BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

142 related articles for article (PubMed ID: 21457557)

  • 1. Intracellular insulin in human tumors: examples and implications.
    Radulescu RT
    Diabetol Metab Syndr; 2011 Apr; 3(1):5. PubMed ID: 21457557
    [TBL] [Abstract][Full Text] [Related]  

  • 2. One for all and all for one: RB defends the cell while IDE, PTEN and IGFBP-7 antagonize insulin and IGFs to protect RB.
    Radulescu RT
    Med Hypotheses; 2007; 69(5):1018-20. PubMed ID: 17475416
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Immunohistochemical demonstration of the zinc metalloprotease insulin-degrading enzyme in normal and malignant human breast: correlation with tissue insulin levels.
    Radulescu RT; Hufnagel C; Luppa P; Hellebrand H; Kuo WL; Rosner MR; Harbeck N; Giersig C; Meindl A; Schmitt M; Weirich G
    Int J Oncol; 2007 Jan; 30(1):73-80. PubMed ID: 17143514
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Expression of metalloprotease insulin-degrading enzyme insulysin in normal and malignant human tissues.
    Yfanti C; Mengele K; Gkazepis A; Weirich G; Giersig C; Kuo WL; Tang WJ; Rosner M; Schmitt M
    Int J Mol Med; 2008 Oct; 22(4):421-31. PubMed ID: 18813847
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Regulation of protein degradation by insulin-degrading enzyme: analysis by small interfering RNA-mediated gene silencing.
    Fawcett J; Permana PA; Levy JL; Duckworth WC
    Arch Biochem Biophys; 2007 Dec; 468(1):128-33. PubMed ID: 17964527
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Active role for the vasculature in the delivery of insulin to skeletal muscle.
    Vincent MA; Clerk LH; Rattigan S; Clark MG; Barrett EJ
    Clin Exp Pharmacol Physiol; 2005 Apr; 32(4):302-7. PubMed ID: 15810996
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Retinoblastoma protein co-purifies with proteasomal insulin-degrading enzyme: implications for cell proliferation control.
    Radulescu RT; Duckworth WC; Levy JL; Fawcett J
    Biochem Biophys Res Commun; 2010 Apr; 395(2):196-9. PubMed ID: 20362553
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Protein phosphatase 2A negatively regulates insulin's metabolic signaling pathway by inhibiting Akt (protein kinase B) activity in 3T3-L1 adipocytes.
    Ugi S; Imamura T; Maegawa H; Egawa K; Yoshizaki T; Shi K; Obata T; Ebina Y; Kashiwagi A; Olefsky JM
    Mol Cell Biol; 2004 Oct; 24(19):8778-89. PubMed ID: 15367694
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inositolphosphoglycans (IPGs) as mediators of insulin's steroidogenic actions.
    Nestler JE
    J Basic Clin Physiol Pharmacol; 1998; 9(2-4):197-204. PubMed ID: 10212834
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Biological properties of an initial degradation product of insulin by insulin-degrading enzyme.
    Yonezawa K; Yokono K; Shii K; Hari J; Yaso S; Sakamoto T; Kawase Y; Akiyama H; Taketomi S; Baba S
    Endocrinology; 1989 Jan; 124(1):496-504. PubMed ID: 2642422
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Indirect effects of insulin in regulating glucose fluxes.
    Shi ZQ; Giacca A; Fisher SJ; Lekas M; Bilinski D; Van Delangeryt M; Lickley HL; Vranic M
    Adv Exp Med Biol; 1993; 334():151-68. PubMed ID: 8249680
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inactivation of the retinoblastoma susceptibility gene in non-small-cell lung cancer. The Lung Cancer Study Group.
    Reissmann PT; Koga H; Takahashi R; Figlin RA; Holmes EC; Piantadosi S; Cordon-Cardo C; Slamon DJ
    Oncogene; 1993 Jul; 8(7):1913-9. PubMed ID: 8390038
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of intracellular proteolysis by insulin in isolated rat hepatocytes. Possible role of internalized hormone.
    Draznin B; Trowbridge M
    J Biol Chem; 1982 Oct; 257(20):11988-93. PubMed ID: 6749850
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Insulin-degrading enzyme (IDE): a novel heat shock-like protein.
    Tundo GR; Sbardella D; Ciaccio C; Bianculli A; Orlandi A; Desimio MG; Arcuri G; Coletta M; Marini S
    J Biol Chem; 2013 Jan; 288(4):2281-9. PubMed ID: 23188819
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mechanism of retinoblastoma gene inactivation in the spectrum of neuroendocrine lung tumors.
    Gouyer V; Gazzéri S; Bolon I; Drevet C; Brambilla C; Brambilla E
    Am J Respir Cell Mol Biol; 1998 Feb; 18(2):188-96. PubMed ID: 9476905
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Differential inactivation of CDKN2 and Rb protein in non-small-cell and small-cell lung cancer cell lines.
    Kelley MJ; Nakagawa K; Steinberg SM; Mulshine JL; Kamb A; Johnson BE
    J Natl Cancer Inst; 1995 May; 87(10):756-61. PubMed ID: 7563154
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Non-esterified fatty acids and the liver: why is insulin secreted into the portal vein?
    Bergman RN
    Diabetologia; 2000 Jul; 43(7):946-52. PubMed ID: 10952470
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Pancreatic β-cell-specific deletion of insulin-degrading enzyme leads to dysregulated insulin secretion and β-cell functional immaturity.
    Fernández-Díaz CM; Merino B; López-Acosta JF; Cidad P; de la Fuente MA; Lobatón CD; Moreno A; Leissring MA; Perdomo G; Cózar-Castellano I
    Am J Physiol Endocrinol Metab; 2019 Nov; 317(5):E805-E819. PubMed ID: 31479304
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Epithelial cell-derived periostin functions as a tumor suppressor in gastric cancer through stabilizing p53 and E-cadherin proteins via the Rb/E2F1/p14ARF/Mdm2 signaling pathway.
    Lv H; Liu R; Fu J; Yang Q; Shi J; Chen P; Ji M; Shi B; Hou P
    Cell Cycle; 2014; 13(18):2962-74. PubMed ID: 25486483
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibition of insulin-degrading enzyme increases translocation of insulin to the nucleus in H35 rat hepatoma cells: evidence of a cytosolic pathway.
    Harada S; Smith RM; Smith JA; Jarett L
    Endocrinology; 1993 Jun; 132(6):2293-8. PubMed ID: 8504733
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.