492 related articles for article (PubMed ID: 21460630)
1. ULK1 inhibits mTORC1 signaling, promotes multisite Raptor phosphorylation and hinders substrate binding.
Dunlop EA; Hunt DK; Acosta-Jaquez HA; Fingar DC; Tee AR
Autophagy; 2011 Jul; 7(7):737-47. PubMed ID: 21460630
[TBL] [Abstract][Full Text] [Related]
2. RhoA modulates signaling through the mechanistic target of rapamycin complex 1 (mTORC1) in mammalian cells.
Gordon BS; Kazi AA; Coleman CS; Dennis MD; Chau V; Jefferson LS; Kimball SR
Cell Signal; 2014 Mar; 26(3):461-7. PubMed ID: 24316235
[TBL] [Abstract][Full Text] [Related]
3. Intestinal cell kinase (ICK) promotes activation of mTOR complex 1 (mTORC1) through phosphorylation of Raptor Thr-908.
Wu D; Chapman JR; Wang L; Harris TE; Shabanowitz J; Hunt DF; Fu Z
J Biol Chem; 2012 Apr; 287(15):12510-9. PubMed ID: 22356909
[TBL] [Abstract][Full Text] [Related]
4. The association of AMPK with ULK1 regulates autophagy.
Lee JW; Park S; Takahashi Y; Wang HG
PLoS One; 2010 Nov; 5(11):e15394. PubMed ID: 21072212
[TBL] [Abstract][Full Text] [Related]
5. Computational analysis of an autophagy/translation switch based on mutual inhibition of MTORC1 and ULK1.
SzymaĆska P; Martin KR; MacKeigan JP; Hlavacek WS; Lipniacki T
PLoS One; 2015; 10(3):e0116550. PubMed ID: 25761126
[TBL] [Abstract][Full Text] [Related]
6. The proline-rich Akt substrate of 40 kDa (PRAS40) is a physiological substrate of mammalian target of rapamycin complex 1.
Oshiro N; Takahashi R; Yoshino K; Tanimura K; Nakashima A; Eguchi S; Miyamoto T; Hara K; Takehana K; Avruch J; Kikkawa U; Yonezawa K
J Biol Chem; 2007 Jul; 282(28):20329-39. PubMed ID: 17517883
[TBL] [Abstract][Full Text] [Related]
7. ULK1 inhibits the kinase activity of mTORC1 and cell proliferation.
Jung CH; Seo M; Otto NM; Kim DH
Autophagy; 2011 Oct; 7(10):1212-21. PubMed ID: 21795849
[TBL] [Abstract][Full Text] [Related]
8. PRAS40 regulates mTORC1 kinase activity by functioning as a direct inhibitor of substrate binding.
Wang L; Harris TE; Roth RA; Lawrence JC
J Biol Chem; 2007 Jul; 282(27):20036-44. PubMed ID: 17510057
[TBL] [Abstract][Full Text] [Related]
9. mTORC1 phosphorylates the ULK1-mAtg13-FIP200 autophagy regulatory complex.
Chan EY
Sci Signal; 2009 Aug; 2(84):pe51. PubMed ID: 19690328
[TBL] [Abstract][Full Text] [Related]
10. Characterization of the Raptor/4E-BP1 interaction by chemical cross-linking coupled with mass spectrometry analysis.
Coffman K; Yang B; Lu J; Tetlow AL; Pelliccio E; Lu S; Guo DC; Tang C; Dong MQ; Tamanoi F
J Biol Chem; 2014 Feb; 289(8):4723-34. PubMed ID: 24403073
[TBL] [Abstract][Full Text] [Related]
11. Inhibition of mTOR kinase by AZD8055 can antagonize chemotherapy-induced cell death through autophagy induction and down-regulation of p62/sequestosome 1.
Huang S; Yang ZJ; Yu C; Sinicrope FA
J Biol Chem; 2011 Nov; 286(46):40002-12. PubMed ID: 21949121
[TBL] [Abstract][Full Text] [Related]
12. Hydrogen peroxide impairs insulin-stimulated assembly of mTORC1.
Zhang L; Kimball SR; Jefferson LS; Shenberger JS
Free Radic Biol Med; 2009 Jun; 46(11):1500-9. PubMed ID: 19281842
[TBL] [Abstract][Full Text] [Related]
13. Mechanistic target of rapamycin complex 1 (mTORC1)-mediated phosphorylation is governed by competition between substrates for interaction with raptor.
Dennis MD; Kimball SR; Jefferson LS
J Biol Chem; 2013 Jan; 288(1):10-9. PubMed ID: 23184952
[TBL] [Abstract][Full Text] [Related]
14. Regulation of mTOR complex 1 (mTORC1) by raptor Ser863 and multisite phosphorylation.
Foster KG; Acosta-Jaquez HA; Romeo Y; Ekim B; Soliman GA; Carriere A; Roux PP; Ballif BA; Fingar DC
J Biol Chem; 2010 Jan; 285(1):80-94. PubMed ID: 19864431
[TBL] [Abstract][Full Text] [Related]
15. Curcumin disrupts the Mammalian target of rapamycin-raptor complex.
Beevers CS; Chen L; Liu L; Luo Y; Webster NJ; Huang S
Cancer Res; 2009 Feb; 69(3):1000-8. PubMed ID: 19176385
[TBL] [Abstract][Full Text] [Related]
16. Alcohol and PRAS40 knockdown decrease mTOR activity and protein synthesis via AMPK signaling and changes in mTORC1 interaction.
Hong-Brown LQ; Brown CR; Kazi AA; Huber DS; Pruznak AM; Lang CH
J Cell Biochem; 2010 Apr; 109(6):1172-84. PubMed ID: 20127721
[TBL] [Abstract][Full Text] [Related]
17. The ULK1 complex mediates MTORC1 signaling to the autophagy initiation machinery via binding and phosphorylating ATG14.
Park JM; Jung CH; Seo M; Otto NM; Grunwald D; Kim KH; Moriarity B; Kim YM; Starker C; Nho RS; Voytas D; Kim DH
Autophagy; 2016; 12(3):547-64. PubMed ID: 27046250
[TBL] [Abstract][Full Text] [Related]
18. TOS motif-mediated raptor binding regulates 4E-BP1 multisite phosphorylation and function.
Schalm SS; Fingar DC; Sabatini DM; Blenis J
Curr Biol; 2003 May; 13(10):797-806. PubMed ID: 12747827
[TBL] [Abstract][Full Text] [Related]
19. Mammalian target of rapamycin complex 1-mediated phosphorylation of eukaryotic initiation factor 4E-binding protein 1 requires multiple protein-protein interactions for substrate recognition.
Dunlop EA; Dodd KM; Seymour LA; Tee AR
Cell Signal; 2009 Jul; 21(7):1073-84. PubMed ID: 19272448
[TBL] [Abstract][Full Text] [Related]
20. GSK3-mediated raptor phosphorylation supports amino-acid-dependent mTORC1-directed signalling.
Stretton C; Hoffmann TM; Munson MJ; Prescott A; Taylor PM; Ganley IG; Hundal HS
Biochem J; 2015 Sep; 470(2):207-21. PubMed ID: 26348909
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]