BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

127 related articles for article (PubMed ID: 21447610)

  • 1. Transgenic animal models in toxicology: historical perspectives and future outlook.
    Boverhof DR; Chamberlain MP; Elcombe CR; Gonzalez FJ; Heflich RH; Hernández LG; Jacobs AC; Jacobson-Kram D; Luijten M; Maggi A; Manjanatha MG; Benthem Jv; Gollapudi BB
    Toxicol Sci; 2011 Jun; 121(2):207-33. PubMed ID: 21447610
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The contribution of in vitro toxicity data in hazard and risk assessment: current limitations and future perspectives.
    Blaauboer BJ
    Toxicol Lett; 2008 Aug; 180(2):81-4. PubMed ID: 18586419
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Identification and hepatic expression profiles of cytochrome P450 1-4 isozymes in common minke whales (Balaenoptera acutorostrata).
    Niimi S; Kim EY; Iwata H; Watanabe MX; Yasunaga G; Fujise Y; Tanabe S
    Comp Biochem Physiol B Biochem Mol Biol; 2007 Aug; 147(4):667-81. PubMed ID: 17526421
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Toward the evaluation of function in genetic variability: characterizing human SNP frequencies and establishing BAC-transgenic mice carrying the human CYP1A1_CYP1A2 locus.
    Jiang Z; Dalton TP; Jin L; Wang B; Tsuneoka Y; Shertzer HG; Deka R; Nebert DW
    Hum Mutat; 2005 Feb; 25(2):196-206. PubMed ID: 15643613
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Safety assessment of drug metabolites: implications of regulatory guidance and potential application of genetically engineered mouse models that express human P450s.
    Powley MW; Frederick CB; Sistare FD; DeGeorge JJ
    Chem Res Toxicol; 2009 Feb; 22(2):257-62. PubMed ID: 19170595
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Toxicology in the 21st century--working our way towards a visionary reality.
    Berg N; De Wever B; Fuchs HW; Gaca M; Krul C; Roggen EL
    Toxicol In Vitro; 2011 Jun; 25(4):874-81. PubMed ID: 21338664
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Sequencing and characterization of mixed function monooxygenase genes CYP1A1 and CYP1A2 of Mink (Mustela vison) to facilitate study of dioxin-like compounds.
    Zhang X; Moore JN; Newsted JL; Hecker M; Zwiernik MJ; Jones PD; Bursian SJ; Giesy JP
    Toxicol Appl Pharmacol; 2009 Feb; 234(3):306-13. PubMed ID: 19041884
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Involvement of various molecular events in cellular injury induced by smokeless tobacco.
    Avti PK; Vaiphei K; Pathak CM; Khanduja KL
    Chem Res Toxicol; 2010 Jul; 23(7):1163-74. PubMed ID: 20521779
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Safety and nutritional assessment of GM plants and derived food and feed: the role of animal feeding trials.
    EFSA GMO Panel Working Group on Animal Feeding Trials
    Food Chem Toxicol; 2008 Mar; 46 Suppl 1():S2-70. PubMed ID: 18328408
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Naphthalene toxicity in mice and aryl hydrocarbon receptor-mediated CYPs.
    Genter MB; Marlowe J; Kevin Kerzee J; Dragin N; Puga A; Dalton TP; Nebert DW
    Biochem Biophys Res Commun; 2006 Sep; 348(1):120-3. PubMed ID: 16876762
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Modulation of acetaminophen-induced hepatotoxicity by the xenobiotic receptor CAR.
    Zhang J; Huang W; Chua SS; Wei P; Moore DD
    Science; 2002 Oct; 298(5592):422-4. PubMed ID: 12376703
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Molecular genetics of the human cytochrome P450 monooxygenase superfamily.
    Smith G; Stubbins MJ; Harries LW; Wolf CR
    Xenobiotica; 1998 Dec; 28(12):1129-65. PubMed ID: 9890157
    [No Abstract]   [Full Text] [Related]  

  • 13. Ontogeny of hepatic CYP1A2 and CYP2E1 expression in rat.
    Elbarbry FA; McNamara PJ; Alcorn J
    J Biochem Mol Toxicol; 2007; 21(1):41-50. PubMed ID: 17366540
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Transgenic rice plants expressing human p450 genes involved in xenobiotic metabolism for phytoremediation.
    Kawahigashi H; Hirose S; Ohkawa H; Ohkawa Y
    J Mol Microbiol Biotechnol; 2008; 15(2-3):212-9. PubMed ID: 18685273
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Transgenic rodents in toxicology.
    Dayan AD
    Int J Exp Pathol; 1996 Dec; 77(6):251-6. PubMed ID: 9155658
    [No Abstract]   [Full Text] [Related]  

  • 16. Inducibility of drug-metabolizing enzymes by xenobiotics in mice with liver-specific knockout of Ctnnb1.
    Braeuning A; Sanna R; Huelsken J; Schwarz M
    Drug Metab Dispos; 2009 May; 37(5):1138-45. PubMed ID: 19237511
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Toxicity testing in the 21st century: how will it affect risk assessment?
    Rhomberg LR
    J Toxicol Environ Health B Crit Rev; 2010 Feb; 13(2-4):361-75. PubMed ID: 20574908
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The future of toxicity testing.
    Andersen ME; Al-Zoughool M; Croteau M; Westphal M; Krewski D
    J Toxicol Environ Health B Crit Rev; 2010 Feb; 13(2-4):163-96. PubMed ID: 20574896
    [TBL] [Abstract][Full Text] [Related]  

  • 19. [Interindividual differences in efficacy and toxicity induced by therapeutic drugs and xenobiotics in relation to genetic polymorphisms in xenobiotic metabolizing enzymes].
    Ozawa S
    Kokuritsu Iyakuhin Shokuhin Eisei Kenkyusho Hokoku; 1998; (116):69-81. PubMed ID: 10097514
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Computational toxicology as implemented by the U.S. EPA: providing high throughput decision support tools for screening and assessing chemical exposure, hazard and risk.
    Kavlock R; Dix D
    J Toxicol Environ Health B Crit Rev; 2010 Feb; 13(2-4):197-217. PubMed ID: 20574897
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.