These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

228 related articles for article (PubMed ID: 21447642)

  • 1. Different residues in the GABAA receptor benzodiazepine binding pocket mediate benzodiazepine efficacy and binding.
    Morlock EV; Czajkowski C
    Mol Pharmacol; 2011 Jul; 80(1):14-22. PubMed ID: 21447642
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural mechanisms underlying benzodiazepine modulation of the GABA(A) receptor.
    Hanson SM; Czajkowski C
    J Neurosci; 2008 Mar; 28(13):3490-9. PubMed ID: 18367615
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Individually monitoring ligand-induced changes in the structure of the GABAA receptor at benzodiazepine binding site and non-binding-site interfaces.
    Sharkey LM; Czajkowski C
    Mol Pharmacol; 2008 Jul; 74(1):203-12. PubMed ID: 18424553
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification of transduction elements for benzodiazepine modulation of the GABA(A) receptor: three residues are required for allosteric coupling.
    Boileau AJ; Czajkowski C
    J Neurosci; 1999 Dec; 19(23):10213-20. PubMed ID: 10575018
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A (beta)-strand in the (gamma)2 subunit lines the benzodiazepine binding site of the GABA A receptor: structural rearrangements detected during channel gating.
    Teissére JA; Czajkowski C
    J Neurosci; 2001 Jul; 21(14):4977-86. PubMed ID: 11438573
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Allosteric modulators induce distinct movements at the GABA-binding site interface of the GABA-A receptor.
    Sancar F; Czajkowski C
    Neuropharmacology; 2011; 60(2-3):520-8. PubMed ID: 21093460
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural requirements for eszopiclone and zolpidem binding to the gamma-aminobutyric acid type-A (GABAA) receptor are different.
    Hanson SM; Morlock EV; Satyshur KA; Czajkowski C
    J Med Chem; 2008 Nov; 51(22):7243-52. PubMed ID: 18973287
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Molecular dissection of benzodiazepine binding and allosteric coupling using chimeric gamma-aminobutyric acidA receptor subunits.
    Boileau AJ; Kucken AM; Evers AR; Czajkowski C
    Mol Pharmacol; 1998 Feb; 53(2):295-303. PubMed ID: 9463488
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Two tyrosine residues on the alpha subunit are crucial for benzodiazepine binding and allosteric modulation of gamma-aminobutyric acidA receptors.
    Amin J; Brooks-Kayal A; Weiss DS
    Mol Pharmacol; 1997 May; 51(5):833-41. PubMed ID: 9145922
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Disulphide trapping of the GABA(A) receptor reveals the importance of the coupling interface in the action of benzodiazepines.
    Hanson SM; Czajkowski C
    Br J Pharmacol; 2011 Feb; 162(3):673-87. PubMed ID: 20942818
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural elements of the gamma-aminobutyric acid type A receptor conferring subtype selectivity for benzodiazepine site ligands.
    Renard S; Olivier A; Granger P; Avenet P; Graham D; Sevrin M; George P; Besnard F
    J Biol Chem; 1999 May; 274(19):13370-4. PubMed ID: 10224099
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A point mutation in the gamma2 subunit of gamma-aminobutyric acid type A receptors results in altered benzodiazepine binding site specificity.
    Buhr A; Sigel E
    Proc Natl Acad Sci U S A; 1997 Aug; 94(16):8824-9. PubMed ID: 9238062
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structural requirements for imidazobenzodiazepine binding to GABA(A) receptors.
    Kucken AM; Teissére JA; Seffinga-Clark J; Wagner DA; Czajkowski C
    Mol Pharmacol; 2003 Feb; 63(2):289-96. PubMed ID: 12527800
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification of benzodiazepine binding site residues in the gamma2 subunit of the gamma-aminobutyric acid(A) receptor.
    Kucken AM; Wagner DA; Ward PR; Teissére JA; Boileau AJ; Czajkowski C
    Mol Pharmacol; 2000 May; 57(5):932-9. PubMed ID: 10779376
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Alterations of the benzodiazepine site of rat alpha 6 beta 2 gamma 2-GABAA receptor by replacement of several divergent amino-terminal regions with the alpha 1 counterparts.
    Im WB; Pregenzer JF; Binder JA; Alberts GL; Im HK
    Br J Pharmacol; 1997 Feb; 120(4):559-64. PubMed ID: 9051290
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Residues at positions 206 and 209 of the alpha1 subunit of gamma-aminobutyric AcidA receptors influence affinities for benzodiazepine binding site ligands.
    Buhr A; Schaerer MT; Baur R; Sigel E
    Mol Pharmacol; 1997 Oct; 52(4):676-82. PubMed ID: 9380031
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Heterogeneity in the allosteric interaction between the gamma-aminobutyric acid (GABA) binding site and three different benzodiazepine binding sites of the GABAA/benzodiazepine receptor complex in the rat nervous system.
    Ruano D; Vizuete M; Cano J; Machado A; Vitorica J
    J Neurochem; 1992 Feb; 58(2):485-93. PubMed ID: 1309562
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification of amino acid residues responsible for the alpha5 subunit binding selectivity of L-655,708, a benzodiazepine binding site ligand at the GABA(A) receptor.
    Casula MA; Bromidge FA; Pillai GV; Wingrove PB; Martin K; Maubach K; Seabrook GR; Whiting PJ; Hadingham KL
    J Neurochem; 2001 Apr; 77(2):445-51. PubMed ID: 11299307
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The F-loop of the GABA A receptor gamma2 subunit contributes to benzodiazepine modulation.
    Padgett CL; Lummis SC
    J Biol Chem; 2008 Feb; 283(5):2702-8. PubMed ID: 17974564
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Subtle changes in residue 77 of the gamma subunit of alpha1beta2gamma2 GABAA receptors drastically alter the affinity for ligands of the benzodiazepine binding site.
    Buhr A; Baur R; Sigel E
    J Biol Chem; 1997 May; 272(18):11799-804. PubMed ID: 9115236
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.