BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

268 related articles for article (PubMed ID: 21454529)

  • 1. Uracil-DNA glycosylase in base excision repair and adaptive immunity: species differences between man and mouse.
    Doseth B; Visnes T; Wallenius A; Ericsson I; Sarno A; Pettersen HS; Flatberg A; Catterall T; Slupphaug G; Krokan HE; Kavli B
    J Biol Chem; 2011 May; 286(19):16669-80. PubMed ID: 21454529
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Germline ablation of SMUG1 DNA glycosylase causes loss of 5-hydroxymethyluracil- and UNG-backup uracil-excision activities and increases cancer predisposition of Ung-/-Msh2-/- mice.
    Kemmerich K; Dingler FA; Rada C; Neuberger MS
    Nucleic Acids Res; 2012 Jul; 40(13):6016-25. PubMed ID: 22447450
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Uracil in DNA--general mutagen, but normal intermediate in acquired immunity.
    Kavli B; Otterlei M; Slupphaug G; Krokan HE
    DNA Repair (Amst); 2007 Apr; 6(4):505-16. PubMed ID: 17116429
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Strikingly different properties of uracil-DNA glycosylases UNG2 and SMUG1 may explain divergent roles in processing of genomic uracil.
    Doseth B; Ekre C; Slupphaug G; Krokan HE; Kavli B
    DNA Repair (Amst); 2012 Jun; 11(6):587-93. PubMed ID: 22483865
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Uracil excision by endogenous SMUG1 glycosylase promotes efficient Ig class switching and impacts on A:T substitutions during somatic mutation.
    Dingler FA; Kemmerich K; Neuberger MS; Rada C
    Eur J Immunol; 2014 Jul; 44(7):1925-35. PubMed ID: 24771041
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Nucleosomes and the three glycosylases: High, medium, and low levels of excision by the uracil DNA glycosylase superfamily.
    Tarantino ME; Dow BJ; Drohat AC; Delaney S
    DNA Repair (Amst); 2018 Dec; 72():56-63. PubMed ID: 30268365
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Refining the Neuberger model: Uracil processing by activated B cells.
    Maul RW; Gearhart PJ
    Eur J Immunol; 2014 Jul; 44(7):1913-6. PubMed ID: 24920531
    [TBL] [Abstract][Full Text] [Related]  

  • 8. B cells from hyper-IgM patients carrying UNG mutations lack ability to remove uracil from ssDNA and have elevated genomic uracil.
    Kavli B; Andersen S; Otterlei M; Liabakk NB; Imai K; Fischer A; Durandy A; Krokan HE; Slupphaug G
    J Exp Med; 2005 Jun; 201(12):2011-21. PubMed ID: 15967827
    [TBL] [Abstract][Full Text] [Related]  

  • 9. RPA guides UNG to uracil in ssDNA to facilitate antibody class switching and repair of mutagenic uracil at the replication fork.
    Hayran AB; Liabakk NB; Aas PA; Kusnierczyk A; Vågbø CB; Sarno A; Iveland TS; Chawla K; Zahn A; Di Noia JM; Slupphaug G; Kavli B
    Nucleic Acids Res; 2024 Jan; 52(2):784-800. PubMed ID: 38000394
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Uracil in DNA--occurrence, consequences and repair.
    Krokan HE; Drabløs F; Slupphaug G
    Oncogene; 2002 Dec; 21(58):8935-48. PubMed ID: 12483510
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Uracil Accumulation and Mutagenesis Dominated by Cytosine Deamination in CpG Dinucleotides in Mice Lacking UNG and SMUG1.
    Alsøe L; Sarno A; Carracedo S; Domanska D; Dingler F; Lirussi L; SenGupta T; Tekin NB; Jobert L; Alexandrov LB; Galashevskaya A; Rada C; Sandve GK; Rognes T; Krokan HE; Nilsen H
    Sci Rep; 2017 Aug; 7(1):7199. PubMed ID: 28775312
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Further evidence for involvement of a noncanonical function of uracil DNA glycosylase in class switch recombination.
    Begum NA; Stanlie A; Doi T; Sasaki Y; Jin HW; Kim YS; Nagaoka H; Honjo T
    Proc Natl Acad Sci U S A; 2009 Feb; 106(8):2752-7. PubMed ID: 19202054
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Uracil-DNA glycosylase UNG1 isoform variant supports class switch recombination and repairs nuclear genomic uracil.
    Sarno A; Lundbæk M; Liabakk NB; Aas PA; Mjelle R; Hagen L; Sousa MML; Krokan HE; Kavli B
    Nucleic Acids Res; 2019 May; 47(9):4569-4585. PubMed ID: 30838409
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Uracil-DNA glycosylases SMUG1 and UNG2 coordinate the initial steps of base excision repair by distinct mechanisms.
    Pettersen HS; Sundheim O; Gilljam KM; Slupphaug G; Krokan HE; Kavli B
    Nucleic Acids Res; 2007; 35(12):3879-92. PubMed ID: 17537817
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Excision of deaminated cytosine from the vertebrate genome: role of the SMUG1 uracil-DNA glycosylase.
    Nilsen H; Haushalter KA; Robins P; Barnes DE; Verdine GL; Lindahl T
    EMBO J; 2001 Aug; 20(15):4278-86. PubMed ID: 11483530
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Insights from xanthine and uracil DNA glycosylase activities of bacterial and human SMUG1: switching SMUG1 to UDG.
    Mi R; Dong L; Kaulgud T; Hackett KW; Dominy BN; Cao W
    J Mol Biol; 2009 Jan; 385(3):761-78. PubMed ID: 18835277
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dependence of antibody gene diversification on uracil excision.
    Di Noia JM; Williams GT; Chan DT; Buerstedde JM; Baldwin GS; Neuberger MS
    J Exp Med; 2007 Dec; 204(13):3209-19. PubMed ID: 18070939
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Repair of APOBEC3G-Mutated Retroviral DNA
    Salas-Briceno K; Ross SR
    J Virol; 2021 Oct; 95(22):e0124421. PubMed ID: 34468176
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structure and specificity of the vertebrate anti-mutator uracil-DNA glycosylase SMUG1.
    Wibley JE; Waters TR; Haushalter K; Verdine GL; Pearl LH
    Mol Cell; 2003 Jun; 11(6):1647-59. PubMed ID: 12820976
    [TBL] [Abstract][Full Text] [Related]  

  • 20. SMUG1 is able to excise uracil from immunoglobulin genes: insight into mutation versus repair.
    Di Noia JM; Rada C; Neuberger MS
    EMBO J; 2006 Feb; 25(3):585-95. PubMed ID: 16407970
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.