BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

478 related articles for article (PubMed ID: 21454652)

  • 1. SEL1L protein critically determines the stability of the HRD1-SEL1L endoplasmic reticulum-associated degradation (ERAD) complex to optimize the degradation kinetics of ERAD substrates.
    Iida Y; Fujimori T; Okawa K; Nagata K; Wada I; Hosokawa N
    J Biol Chem; 2011 May; 286(19):16929-39. PubMed ID: 21454652
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Association of the SEL1L protein transmembrane domain with HRD1 ubiquitin ligase regulates ERAD-L.
    Hosokawa N; Wada I
    FEBS J; 2016 Jan; 283(1):157-72. PubMed ID: 26471130
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Role of HERP and a HERP-related protein in HRD1-dependent protein degradation at the endoplasmic reticulum.
    Huang CH; Chu YR; Ye Y; Chen X
    J Biol Chem; 2014 Feb; 289(7):4444-54. PubMed ID: 24366871
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Human XTP3-B forms an endoplasmic reticulum quality control scaffold with the HRD1-SEL1L ubiquitin ligase complex and BiP.
    Hosokawa N; Wada I; Nagasawa K; Moriyama T; Okawa K; Nagata K
    J Biol Chem; 2008 Jul; 283(30):20914-24. PubMed ID: 18502753
    [TBL] [Abstract][Full Text] [Related]  

  • 5. SEL1L is required for endoplasmic reticulum-associated degradation of misfolded luminal proteins but not transmembrane proteins in chicken DT40 cell line.
    Ninagawa S; Okada T; Takeda S; Mori K
    Cell Struct Funct; 2011; 36(2):187-95. PubMed ID: 21857145
    [TBL] [Abstract][Full Text] [Related]  

  • 6. OS-9 and GRP94 deliver mutant alpha1-antitrypsin to the Hrd1-SEL1L ubiquitin ligase complex for ERAD.
    Christianson JC; Shaler TA; Tyler RE; Kopito RR
    Nat Cell Biol; 2008 Mar; 10(3):272-82. PubMed ID: 18264092
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Endoplasmic reticulum lectin XTP3-B inhibits endoplasmic reticulum-associated degradation of a misfolded α1-antitrypsin variant.
    Fujimori T; Kamiya Y; Nagata K; Kato K; Hosokawa N
    FEBS J; 2013 Mar; 280(6):1563-75. PubMed ID: 23356641
    [TBL] [Abstract][Full Text] [Related]  

  • 8. gp78 functions downstream of Hrd1 to promote degradation of misfolded proteins of the endoplasmic reticulum.
    Zhang T; Xu Y; Liu Y; Ye Y
    Mol Biol Cell; 2015 Dec; 26(24):4438-50. PubMed ID: 26424800
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Herp regulates Hrd1-mediated ubiquitylation in a ubiquitin-like domain-dependent manner.
    Kny M; Standera S; Hartmann-Petersen R; Kloetzel PM; Seeger M
    J Biol Chem; 2011 Feb; 286(7):5151-6. PubMed ID: 21149444
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of ERAD components essential for dislocation of the null Hong Kong variant of α-1-antitrypsin (NHK).
    Zhong Y; Shen H; Wang Y; Yang Y; Yang P; Fang S
    Biochem Biophys Res Commun; 2015 Mar; 458(2):424-8. PubMed ID: 25660456
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Derlin2 protein facilitates HRD1-mediated retro-translocation of sonic hedgehog at the endoplasmic reticulum.
    Huang CH; Hsiao HT; Chu YR; Ye Y; Chen X
    J Biol Chem; 2013 Aug; 288(35):25330-25339. PubMed ID: 23867461
    [TBL] [Abstract][Full Text] [Related]  

  • 12. SEL1L-dependent Substrates Require Derlin2/3 and Herp1/2 for Endoplasmic Reticulum-associated Degradation.
    Sugimoto T; Ninagawa S; Yamano S; Ishikawa T; Okada T; Takeda S; Mori K
    Cell Struct Funct; 2017 Jul; 42(2):81-94. PubMed ID: 28552883
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The ubiquitin-domain protein HERP forms a complex with components of the endoplasmic reticulum associated degradation pathway.
    Schulze A; Standera S; Buerger E; Kikkert M; van Voorden S; Wiertz E; Koning F; Kloetzel PM; Seeger M
    J Mol Biol; 2005 Dec; 354(5):1021-7. PubMed ID: 16289116
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The unfolded protein response transducer ATF6 represents a novel transmembrane-type endoplasmic reticulum-associated degradation substrate requiring both mannose trimming and SEL1L protein.
    Horimoto S; Ninagawa S; Okada T; Koba H; Sugimoto T; Kamiya Y; Kato K; Takeda S; Mori K
    J Biol Chem; 2013 Nov; 288(44):31517-27. PubMed ID: 24043630
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Different p97/VCP complexes function in retrotranslocation step of mammalian ER-associated degradation (ERAD).
    Ballar P; Pabuccuoglu A; Kose FA
    Int J Biochem Cell Biol; 2011 Apr; 43(4):613-21. PubMed ID: 21199683
    [TBL] [Abstract][Full Text] [Related]  

  • 16. SEL1L-HRD1 interaction is required to form a functional HRD1 ERAD complex.
    Lin LL; Wang HH; Pederson B; Wei X; Torres M; Lu Y; Li ZJ; Liu X; Mao H; Wang H; Zhou LE; Zhao Z; Sun S; Qi L
    Nat Commun; 2024 Feb; 15(1):1440. PubMed ID: 38365914
    [TBL] [Abstract][Full Text] [Related]  

  • 17. USP19-Mediated Deubiquitination Facilitates the Stabilization of HRD1 Ubiquitin Ligase.
    Harada K; Kato M; Nakamura N
    Int J Mol Sci; 2016 Nov; 17(11):. PubMed ID: 27827840
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Sel1L is indispensable for mammalian endoplasmic reticulum-associated degradation, endoplasmic reticulum homeostasis, and survival.
    Sun S; Shi G; Han X; Francisco AB; Ji Y; Mendonça N; Liu X; Locasale JW; Simpson KW; Duhamel GE; Kersten S; Yates JR; Long Q; Qi L
    Proc Natl Acad Sci U S A; 2014 Feb; 111(5):E582-91. PubMed ID: 24453213
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Human Cytomegalovirus Tropism Modulator UL148 Interacts with SEL1L, a Cellular Factor That Governs Endoplasmic Reticulum-Associated Degradation of the Viral Envelope Glycoprotein gO.
    Nguyen CC; Siddiquey MNA; Zhang H; Li G; Kamil JP
    J Virol; 2018 Sep; 92(18):. PubMed ID: 29997207
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The Dfm1 Derlin Is Required for ERAD Retrotranslocation of Integral Membrane Proteins.
    Neal S; Jaeger PA; Duttke SH; Benner C; K Glass C; Ideker T; Hampton RY
    Mol Cell; 2018 Jan; 69(2):306-320.e4. PubMed ID: 29351849
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 24.