175 related articles for article (PubMed ID: 21458571)
1. Natural history of disease in the YAC128 mouse reveals a discrete signature of pathology in Huntington disease.
Carroll JB; Lerch JP; Franciosi S; Spreeuw A; Bissada N; Henkelman RM; Hayden MR
Neurobiol Dis; 2011 Jul; 43(1):257-65. PubMed ID: 21458571
[TBL] [Abstract][Full Text] [Related]
2. Selective degeneration and nuclear localization of mutant huntingtin in the YAC128 mouse model of Huntington disease.
Van Raamsdonk JM; Murphy Z; Slow EJ; Leavitt BR; Hayden MR
Hum Mol Genet; 2005 Dec; 14(24):3823-35. PubMed ID: 16278236
[TBL] [Abstract][Full Text] [Related]
3. Early white matter abnormalities, progressive brain pathology and motor deficits in a novel knock-in mouse model of Huntington's disease.
Jin J; Peng Q; Hou Z; Jiang M; Wang X; Langseth AJ; Tao M; Barker PB; Mori S; Bergles DE; Ross CA; Detloff PJ; Zhang J; Duan W
Hum Mol Genet; 2015 May; 24(9):2508-27. PubMed ID: 25609071
[TBL] [Abstract][Full Text] [Related]
4. Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease.
Slow EJ; van Raamsdonk J; Rogers D; Coleman SH; Graham RK; Deng Y; Oh R; Bissada N; Hossain SM; Yang YZ; Li XJ; Simpson EM; Gutekunst CA; Leavitt BR; Hayden MR
Hum Mol Genet; 2003 Jul; 12(13):1555-67. PubMed ID: 12812983
[TBL] [Abstract][Full Text] [Related]
5. A whole brain longitudinal study in the YAC128 mouse model of Huntington's disease shows distinct trajectories of neurochemical, structural connectivity and volumetric changes.
Petrella LI; Castelhano JM; Ribeiro M; Sereno JV; Gonçalves SI; Laço MN; Hayden MR; Rego AC; Castelo-Branco M
Hum Mol Genet; 2018 Jun; 27(12):2125-2137. PubMed ID: 29668904
[TBL] [Abstract][Full Text] [Related]
6. Differential changes in thalamic and cortical excitatory synapses onto striatal spiny projection neurons in a Huntington disease mouse model.
Kolodziejczyk K; Raymond LA
Neurobiol Dis; 2016 Feb; 86():62-74. PubMed ID: 26621114
[TBL] [Abstract][Full Text] [Related]
7. Selective degeneration in YAC mouse models of Huntington disease.
Van Raamsdonk JM; Warby SC; Hayden MR
Brain Res Bull; 2007 Apr; 72(2-3):124-31. PubMed ID: 17352936
[TBL] [Abstract][Full Text] [Related]
8. Marked differences in neurochemistry and aggregates despite similar behavioural and neuropathological features of Huntington disease in the full-length BACHD and YAC128 mice.
Pouladi MA; Stanek LM; Xie Y; Franciosi S; Southwell AL; Deng Y; Butland S; Zhang W; Cheng SH; Shihabuddin LS; Hayden MR
Hum Mol Genet; 2012 May; 21(10):2219-32. PubMed ID: 22328089
[TBL] [Abstract][Full Text] [Related]
9. Structural and molecular myelination deficits occur prior to neuronal loss in the YAC128 and BACHD models of Huntington disease.
Teo RT; Hong X; Yu-Taeger L; Huang Y; Tan LJ; Xie Y; To XV; Guo L; Rajendran R; Novati A; Calaminus C; Riess O; Hayden MR; Nguyen HP; Chuang KH; Pouladi MA
Hum Mol Genet; 2016 Jul; 25(13):2621-2632. PubMed ID: 27126634
[TBL] [Abstract][Full Text] [Related]
10. Wild-type huntingtin ameliorates striatal neuronal atrophy but does not prevent other abnormalities in the YAC128 mouse model of Huntington disease.
Van Raamsdonk JM; Pearson J; Murphy Z; Hayden MR; Leavitt BR
BMC Neurosci; 2006 Dec; 7():80. PubMed ID: 17147801
[TBL] [Abstract][Full Text] [Related]
11. Altered adult hippocampal neurogenesis in the YAC128 transgenic mouse model of Huntington disease.
Simpson JM; Gil-Mohapel J; Pouladi MA; Ghilan M; Xie Y; Hayden MR; Christie BR
Neurobiol Dis; 2011 Feb; 41(2):249-60. PubMed ID: 20875859
[TBL] [Abstract][Full Text] [Related]
12. Cellular and subcellular localization of Huntingtin [corrected] aggregates in the brain of a rat transgenic for Huntington disease.
Petrasch-Parwez E; Nguyen HP; Löbbecke-Schumacher M; Habbes HW; Wieczorek S; Riess O; Andres KH; Dermietzel R; Von Hörsten S
J Comp Neurol; 2007 Apr; 501(5):716-30. PubMed ID: 17299753
[TBL] [Abstract][Full Text] [Related]
13. Caspase-6-Resistant Mutant Huntingtin Does not Rescue the Toxic Effects of Caspase-Cleavable Mutant Huntingtin in vivo.
Graham RK; Deng Y; Pouladi MA; Vaid K; Ehrnhoefer D; Southwell AL; Bissada N; Franciosi S; Hayden MR
J Huntingtons Dis; 2012; 1(2):243-60. PubMed ID: 25063333
[TBL] [Abstract][Full Text] [Related]
14. Automated deformation analysis in the YAC128 Huntington disease mouse model.
Lerch JP; Carroll JB; Spring S; Bertram LN; Schwab C; Hayden MR; Henkelman RM
Neuroimage; 2008 Jan; 39(1):32-9. PubMed ID: 17942324
[TBL] [Abstract][Full Text] [Related]
15. Altering cortical input unmasks synaptic phenotypes in the YAC128 cortico-striatal co-culture model of Huntington disease.
Schmidt ME; Buren C; Mackay JP; Cheung D; Dal Cengio L; Raymond LA; Hayden MR
BMC Biol; 2018 Jun; 16(1):58. PubMed ID: 29945611
[TBL] [Abstract][Full Text] [Related]
16. Levels of mutant huntingtin influence the phenotypic severity of Huntington disease in YAC128 mouse models.
Graham RK; Slow EJ; Deng Y; Bissada N; Lu G; Pearson J; Shehadeh J; Leavitt BR; Raymond LA; Hayden MR
Neurobiol Dis; 2006 Feb; 21(2):444-55. PubMed ID: 16230019
[TBL] [Abstract][Full Text] [Related]
17. Anti-semaphorin 4D immunotherapy ameliorates neuropathology and some cognitive impairment in the YAC128 mouse model of Huntington disease.
Southwell AL; Franciosi S; Villanueva EB; Xie Y; Winter LA; Veeraraghavan J; Jonason A; Felczak B; Zhang W; Kovalik V; Waltl S; Hall G; Pouladi MA; Smith ES; Bowers WJ; Zauderer M; Hayden MR
Neurobiol Dis; 2015 Apr; 76():46-56. PubMed ID: 25662335
[TBL] [Abstract][Full Text] [Related]
18. Antisense oligonucleotide-mediated correction of transcriptional dysregulation is correlated with behavioral benefits in the YAC128 mouse model of Huntington's disease.
Stanek LM; Yang W; Angus S; Sardi PS; Hayden MR; Hung GH; Bennett CF; Cheng SH; Shihabuddin LS
J Huntingtons Dis; 2013; 2(2):217-28. PubMed ID: 25063516
[TBL] [Abstract][Full Text] [Related]
19. Phosphorylation of huntingtin at Ser421 in YAC128 neurons is associated with protection of YAC128 neurons from NMDA-mediated excitotoxicity and is modulated by PP1 and PP2A.
Metzler M; Gan L; Mazarei G; Graham RK; Liu L; Bissada N; Lu G; Leavitt BR; Hayden MR
J Neurosci; 2010 Oct; 30(43):14318-29. PubMed ID: 20980587
[TBL] [Abstract][Full Text] [Related]
20. Hip14l-deficient mice develop neuropathological and behavioural features of Huntington disease.
Sutton LM; Sanders SS; Butland SL; Singaraja RR; Franciosi S; Southwell AL; Doty CN; Schmidt ME; Mui KK; Kovalik V; Young FB; Zhang W; Hayden MR
Hum Mol Genet; 2013 Feb; 22(3):452-65. PubMed ID: 23077216
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
