These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

164 related articles for article (PubMed ID: 21457080)

  • 1. Novel HIV-1 non-nucleoside reverse transcriptase inhibitors: a patent review (2005 - 2010).
    Zhan P; Liu X
    Expert Opin Ther Pat; 2011 May; 21(5):717-96. PubMed ID: 21457080
    [TBL] [Abstract][Full Text] [Related]  

  • 2. HIV-1 NNRTIs: structural diversity, pharmacophore similarity, and implications for drug design.
    Zhan P; Chen X; Li D; Fang Z; De Clercq E; Liu X
    Med Res Rev; 2013 Jun; 33 Suppl 1():E1-72. PubMed ID: 21523792
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Diphenyl ether non-nucleoside reverse transcriptase inhibitors with excellent potency against resistant mutant viruses and promising pharmacokinetic properties.
    Sweeney ZK; Kennedy-Smith JJ; Wu J; Arora N; Billedeau JR; Davidson JP; Fretland J; Hang JQ; Heilek GM; Harris SF; Hirschfeld D; Inbar P; Javanbakht H; Jernelius JA; Jin Q; Li Y; Liang W; Roetz R; Sarma K; Smith M; Stefanidis D; Su G; Suh JM; Villaseñor AG; Welch M; Zhang FJ; Klumpp K
    ChemMedChem; 2009 Jan; 4(1):88-99. PubMed ID: 19006142
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Novel HIV-1 non-nucleoside reverse transcriptase inhibitors: a patent review (2011-2014).
    Li X; Zhang L; Tian Y; Song Y; Zhan P; Liu X
    Expert Opin Ther Pat; 2014 Nov; 24(11):1199-227. PubMed ID: 25313716
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Non-nucleoside reverse transcriptase inhibitors (NNRTIs), their discovery, development, and use in the treatment of HIV-1 infection: a review of the last 20 years (1989-2009).
    de Béthune MP
    Antiviral Res; 2010 Jan; 85(1):75-90. PubMed ID: 19781578
    [TBL] [Abstract][Full Text] [Related]  

  • 6. [Non-nucleoside reverse transcriptase inhibitors].
    Joly V; Yeni P
    Ann Med Interne (Paris); 2000 Jun; 151(4):260-7. PubMed ID: 10922953
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Compilation and prevalence of mutations associated with resistance to non-nucleoside reverse transcriptase inhibitors.
    Tambuyzer L; Azijn H; Rimsky LT; Vingerhoets J; Lecocq P; Kraus G; Picchio G; de Béthune MP
    Antivir Ther; 2009; 14(1):103-9. PubMed ID: 19320243
    [TBL] [Abstract][Full Text] [Related]  

  • 8. [The application of structural optimization strategies in drug design of HIV NNRTIs].
    Wang L; Zhan P; Liu XY
    Yao Xue Xue Bao; 2012 Nov; 47(11):1409-22. PubMed ID: 23387070
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The effect of NNRTIs on HIV reverse transcriptase dimerization.
    Tachedjian G; Goff SP
    Curr Opin Investig Drugs; 2003 Aug; 4(8):966-73. PubMed ID: 14508881
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Novel pyridinone derivatives as non-nucleoside reverse transcriptase inhibitors (NNRTIs) with high potency against NNRTI-resistant HIV-1 strains.
    Li A; Ouyang Y; Wang Z; Cao Y; Liu X; Ran L; Li C; Li L; Zhang L; Qiao K; Xu W; Huang Y; Zhang Z; Tian C; Liu Z; Jiang S; Shao Y; Du Y; Ma L; Wang X; Liu J
    J Med Chem; 2013 May; 56(9):3593-608. PubMed ID: 23540737
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Novel fluorine-containing DAPY derivatives as potent HIV-1 NNRTIs: a patent evaluation of WO2014072419.
    Meng Q; Liu N; Huang B; Zhan P; Liu X
    Expert Opin Ther Pat; 2015; 25(12):1477-86. PubMed ID: 26415039
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Discovery and optimization of pyridazinone non-nucleoside inhibitors of HIV-1 reverse transcriptase.
    Sweeney ZK; Dunn JP; Li Y; Heilek G; Dunten P; Elworthy TR; Han X; Harris SF; Hirschfeld DR; Hogg JH; Huber W; Kaiser AC; Kertesz DJ; Kim W; Mirzadegan T; Roepel MG; Saito YD; Silva TM; Swallow S; Tracy JL; Villasenor A; Vora H; Zhou AS; Klumpp K
    Bioorg Med Chem Lett; 2008 Aug; 18(15):4352-4. PubMed ID: 18632268
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Discovery of potent HIV-1 non-nucleoside reverse transcriptase inhibitors from arylthioacetanilide structural motif.
    Li W; Li X; De Clercq E; Zhan P; Liu X
    Eur J Med Chem; 2015 Sep; 102():167-79. PubMed ID: 26276432
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Scaffold hopping in the rational design of novel HIV-1 non-nucleoside reverse transcriptase inhibitors.
    O'Meara JA; Jakalian A; LaPlante S; Bonneau PR; Coulombe R; Faucher AM; Guse I; Landry S; Racine J; Simoneau B; Thavonekham B; Yoakim C
    Bioorg Med Chem Lett; 2007 Jun; 17(12):3362-6. PubMed ID: 17451954
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Molecular and structural aspects of clinically relevant mutations related to the approved non-nucleoside inhibitors of HIV-1 reverse transcriptase.
    Alcaro S; Alteri C; Artese A; Ceccherini-Silberstein F; Costa G; Ortuso F; Parrotta L; Perno CF; Svicher V
    Drug Resist Updat; 2011 Jun; 14(3):141-9. PubMed ID: 21295512
    [TBL] [Abstract][Full Text] [Related]  

  • 16. New non-nucleoside reverse transcriptase inhibitors (NNRTIs) in development for the treatment of HIV infections.
    Pauwels R
    Curr Opin Pharmacol; 2004 Oct; 4(5):437-46. PubMed ID: 15351347
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Discovery of 3-{5-[(6-amino-1H-pyrazolo[3,4-b]pyridine-3-yl)methoxy]-2-chlorophenoxy}-5-chlorobenzonitrile (MK-4965): a potent, orally bioavailable HIV-1 non-nucleoside reverse transcriptase inhibitor with improved potency against key mutant viruses.
    Tucker TJ; Sisko JT; Tynebor RM; Williams TM; Felock PJ; Flynn JA; Lai MT; Liang Y; McGaughey G; Liu M; Miller M; Moyer G; Munshi V; Perlow-Poehnelt R; Prasad S; Reid JC; Sanchez R; Torrent M; Vacca JP; Wan BL; Yan Y
    J Med Chem; 2008 Oct; 51(20):6503-11. PubMed ID: 18826204
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Characteristics of a group of nonnucleoside reverse transcriptase inhibitors with structural diversity and potent anti-human immunodeficiency virus activity.
    Yang SS; Fliakas-Boltz V; Bader JP; Buckheit RW
    Leukemia; 1995 Oct; 9 Suppl 1():S75-85. PubMed ID: 7475321
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design of annulated pyrazoles as inhibitors of HIV-1 reverse transcriptase.
    Sweeney ZK; Harris SF; Arora SF; Javanbakht H; Li Y; Fretland J; Davidson JP; Billedeau JR; Gleason SK; Hirschfeld D; Kennedy-Smith JJ; Mirzadegan T; Roetz R; Smith M; Sperry S; Suh JM; Wu J; Tsing S; Villaseñor AG; Paul A; Su G; Heilek G; Hang JQ; Zhou AS; Jernelius JA; Zhang FJ; Klumpp K
    J Med Chem; 2008 Dec; 51(23):7449-58. PubMed ID: 19007201
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Substituted indoles as HIV-1 non-nucleoside reverse transcriptase inhibitors: a patent evaluation (WO2015044928).
    Li X; Gao P; Zhan P; Liu X
    Expert Opin Ther Pat; 2016 May; 26(5):629-35. PubMed ID: 26742549
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.