BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

298 related articles for article (PubMed ID: 21454676)

  • 1. Down-regulation of cytokine-induced interleukin-8 requires inhibition of p38 mitogen-activated protein kinase (MAPK) via MAPK phosphatase 1-dependent and -independent mechanisms.
    Dauletbaev N; Eklove D; Mawji N; Iskandar M; Di Marco S; Gallouzi IE; Lands LC
    J Biol Chem; 2011 May; 286(18):15998-6007. PubMed ID: 21454676
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of NF-kappaB-dependent transcription by MKP-1: transcriptional repression by glucocorticoids occurring via p38 MAPK.
    King EM; Holden NS; Gong W; Rider CF; Newton R
    J Biol Chem; 2009 Sep; 284(39):26803-15. PubMed ID: 19648110
    [TBL] [Abstract][Full Text] [Related]  

  • 3. MKP-1: a negative feedback effector that represses MAPK-mediated pro-inflammatory signaling pathways and cytokine secretion in human airway smooth muscle cells.
    Manetsch M; Che W; Seidel P; Chen Y; Ammit AJ
    Cell Signal; 2012 Apr; 24(4):907-13. PubMed ID: 22200679
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mitogen-activated protein kinase phosphatase-1 negatively regulates the expression of interleukin-6, interleukin-8, and cyclooxygenase-2 in A549 human lung epithelial cells.
    Turpeinen T; Nieminen R; Moilanen E; Korhonen R
    J Pharmacol Exp Ther; 2010 Apr; 333(1):310-8. PubMed ID: 20089808
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Aurothiomalate inhibits cyclooxygenase 2, matrix metalloproteinase 3, and interleukin-6 expression in chondrocytes by increasing MAPK phosphatase 1 expression and decreasing p38 phosphorylation: MAPK phosphatase 1 as a novel target for antirheumatic drugs.
    Nieminen R; Korhonen R; Moilanen T; Clark AR; Moilanen E
    Arthritis Rheum; 2010 Jun; 62(6):1650-9. PubMed ID: 20178133
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Corticosteroids reduce IL-6 in ASM cells via up-regulation of MKP-1.
    Quante T; Ng YC; Ramsay EE; Henness S; Allen JC; Parmentier J; Ge Q; Ammit AJ
    Am J Respir Cell Mol Biol; 2008 Aug; 39(2):208-17. PubMed ID: 18314542
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Dexamethasone causes sustained expression of mitogen-activated protein kinase (MAPK) phosphatase 1 and phosphatase-mediated inhibition of MAPK p38.
    Lasa M; Abraham SM; Boucheron C; Saklatvala J; Clark AR
    Mol Cell Biol; 2002 Nov; 22(22):7802-11. PubMed ID: 12391149
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Suppression of cytokine production by glucocorticoids is mediated by MKP-1 in human lung epithelial cells.
    Keränen T; Moilanen E; Korhonen R
    Inflamm Res; 2017 May; 66(5):441-449. PubMed ID: 28299397
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Dexamethasone suppresses interleukin-1beta-induced human beta-defensin 2 mRNA expression: involvement of p38 MAPK, JNK, MKP-1, and NF-kappaB transcriptional factor in A549 cells.
    Jang BC; Lim KJ; Suh MH; Park JG; Suh SI
    FEMS Immunol Med Microbiol; 2007 Oct; 51(1):171-84. PubMed ID: 17645739
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Temporal regulation of cytokine mRNA expression by tristetraprolin: dynamic control by p38 MAPK and MKP-1.
    Prabhala P; Bunge K; Rahman MM; Ge Q; Clark AR; Ammit AJ
    Am J Physiol Lung Cell Mol Physiol; 2015 May; 308(9):L973-80. PubMed ID: 25724669
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Annexin 1 negatively regulates IL-6 expression via effects on p38 MAPK and MAPK phosphatase-1.
    Yang YH; Toh ML; Clyne CD; Leech M; Aeberli D; Xue J; Dacumos A; Sharma L; Morand EF
    J Immunol; 2006 Dec; 177(11):8148-53. PubMed ID: 17114490
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Corticosteroid inhibition of growth-related oncogene protein-alpha via mitogen-activated kinase phosphatase-1 in airway smooth muscle cells.
    Issa R; Xie S; Khorasani N; Sukkar M; Adcock IM; Lee KY; Chung KF
    J Immunol; 2007 Jun; 178(11):7366-75. PubMed ID: 17513787
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Interleukin-17A stimulates cardiac fibroblast proliferation and migration via negative regulation of the dual-specificity phosphatase MKP-1/DUSP-1.
    Valente AJ; Yoshida T; Gardner JD; Somanna N; Delafontaine P; Chandrasekar B
    Cell Signal; 2012 Feb; 24(2):560-568. PubMed ID: 22037550
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ibuprofen modulates NF-kB activity but not IL-8 production in cystic fibrosis respiratory epithelial cells.
    Dauletbaev N; Lam J; Eklove D; Iskandar M; Lands LC
    Respiration; 2010; 79(3):234-42. PubMed ID: 19887769
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Expression of mitogen-activated protein kinase phosphatase 1, a negative regulator of the mitogen-activated protein kinases, in rheumatoid arthritis: up-regulation by interleukin-1beta and glucocorticoids.
    Toh ML; Yang Y; Leech M; Santos L; Morand EF
    Arthritis Rheum; 2004 Oct; 50(10):3118-28. PubMed ID: 15476200
    [TBL] [Abstract][Full Text] [Related]  

  • 16. ANP inhibits TNF-alpha-induced endothelial MCP-1 expression--involvement of p38 MAPK and MKP-1.
    Weber NC; Blumenthal SB; Hartung T; Vollmar AM; Kiemer AK
    J Leukoc Biol; 2003 Nov; 74(5):932-41. PubMed ID: 12960255
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Strong inhibition of TNF-alpha production and inhibition of IL-8 and COX-2 mRNA expression in monocyte-derived macrophages by RWJ 67657, a p38 mitogen-activated protein kinase (MAPK) inhibitor.
    Westra J; Doornbos-van der Meer B; de Boer P; van Leeuwen MA; van Rijswijk MH; Limburg PC
    Arthritis Res Ther; 2004; 6(4):R384-92. PubMed ID: 15225374
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Corticosteroid-Induced MKP-1 Represses Pro-Inflammatory Cytokine Secretion by Enhancing Activity of Tristetraprolin (TTP) in ASM Cells.
    Prabhala P; Bunge K; Ge Q; Ammit AJ
    J Cell Physiol; 2016 Oct; 231(10):2153-8. PubMed ID: 26825339
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Novel p38 MAPK inhibitor ML3403 has potent anti-inflammatory activity in airway smooth muscle.
    Munoz L; Ramsay EE; Manetsch M; Ge Q; Peifer C; Laufer S; Ammit AJ
    Eur J Pharmacol; 2010 Jun; 635(1-3):212-8. PubMed ID: 20226180
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Regulation of tristetraprolin expression by mitogen-activated protein kinase phosphatase-1.
    Huotari N; Hömmö T; Taimi V; Nieminen R; Moilanen E; Korhonen R
    APMIS; 2012 Dec; 120(12):988-99. PubMed ID: 23030431
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.