and catalytic efficiency.
Mayerle M; Raghavan M; Ledoux S; Price A; Stepankiw N; Hadjivassiliou H; Moehle EA; Mendoza SD; Pleiss JA; Guthrie C; Abelson J
Proc Natl Acad Sci U S A; 2017 May; 114(18):4739-4744. PubMed ID: 28416677
[TBL] [Abstract][Full Text] [Related]
11. Prp8 positioning of U5 snRNA is linked to 5' splice site recognition.
MacRae AJ; Mayerle M; Hrabeta-Robinson E; Chalkley RJ; Guthrie C; Burlingame AL; Jurica MS
RNA; 2018 Jun; 24(6):769-777. PubMed ID: 29487104
[TBL] [Abstract][Full Text] [Related]
12. Structural evidence for consecutive Hel308-like modules in the spliceosomal ATPase Brr2.
Zhang L; Xu T; Maeder C; Bud LO; Shanks J; Nix J; Guthrie C; Pleiss JA; Zhao R
Nat Struct Mol Biol; 2009 Jul; 16(7):731-9. PubMed ID: 19525970
[TBL] [Abstract][Full Text] [Related]
13. Structure of a spliceosome remodelled for exon ligation.
Fica SM; Oubridge C; Galej WP; Wilkinson ME; Bai XC; Newman AJ; Nagai K
Nature; 2017 Feb; 542(7641):377-380. PubMed ID: 28076345
[TBL] [Abstract][Full Text] [Related]
14. The U5 snRNA internal loop 1 is a platform for Brr2, Snu114 and Prp8 protein binding during U5 snRNP assembly.
Nancollis V; Ruckshanthi JP; Frazer LN; O'Keefe RT
J Cell Biochem; 2013 Dec; 114(12):2770-84. PubMed ID: 23857713
[TBL] [Abstract][Full Text] [Related]
15. How Is Precursor Messenger RNA Spliced by the Spliceosome?
Wan R; Bai R; Zhan X; Shi Y
Annu Rev Biochem; 2020 Jun; 89():333-358. PubMed ID: 31815536
[TBL] [Abstract][Full Text] [Related]
16. Dissection of Prp8 protein defines multiple interactions with crucial RNA sequences in the catalytic core of the spliceosome.
Turner IA; Norman CM; Churcher MJ; Newman AJ
RNA; 2006 Mar; 12(3):375-86. PubMed ID: 16431982
[TBL] [Abstract][Full Text] [Related]
17. Localization of Prp8, Brr2, Snu114 and U4/U6 proteins in the yeast tri-snRNP by electron microscopy.
Häcker I; Sander B; Golas MM; Wolf E; Karagöz E; Kastner B; Stark H; Fabrizio P; Lührmann R
Nat Struct Mol Biol; 2008 Nov; 15(11):1206-12. PubMed ID: 18953335
[TBL] [Abstract][Full Text] [Related]
18. CEF1/CDC5 alleles modulate transitions between catalytic conformations of the spliceosome.
Query CC; Konarska MM
RNA; 2012 May; 18(5):1001-13. PubMed ID: 22408182
[TBL] [Abstract][Full Text] [Related]
19. Structural elucidation of a PRP8 core domain from the heart of the spliceosome.
Ritchie DB; Schellenberg MJ; Gesner EM; Raithatha SA; Stuart DT; Macmillan AM
Nat Struct Mol Biol; 2008 Nov; 15(11):1199-205. PubMed ID: 18836455
[TBL] [Abstract][Full Text] [Related]
20. The splicing factor Prp17 interacts with the U2, U5 and U6 snRNPs and associates with the spliceosome pre- and post-catalysis.
Sapra AK; Khandelia P; Vijayraghavan U
Biochem J; 2008 Dec; 416(3):365-74. PubMed ID: 18691155
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
