166 related articles for article (PubMed ID: 21443218)
1. Analogues and derivatives of oncrasin-1, a novel inhibitor of the C-terminal domain of RNA polymerase II and their antitumor activities.
Wu S; Wang L; Guo W; Liu X; Liu J; Wei X; Fang B
J Med Chem; 2011 Apr; 54(8):2668-79. PubMed ID: 21443218
[TBL] [Abstract][Full Text] [Related]
2. Antitumor activity of a novel oncrasin analogue is mediated by JNK activation and STAT3 inhibition.
Guo W; Wu S; Wang L; Wei X; Liu X; Wang J; Lu Z; Hollingshead M; Fang B
PLoS One; 2011; 6(12):e28487. PubMed ID: 22174819
[TBL] [Abstract][Full Text] [Related]
3. Interruption of RNA processing machinery by a small compound, 1-[(4-chlorophenyl)methyl]-1H-indole-3-carboxaldehyde (oncrasin-1).
Guo W; Wu S; Wang L; Wang RY; Wei X; Liu J; Fang B
Mol Cancer Ther; 2009 Feb; 8(2):441-8. PubMed ID: 19208825
[TBL] [Abstract][Full Text] [Related]
4. Identification of a small molecule with synthetic lethality for K-ras and protein kinase C iota.
Guo W; Wu S; Liu J; Fang B
Cancer Res; 2008 Sep; 68(18):7403-8. PubMed ID: 18794128
[TBL] [Abstract][Full Text] [Related]
5. Indole amide hydroxamic acids as potent inhibitors of histone deacetylases.
Dai Y; Guo Y; Guo J; Pease LJ; Li J; Marcotte PA; Glaser KB; Tapang P; Albert DH; Richardson PL; Davidsen SK; Michaelides MR
Bioorg Med Chem Lett; 2003 Jun; 13(11):1897-901. PubMed ID: 12749893
[TBL] [Abstract][Full Text] [Related]
6. Cytotoxicity and DNA topoisomerase inhibitory activity of benz[f]indole-4,9-dione analogs.
Park HJ; Lee HJ; Lee EJ; Hwang HJ; Shin SH; Suh ME; Kim C; Kim HJ; Seo EK; Lee SK
Biosci Biotechnol Biochem; 2003 Sep; 67(9):1944-9. PubMed ID: 14519980
[TBL] [Abstract][Full Text] [Related]
7. Prodrug oncrasin-266 improves the stability, pharmacokinetics, and safety of NSC-743380.
Wu S; Wang L; Huang X; Cao M; Hu J; Li H; Zhang H; Sun X; Meng QH; Hofstetter WL; Roth JA; Swisher SG; Fang B
Bioorg Med Chem; 2014 Oct; 22(19):5234-40. PubMed ID: 25182964
[TBL] [Abstract][Full Text] [Related]
8. Simultaneous determination and validation of oncrasin-266 and its metabolites by HPLC-MS/MS: Application to a pharmacokinetic study.
White L; Wu S; Ma J; Fang B; Liang D
J Chromatogr B Analyt Technol Biomed Life Sci; 2016 Oct; 1033-1034():106-111. PubMed ID: 27541624
[TBL] [Abstract][Full Text] [Related]
9. Synthesis and pharmacological evaluation of novel bisindolylalkanes analogues.
Song YL; Dong YF; Yang T; Zhang CC; Su LM; Huang X; Zhang DN; Yang GL; Liu YX
Bioorg Med Chem; 2013 Dec; 21(24):7624-7. PubMed ID: 24262885
[TBL] [Abstract][Full Text] [Related]
10. Synthesis and Cytotoxic Activity of Novel Mono- and Bis-Indole Derivatives: Analogues of Marine Alkaloid Nortopsentin.
Kamel MM; Abdel-Hameid MK; El-Nassan HB; El-Khouly EA
Med Chem; 2021; 17(7):779-789. PubMed ID: 32386499
[TBL] [Abstract][Full Text] [Related]
11. Indole-3-carbinol (I3C) analogues are potent small molecule inhibitors of NEDD4-1 ubiquitin ligase activity that disrupt proliferation of human melanoma cells.
Quirit JG; Lavrenov SN; Poindexter K; Xu J; Kyauk C; Durkin KA; Aronchik I; Tomasiak T; Solomatin YA; Preobrazhenskaya MN; Firestone GL
Biochem Pharmacol; 2017 Mar; 127():13-27. PubMed ID: 27979631
[TBL] [Abstract][Full Text] [Related]
12. 1,2,3-triazole tethered Indole-3-glyoxamide derivatives as multiple inhibitors of 5-LOX, COX-2 & tubulin: Their anti-proliferative & anti-inflammatory activity.
Naaz F; Preeti Pallavi MC; Shafi S; Mulakayala N; Shahar Yar M; Sampath Kumar HM
Bioorg Chem; 2018 Dec; 81():1-20. PubMed ID: 30081353
[TBL] [Abstract][Full Text] [Related]
13. Structural optimization of indole based compounds for highly promising anti-cancer activities: structure activity relationship studies and identification of lead molecules.
Shaveta ; Singh P
Eur J Med Chem; 2014 Mar; 74():440-50. PubMed ID: 24487192
[TBL] [Abstract][Full Text] [Related]
14. Synthesis and cytotoxic activities of a series of novel N-methyl-bisindolylmaleimide amide derivatives.
Wang K; Liu ZZ
J Asian Nat Prod Res; 2014; 16(3):296-303. PubMed ID: 24456252
[TBL] [Abstract][Full Text] [Related]
15. Paullones, a series of cyclin-dependent kinase inhibitors: synthesis, evaluation of CDK1/cyclin B inhibition, and in vitro antitumor activity.
Schultz C; Link A; Leost M; Zaharevitz DW; Gussio R; Sausville EA; Meijer L; Kunick C
J Med Chem; 1999 Jul; 42(15):2909-19. PubMed ID: 10425100
[TBL] [Abstract][Full Text] [Related]
16. Design, synthesis, in vitro antiproliferative activity and apoptosis-inducing studies of 1-(3',4',5'-trimethoxyphenyl)-3-(2'-alkoxycarbonylindolyl)-2-propen-1-one derivatives obtained by a molecular hybridisation approach.
Preti D; Romagnoli R; Rondanin R; Cacciari B; Hamel E; Balzarini J; Liekens S; Schols D; Estévez-Sarmiento F; Quintana J; Estévez F
J Enzyme Inhib Med Chem; 2018 Dec; 33(1):1225-1238. PubMed ID: 30141353
[TBL] [Abstract][Full Text] [Related]
17. Novel 5-azaindolocarbazoles as cytotoxic agents and Chk1 inhibitors.
Lefoix M; Coudert G; Routier S; Pfeiffer B; Caignard DH; Hickman J; Pierré A; Golsteyn RM; Léonce S; Bossard C; Mérour JY
Bioorg Med Chem; 2008 May; 16(9):5303-21. PubMed ID: 18342518
[TBL] [Abstract][Full Text] [Related]
18. Antitumor effects of synthetic 6,7-annulated-4-substituted indole compounds in L1210 leukemic cells in vitro.
Perchellet JP; Waters AM; Perchellet EM; Thornton PD; Brown N; Hill D; Neuenswander B; Lushington GH; Santini C; Chandrasoma N; Buszek KR
Anticancer Res; 2012 Nov; 32(11):4671-84. PubMed ID: 23155229
[TBL] [Abstract][Full Text] [Related]
19. Structure-activity relationship analysis of the peptide deformylase inhibitor 5-bromo-1H-indole-3-acetohydroxamic acid.
Petit S; Duroc Y; Larue V; Giglione C; Léon C; Soulama C; Denis A; Dardel F; Meinnel T; Artaud I
ChemMedChem; 2009 Feb; 4(2):261-75. PubMed ID: 19053131
[TBL] [Abstract][Full Text] [Related]
20. Tyrosine kinase inhibitors. 6. Structure-activity relationships among N- and 3-substituted 2,2'-diselenobis(1H-indoles) for inhibition of protein tyrosine kinases and comparative in vitro and in vivo studies against selected sulfur congeners.
Showalter HD; Sercel AD; Leja BM; Wolfangel CD; Ambroso LA; Elliott WL; Fry DW; Kraker AJ; Howard CT; Lu GH; Moore CW; Nelson JM; Roberts BJ; Vincent PW; Denny WA; Thompson AM
J Med Chem; 1997 Feb; 40(4):413-26. PubMed ID: 9046331
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]