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2. Prostaglandin PGE2 at very low concentrations suppresses collagen cleavage in cultured human osteoarthritic articular cartilage: this involves a decrease in expression of proinflammatory genes, collagenases and COL10A1, a gene linked to chondrocyte hypertrophy. Tchetina EV; Di Battista JA; Zukor DJ; Antoniou J; Poole AR Arthritis Res Ther; 2007; 9(4):R75. PubMed ID: 17683641 [TBL] [Abstract][Full Text] [Related]
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