239 related articles for article (PubMed ID: 21454562)
1. Refinement of glucagon-like peptide 1 docking to its intact receptor using mid-region photolabile probes and molecular modeling.
Miller LJ; Chen Q; Lam PC; Pinon DI; Sexton PM; Abagyan R; Dong M
J Biol Chem; 2011 May; 286(18):15895-907. PubMed ID: 21454562
[TBL] [Abstract][Full Text] [Related]
2. Spatial approximations between residues 6 and 12 in the amino-terminal region of glucagon-like peptide 1 and its receptor: a region critical for biological activity.
Chen Q; Pinon DI; Miller LJ; Dong M
J Biol Chem; 2010 Aug; 285(32):24508-18. PubMed ID: 20529866
[TBL] [Abstract][Full Text] [Related]
3. Molecular basis of glucagon-like peptide 1 docking to its intact receptor studied with carboxyl-terminal photolabile probes.
Chen Q; Pinon DI; Miller LJ; Dong M
J Biol Chem; 2009 Dec; 284(49):34135-44. PubMed ID: 19815559
[TBL] [Abstract][Full Text] [Related]
4. Molecular basis of secretin docking to its intact receptor using multiple photolabile probes distributed throughout the pharmacophore.
Dong M; Lam PC; Pinon DI; Hosohata K; Orry A; Sexton PM; Abagyan R; Miller LJ
J Biol Chem; 2011 Jul; 286(27):23888-99. PubMed ID: 21566140
[TBL] [Abstract][Full Text] [Related]
5. Second extracellular loop of human glucagon-like peptide-1 receptor (GLP-1R) has a critical role in GLP-1 peptide binding and receptor activation.
Koole C; Wootten D; Simms J; Miller LJ; Christopoulos A; Sexton PM
J Biol Chem; 2012 Feb; 287(6):3642-58. PubMed ID: 22147710
[TBL] [Abstract][Full Text] [Related]
6. Site of action of a pentapeptide agonist at the glucagon-like peptide-1 receptor. Insight into a small molecule agonist-binding pocket.
Dong M; Pinon DI; Miller LJ
Bioorg Med Chem Lett; 2012 Jan; 22(1):638-41. PubMed ID: 22079758
[TBL] [Abstract][Full Text] [Related]
7. Insights into the structural basis of endogenous agonist activation of family B G protein-coupled receptors.
Dong M; Gao F; Pinon DI; Miller LJ
Mol Endocrinol; 2008 Jun; 22(6):1489-99. PubMed ID: 18372345
[TBL] [Abstract][Full Text] [Related]
8. Residues within the transmembrane domain of the glucagon-like peptide-1 receptor involved in ligand binding and receptor activation: modelling the ligand-bound receptor.
Coopman K; Wallis R; Robb G; Brown AJ; Wilkinson GF; Timms D; Willars GB
Mol Endocrinol; 2011 Oct; 25(10):1804-18. PubMed ID: 21868452
[TBL] [Abstract][Full Text] [Related]
9. Spatial approximation between the amino terminus of a peptide agonist and the top of the sixth transmembrane segment of the secretin receptor.
Dong M; Li Z; Pinon DI; Lybrand TP; Miller LJ
J Biol Chem; 2004 Jan; 279(4):2894-903. PubMed ID: 14593094
[TBL] [Abstract][Full Text] [Related]
10. Molecular approximations between residues 21 and 23 of secretin and its receptor: development of a model for peptide docking with the amino terminus of the secretin receptor.
Dong M; Lam PC; Gao F; Hosohata K; Pinon DI; Sexton PM; Abagyan R; Miller LJ
Mol Pharmacol; 2007 Aug; 72(2):280-90. PubMed ID: 17475809
[TBL] [Abstract][Full Text] [Related]
11. Differential spatial approximation between secretin and its receptor residues in active and inactive conformations demonstrated by photoaffinity labeling.
Dong M; Hosohata K; Pinon DI; Muthukumaraswamy N; Miller LJ
Mol Endocrinol; 2006 Jul; 20(7):1688-98. PubMed ID: 16513792
[TBL] [Abstract][Full Text] [Related]
12. Crystal structure of glucagon-like peptide-1 in complex with the extracellular domain of the glucagon-like peptide-1 receptor.
Underwood CR; Garibay P; Knudsen LB; Hastrup S; Peters GH; Rudolph R; Reedtz-Runge S
J Biol Chem; 2010 Jan; 285(1):723-30. PubMed ID: 19861722
[TBL] [Abstract][Full Text] [Related]
13. Evolutionarily conserved residues at glucagon-like peptide-1 (GLP-1) receptor core confer ligand-induced receptor activation.
Moon MJ; Kim HY; Park S; Kim DK; Cho EB; Park CR; You DJ; Hwang JI; Kim K; Choe H; Seong JY
J Biol Chem; 2012 Feb; 287(6):3873-84. PubMed ID: 22105074
[TBL] [Abstract][Full Text] [Related]
14. Ligand binding pocket formed by evolutionarily conserved residues in the glucagon-like peptide-1 (GLP-1) receptor core domain.
Moon MJ; Lee YN; Park S; Reyes-Alcaraz A; Hwang JI; Millar RP; Choe H; Seong JY
J Biol Chem; 2015 Feb; 290(9):5696-706. PubMed ID: 25561730
[TBL] [Abstract][Full Text] [Related]
15. Characterization of [¹²⁵I]GLP-1(9-36), a novel radiolabeled analog of the major metabolite of glucagon-like peptide 1 to a receptor distinct from GLP1-R and function of the peptide in murine aorta.
Kuc RE; Maguire JJ; Siew K; Patel S; Derksen DR; Margaret Jackson V; O'Shaughnessey KM; Davenport AP
Life Sci; 2014 May; 102(2):134-8. PubMed ID: 24641952
[TBL] [Abstract][Full Text] [Related]
16. Differential docking of high-affinity peptide ligands to type A and B cholecystokinin receptors demonstrated by photoaffinity labeling.
Dong M; Liu G; Pinon DI; Miller LJ
Biochemistry; 2005 May; 44(17):6693-700. PubMed ID: 15850403
[TBL] [Abstract][Full Text] [Related]
17. Importance of the amino terminus in secretin family G protein-coupled receptors. Intrinsic photoaffinity labeling establishes initial docking constraints for the calcitonin receptor.
Dong M; Pinon DI; Cox RF; Miller LJ
J Biol Chem; 2004 Jan; 279(2):1167-75. PubMed ID: 14583624
[TBL] [Abstract][Full Text] [Related]
18. Structural Determinants of Binding the Seven-transmembrane Domain of the Glucagon-like Peptide-1 Receptor (GLP-1R).
Yang D; de Graaf C; Yang L; Song G; Dai A; Cai X; Feng Y; Reedtz-Runge S; Hanson MA; Yang H; Jiang H; Stevens RC; Wang MW
J Biol Chem; 2016 Jun; 291(25):12991-3004. PubMed ID: 27059958
[TBL] [Abstract][Full Text] [Related]
19. Elucidation of the molecular basis of cholecystokinin Peptide docking to its receptor using site-specific intrinsic photoaffinity labeling and molecular modeling.
Dong M; Lam PC; Pinon DI; Abagyan R; Miller LJ
Biochemistry; 2009 Jun; 48(23):5303-12. PubMed ID: 19441839
[TBL] [Abstract][Full Text] [Related]
20. Identification of two pairs of spatially approximated residues within the carboxyl terminus of secretin and its receptor.
Dong M; Asmann YW; Zang M; Pinon DI; Miller LJ
J Biol Chem; 2000 Aug; 275(34):26032-9. PubMed ID: 10859300
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]