These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

281 related articles for article (PubMed ID: 21441914)

  • 1. ABC ATPase signature helices in Rad50 link nucleotide state to Mre11 interface for DNA repair.
    Williams GJ; Williams RS; Williams JS; Moncalian G; Arvai AS; Limbo O; Guenther G; SilDas S; Hammel M; Russell P; Tainer JA
    Nat Struct Mol Biol; 2011 Apr; 18(4):423-31. PubMed ID: 21441914
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural biochemistry and interaction architecture of the DNA double-strand break repair Mre11 nuclease and Rad50-ATPase.
    Hopfner KP; Karcher A; Craig L; Woo TT; Carney JP; Tainer JA
    Cell; 2001 May; 105(4):473-85. PubMed ID: 11371344
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Rad50 zinc-hook is a structure joining Mre11 complexes in DNA recombination and repair.
    Hopfner KP; Craig L; Moncalian G; Zinkel RA; Usui T; Owen BA; Karcher A; Henderson B; Bodmer JL; McMurray CT; Carney JP; Petrini JH; Tainer JA
    Nature; 2002 Aug; 418(6897):562-6. PubMed ID: 12152085
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The rad50 signature motif: essential to ATP binding and biological function.
    Moncalian G; Lengsfeld B; Bhaskara V; Hopfner KP; Karcher A; Alden E; Tainer JA; Paull TT
    J Mol Biol; 2004 Jan; 335(4):937-51. PubMed ID: 14698290
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Crystal structure of the Mre11-Rad50-ATPγS complex: understanding the interplay between Mre11 and Rad50.
    Lim HS; Kim JS; Park YB; Gwon GH; Cho Y
    Genes Dev; 2011 May; 25(10):1091-104. PubMed ID: 21511873
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repair.
    Limbo O; Moiani D; Kertokalio A; Wyman C; Tainer JA; Russell P
    Nucleic Acids Res; 2012 Dec; 40(22):11435-49. PubMed ID: 23080121
    [TBL] [Abstract][Full Text] [Related]  

  • 7. ATP driven structural changes of the bacterial Mre11:Rad50 catalytic head complex.
    Möckel C; Lammens K; Schele A; Hopfner KP
    Nucleic Acids Res; 2012 Jan; 40(2):914-27. PubMed ID: 21937514
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A rod conformation of the Pyrococcus furiosus Rad50 coiled coil.
    Soh YM; Basquin J; Gruber S
    Proteins; 2021 Feb; 89(2):251-255. PubMed ID: 32875643
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Adjacent mutations in the archaeal Rad50 ABC ATPase D-loop disrupt allosteric regulation of ATP hydrolysis through different mechanisms.
    Boswell ZK; Canny MD; Buschmann TA; Sang J; Latham MP
    Nucleic Acids Res; 2020 Mar; 48(5):2457-2472. PubMed ID: 31889185
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Rad50 adenylate kinase activity regulates DNA tethering by Mre11/Rad50 complexes.
    Bhaskara V; Dupré A; Lengsfeld B; Hopkins BB; Chan A; Lee JH; Zhang X; Gautier J; Zakian V; Paull TT
    Mol Cell; 2007 Mar; 25(5):647-61. PubMed ID: 17349953
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Autoinhibition of bacteriophage T4 Mre11 by its C-terminal domain.
    Gao Y; Nelson SW
    J Biol Chem; 2014 Sep; 289(38):26505-26513. PubMed ID: 25077970
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The Mre11:Rad50 structure shows an ATP-dependent molecular clamp in DNA double-strand break repair.
    Lammens K; Bemeleit DJ; Möckel C; Clausing E; Schele A; Hartung S; Schiller CB; Lucas M; Angermüller C; Söding J; Strässer K; Hopfner KP
    Cell; 2011 Apr; 145(1):54-66. PubMed ID: 21458667
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mre11 dimers coordinate DNA end bridging and nuclease processing in double-strand-break repair.
    Williams RS; Moncalian G; Williams JS; Yamada Y; Limbo O; Shin DS; Groocock LM; Cahill D; Hitomi C; Guenther G; Moiani D; Carney JP; Russell P; Tainer JA
    Cell; 2008 Oct; 135(1):97-109. PubMed ID: 18854158
    [TBL] [Abstract][Full Text] [Related]  

  • 14. ATP hydrolysis by RAD50 protein switches MRE11 enzyme from endonuclease to exonuclease.
    Majka J; Alford B; Ausio J; Finn RM; McMurray CT
    J Biol Chem; 2012 Jan; 287(4):2328-41. PubMed ID: 22102415
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Modes of action of the archaeal Mre11/Rad50 DNA-repair complex revealed by fast-scan atomic force microscopy.
    Zabolotnaya E; Mela I; Williamson MJ; Bray SM; Yau SK; Papatziamou D; Edwardson JM; Robinson NP; Henderson RM
    Proc Natl Acad Sci U S A; 2020 Jun; 117(26):14936-14947. PubMed ID: 32541055
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Molecular characterization of the Schizosaccharomyces pombe nbs1+ gene involved in DNA repair and telomere maintenance.
    Ueno M; Nakazaki T; Akamatsu Y; Watanabe K; Tomita K; Lindsay HD; Shinagawa H; Iwasaki H
    Mol Cell Biol; 2003 Sep; 23(18):6553-63. PubMed ID: 12944481
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mre11 and Rad50 from Pyrococcus furiosus: cloning and biochemical characterization reveal an evolutionarily conserved multiprotein machine.
    Hopfner KP; Karcher A; Shin D; Fairley C; Tainer JA; Carney JP
    J Bacteriol; 2000 Nov; 182(21):6036-41. PubMed ID: 11029422
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Regulation of Mre11/Rad50 by Nbs1: effects on nucleotide-dependent DNA binding and association with ataxia-telangiectasia-like disorder mutant complexes.
    Lee JH; Ghirlando R; Bhaskara V; Hoffmeyer MR; Gu J; Paull TT
    J Biol Chem; 2003 Nov; 278(46):45171-81. PubMed ID: 12966088
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Turning the Mre11/Rad50 DNA repair complex on its head: lessons from SMC protein hinges, dynamic coiled-coil movements and DNA loop-extrusion?
    Zabolotnaya E; Mela I; Henderson RM; Robinson NP
    Biochem Soc Trans; 2020 Dec; 48(6):2359-2376. PubMed ID: 33300987
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Post-translational methylations of the archaeal Mre11:Rad50 complex throughout the DNA damage response.
    Kish A; Gaillard JC; Armengaud J; Elie C
    Mol Microbiol; 2016 Apr; 100(2):362-78. PubMed ID: 26724682
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.