242 related articles for article (PubMed ID: 21445305)
1. Regulation of AKT phosphorylation at Ser473 and Thr308 by endoplasmic reticulum stress modulates substrate specificity in a severity dependent manner.
Yung HW; Charnock-Jones DS; Burton GJ
PLoS One; 2011 Mar; 6(3):e17894. PubMed ID: 21445305
[TBL] [Abstract][Full Text] [Related]
2. AKT phosphorylation sites of Ser473 and Thr308 regulate AKT degradation.
Wei Y; Zhou J; Yu H; Jin X
Biosci Biotechnol Biochem; 2019 Mar; 83(3):429-435. PubMed ID: 30488766
[TBL] [Abstract][Full Text] [Related]
3. Tamoxifen-induced cytotoxicity in breast cancer cells is mediated by glucose-regulated protein 78 (GRP78) via AKT (Thr308) regulation.
Pujari R; Jose J; Bhavnani V; Kumar N; Shastry P; Pal JK
Int J Biochem Cell Biol; 2016 Aug; 77(Pt A):57-67. PubMed ID: 27262235
[TBL] [Abstract][Full Text] [Related]
4. Dephosphorylation and inactivation of Akt/PKB is counteracted by protein kinase CK2 in HEK 293T cells.
Di Maira G; Brustolon F; Pinna LA; Ruzzene M
Cell Mol Life Sci; 2009 Oct; 66(20):3363-73. PubMed ID: 19662498
[TBL] [Abstract][Full Text] [Related]
5. Positive correlation between overexpression of phospho-BAD with phosphorylated Akt at serine 473 but not threonine 308 in colorectal carcinoma.
Khor TO; Gul YA; Ithnin H; Seow HF
Cancer Lett; 2004 Jul; 210(2):139-50. PubMed ID: 15183529
[TBL] [Abstract][Full Text] [Related]
6. Domain swapping used to investigate the mechanism of protein kinase B regulation by 3-phosphoinositide-dependent protein kinase 1 and Ser473 kinase.
Andjelković M; Maira SM; Cron P; Parker PJ; Hemmings BA
Mol Cell Biol; 1999 Jul; 19(7):5061-72. PubMed ID: 10373555
[TBL] [Abstract][Full Text] [Related]
7. Akt phosphorylation on Thr308 but not on Ser473 correlates with Akt protein kinase activity in human non-small cell lung cancer.
Vincent EE; Elder DJ; Thomas EC; Phillips L; Morgan C; Pawade J; Sohail M; May MT; Hetzel MR; Tavaré JM
Br J Cancer; 2011 May; 104(11):1755-61. PubMed ID: 21505451
[TBL] [Abstract][Full Text] [Related]
8. p28GANK inhibits endoplasmic reticulum stress-induced cell death via enhancement of the endoplasmic reticulum adaptive capacity.
Dai RY; Chen Y; Fu J; Dong LW; Ren YB; Yang GZ; Qian YW; Cao J; Tang SH; Yang SL; Wang HY
Cell Res; 2009 Nov; 19(11):1243-57. PubMed ID: 19736567
[TBL] [Abstract][Full Text] [Related]
9. PI3K/Akt promotes GRP78 accumulation and inhibits endoplasmic reticulum stress-induced apoptosis in HEK293 cells.
Dai RY; Chen SK; Yan DM; Chen R; Lui YP; Duan CY; Li J; He T; Li H
Folia Biol (Praha); 2010; 56(2):37-46. PubMed ID: 20492754
[TBL] [Abstract][Full Text] [Related]
10. Activated α2-macroglobulin binding to cell surface GRP78 induces T-loop phosphorylation of Akt1 by PDK1 in association with Raptor.
Misra UK; Pizzo SV
PLoS One; 2014; 9(2):e88373. PubMed ID: 24516643
[TBL] [Abstract][Full Text] [Related]
11. Regulation of Akt(ser473) phosphorylation by choline kinase in breast carcinoma cells.
Chua BT; Gallego-Ortega D; Ramirez de Molina A; Ullrich A; Lacal JC; Downward J
Mol Cancer; 2009 Dec; 8():131. PubMed ID: 20042122
[TBL] [Abstract][Full Text] [Related]
12. Akt phosphorylation at Thr308 and Ser473 is required for CHIP-mediated ubiquitination of the kinase.
Su CH; Wang CY; Lan KH; Li CP; Chao Y; Lin HC; Lee SD; Lee WP
Cell Signal; 2011 Nov; 23(11):1824-30. PubMed ID: 21767636
[TBL] [Abstract][Full Text] [Related]
13. Nerve growth factor protects the ischemic heart via attenuation of the endoplasmic reticulum stress induced apoptosis by activation of phosphatidylinositol 3-kinase.
Wei K; Liu L; Xie F; Hao X; Luo J; Min S
Int J Med Sci; 2015; 12(1):83-91. PubMed ID: 25552923
[TBL] [Abstract][Full Text] [Related]
14. The level of AKT phosphorylation on threonine 308 but not on serine 473 is associated with high-risk cytogenetics and predicts poor overall survival in acute myeloid leukaemia.
Gallay N; Dos Santos C; Cuzin L; Bousquet M; Simmonet Gouy V; Chaussade C; Attal M; Payrastre B; Demur C; Récher C
Leukemia; 2009 Jun; 23(6):1029-38. PubMed ID: 19158829
[TBL] [Abstract][Full Text] [Related]
15. Transcriptional regulation of the Grp78 promoter by endoplasmic reticulum stress: role of TFII-I and its tyrosine phosphorylation.
Hong M; Lin MY; Huang JM; Baumeister P; Hakre S; Roy AL; Lee AS
J Biol Chem; 2005 Apr; 280(17):16821-8. PubMed ID: 15664986
[TBL] [Abstract][Full Text] [Related]
16. Levels of PTEN protein modulate Akt phosphorylation on serine 473, but not on threonine 308, in IGF-II-overexpressing rhabdomyosarcomas cells.
Wan X; Helman LJ
Oncogene; 2003 Nov; 22(50):8205-11. PubMed ID: 14603261
[TBL] [Abstract][Full Text] [Related]
17. PDK1 acquires PDK2 activity in the presence of a synthetic peptide derived from the carboxyl terminus of PRK2.
Balendran A; Casamayor A; Deak M; Paterson A; Gaffney P; Currie R; Downes CP; Alessi DR
Curr Biol; 1999 Apr; 9(8):393-404. PubMed ID: 10226025
[TBL] [Abstract][Full Text] [Related]
18. PDK1 selectively phosphorylates Thr(308) on Akt and contributes to human platelet functional responses.
Dangelmaier C; Manne BK; Liverani E; Jin J; Bray P; Kunapuli SP
Thromb Haemost; 2014 Mar; 111(3):508-17. PubMed ID: 24352480
[TBL] [Abstract][Full Text] [Related]
19. Site-specific activation of AKT protects cells from death induced by glucose deprivation.
Gao M; Liang J; Lu Y; Guo H; German P; Bai S; Jonasch E; Yang X; Mills GB; Ding Z
Oncogene; 2014 Feb; 33(6):745-55. PubMed ID: 23396361
[TBL] [Abstract][Full Text] [Related]
20. Targeting the glucose-regulated protein-78 abrogates Pten-null driven AKT activation and endometrioid tumorigenesis.
Lin YG; Shen J; Yoo E; Liu R; Yen HY; Mehta A; Rajaei A; Yang W; Mhawech-Fauceglia P; DeMayo FJ; Lydon J; Gill P; Lee AS
Oncogene; 2015 Oct; 34(43):5418-26. PubMed ID: 25684138
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]