These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

87 related articles for article (PubMed ID: 21455979)

  • 1. Synthesis and in vitro characterization of drug conjugates of l-carnitine as potential prodrugs that target human Octn2.
    Diao L; Polli JE
    J Pharm Sci; 2011 Sep; 100(9):3802-16. PubMed ID: 21455979
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis, transport and mechanism of a type I prodrug: L-carnitine ester of prednisolone.
    Mo JX; Shi SJ; Zhang Q; Gong T; Sun X; Zhang ZR
    Mol Pharm; 2011 Oct; 8(5):1629-40. PubMed ID: 21854030
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Transport of butyryl-L-carnitine, a potential prodrug, via the carnitine transporter OCTN2 and the amino acid transporter ATB(0,+).
    Srinivas SR; Prasad PD; Umapathy NS; Ganapathy V; Shekhawat PS
    Am J Physiol Gastrointest Liver Physiol; 2007 Nov; 293(5):G1046-53. PubMed ID: 17855766
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Na(+)-dependent carnitine transport by organic cation transporter (OCTN2): its pharmacological and toxicological relevance.
    Ohashi R; Tamai I; Yabuuchi H; Nezu JI; Oku A; Sai Y; Shimane M; Tsuji A
    J Pharmacol Exp Ther; 1999 Nov; 291(2):778-84. PubMed ID: 10525100
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Interaction between pivaloylcarnitine and L-carnitine transport into L6 cells overexpressing hOCTN2.
    Todesco L; Bodmer M; Vonwil K; Häussinger D; Krähenbühl S
    Chem Biol Interact; 2009 Aug; 180(3):472-7. PubMed ID: 19539806
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and in vitro evaluation of gabapentin prodrugs that target the human apical sodium-dependent bile acid transporter (hASBT).
    Rais R; Fletcher S; Polli JE
    J Pharm Sci; 2011 Mar; 100(3):1184-95. PubMed ID: 20848648
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Role of Na+/L-carnitine transporter (OCTN2) in renal handling of pivaloylcarnitine and valproylcarnitine formed during pivalic acid-containing prodrugs and valproic acid treatment.
    Ohnishi S; Okamura N; Sakamoto S; Hasegawa H; Norikura R; Kanaoka E; Takahashi K; Horie K; Sakamoto K; Baba T
    Drug Metab Pharmacokinet; 2008; 23(4):293-303. PubMed ID: 18762717
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and in vitro evaluation of potential sustained release prodrugs via targeting ASBT.
    Zheng X; Polli JE
    Int J Pharm; 2010 Aug; 396(1-2):111-8. PubMed ID: 20600720
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Studies on functional sites of organic cation/carnitine transporter OCTN2 (SLC22A5) using a Ser467Cys mutant protein.
    Ohashi R; Tamai I; Inano A; Katsura M; Sai Y; Nezu J; Tsuji A
    J Pharmacol Exp Ther; 2002 Sep; 302(3):1286-94. PubMed ID: 12183691
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Recent advances in drug delivery via the organic cation/carnitine transporter 2 (OCTN2/SLC22A5).
    Kou L; Sun R; Ganapathy V; Yao Q; Chen R
    Expert Opin Ther Targets; 2018 Aug; 22(8):715-726. PubMed ID: 30016594
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Functional expression of the organic cation/carnitine transporter 2 in rat astrocytes.
    Inazu M; Takeda H; Maehara K; Miyashita K; Tomoda A; Matsumiya T
    J Neurochem; 2006 Apr; 97(2):424-34. PubMed ID: 16539668
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Expression and localization of organic cation/carnitine transporter OCTN2 in Caco-2 cells.
    Elimrani I; Lahjouji K; Seidman E; Roy MJ; Mitchell GA; Qureshi I
    Am J Physiol Gastrointest Liver Physiol; 2003 May; 284(5):G863-71. PubMed ID: 12684216
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Species specificity profiling of rat and human organic cation/carnitine transporter Slc22a5/SLC22A5 (Octn2/OCTN2).
    Szabó K; Nagy Z; Juhász V; Zolnerciks JK; Csorba A; Tímár Z; Molnár É; Pádár P; Johnson W; Beéry E; Krajcsi P
    Drug Metab Pharmacokinet; 2017 Jun; 32(3):165-171. PubMed ID: 28365301
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Selective inhibition of OCTN2 is more effective than inhibition of gamma-butyrobetaine dioxygenase to decrease the availability of l-carnitine and to reduce myocardial infarct size.
    Liepinsh E; Makrecka M; Kuka J; Cirule H; Makarova E; Sevostjanovs E; Grinberga S; Vilskersts R; Lola D; Loza E; Stonans I; Pugovics O; Dambrova M
    Pharmacol Res; 2014 Jul; 85():33-8. PubMed ID: 24836867
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Oxaliplatin transport mediated by organic cation/carnitine transporters OCTN1 and OCTN2 in overexpressing human embryonic kidney 293 cells and rat dorsal root ganglion neurons.
    Jong NN; Nakanishi T; Liu JJ; Tamai I; McKeage MJ
    J Pharmacol Exp Ther; 2011 Aug; 338(2):537-47. PubMed ID: 21606177
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Functional characteristics and tissue distribution pattern of organic cation transporter 2 (OCTN2), an organic cation/carnitine transporter.
    Wu X; Huang W; Prasad PD; Seth P; Rajan DP; Leibach FH; Chen J; Conway SJ; Ganapathy V
    J Pharmacol Exp Ther; 1999 Sep; 290(3):1482-92. PubMed ID: 10454528
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Expression and localization of carnitine/organic cation transporter OCTN1 and OCTN2 in ocular epithelium.
    Garrett Q; Xu S; Simmons PA; Vehige J; Flanagan JL; Willcox MD
    Invest Ophthalmol Vis Sci; 2008 Nov; 49(11):4844-9. PubMed ID: 18641280
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Combination of l-Carnitine with Lipophilic Linkage-Donating Gemcitabine Derivatives as Intestinal Novel Organic Cation Transporter 2-Targeting Oral Prodrugs.
    Wang G; Chen H; Zhao D; Ding D; Sun M; Kou L; Luo C; Zhang D; Yi X; Dong J; Wang J; Liu X; He Z; Sun J
    J Med Chem; 2017 Mar; 60(6):2552-2561. PubMed ID: 28234466
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Functional genetic diversity in the high-affinity carnitine transporter OCTN2 (SLC22A5).
    Urban TJ; Gallagher RC; Brown C; Castro RA; Lagpacan LL; Brett CM; Taylor TR; Carlson EJ; Ferrin TE; Burchard EG; Packman S; Giacomini KM
    Mol Pharmacol; 2006 Nov; 70(5):1602-11. PubMed ID: 16931768
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Carnitine/organic cation transporter OCTN2-mediated transport of carnitine in primary-cultured epididymal epithelial cells.
    Kobayashi D; Irokawa M; Maeda T; Tsuji A; Tamai I
    Reproduction; 2005 Dec; 130(6):931-7. PubMed ID: 16322553
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.