203 related articles for article (PubMed ID: 21460804)
61. Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids.
Sancak Y; Bar-Peled L; Zoncu R; Markhard AL; Nada S; Sabatini DM
Cell; 2010 Apr; 141(2):290-303. PubMed ID: 20381137
[TBL] [Abstract][Full Text] [Related]
62. Alkaline stress-induced autophagy is mediated by mTORC1 inactivation.
Suk J; Kwak SS; Lee JH; Choi JH; Lee SH; Lee DH; Byun B; Lee GH; Joe CO
J Cell Biochem; 2011 Sep; 112(9):2566-73. PubMed ID: 21590709
[TBL] [Abstract][Full Text] [Related]
63. SLC38A9: A lysosomal amino acid transporter at the core of the amino acid-sensing machinery that controls MTORC1.
Rebsamen M; Superti-Furga G
Autophagy; 2016 Jun; 12(6):1061-2. PubMed ID: 26431368
[TBL] [Abstract][Full Text] [Related]
64. TBC1D7 is a third subunit of the TSC1-TSC2 complex upstream of mTORC1.
Dibble CC; Elis W; Menon S; Qin W; Klekota J; Asara JM; Finan PM; Kwiatkowski DJ; Murphy LO; Manning BD
Mol Cell; 2012 Aug; 47(4):535-46. PubMed ID: 22795129
[TBL] [Abstract][Full Text] [Related]
65. A cell-penetrating ester of the neural metabolite lanthionine ketimine stimulates autophagy through the mTORC1 pathway: Evidence for a mechanism of action with pharmacological implications for neurodegenerative pathologies.
Harris-White ME; Ferbas KG; Johnson MF; Eslami P; Poteshkina A; Venkova K; Christov A; Hensley K
Neurobiol Dis; 2015 Dec; 84():60-8. PubMed ID: 25779968
[TBL] [Abstract][Full Text] [Related]
66. mTORC1: turning off is just as important as turning on.
Benjamin D; Hall MN
Cell; 2014 Feb; 156(4):627-8. PubMed ID: 24529368
[TBL] [Abstract][Full Text] [Related]
67. Computational analysis of an autophagy/translation switch based on mutual inhibition of MTORC1 and ULK1.
Szymańska P; Martin KR; MacKeigan JP; Hlavacek WS; Lipniacki T
PLoS One; 2015; 10(3):e0116550. PubMed ID: 25761126
[TBL] [Abstract][Full Text] [Related]
68. Fatty acids are novel nutrient factors to regulate mTORC1 lysosomal localization and apoptosis in podocytes.
Yasuda M; Tanaka Y; Kume S; Morita Y; Chin-Kanasaki M; Araki H; Isshiki K; Araki S; Koya D; Haneda M; Kashiwagi A; Maegawa H; Uzu T
Biochim Biophys Acta; 2014 Jul; 1842(7):1097-108. PubMed ID: 24726883
[TBL] [Abstract][Full Text] [Related]
69. Activity-independent targeting of mTOR to lysosomes in primary osteoclasts.
Wang A; Carraro-Lacroix LR; Owen C; Gao B; Corey PN; Tyrrell P; Brumell JH; Voronov I
Sci Rep; 2017 Jun; 7(1):3005. PubMed ID: 28592812
[TBL] [Abstract][Full Text] [Related]
70. MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB.
Martina JA; Chen Y; Gucek M; Puertollano R
Autophagy; 2012 Jun; 8(6):903-14. PubMed ID: 22576015
[TBL] [Abstract][Full Text] [Related]
71. Enhanced translation expands the endo-lysosome size and promotes antigen presentation during phagocyte activation.
Hipolito VEB; Diaz JA; Tandoc KV; Oertlin C; Ristau J; Chauhan N; Saric A; Mclaughlan S; Larsson O; Topisirovic I; Botelho RJ
PLoS Biol; 2019 Dec; 17(12):e3000535. PubMed ID: 31800587
[TBL] [Abstract][Full Text] [Related]
72. Proton-assisted amino acid transporter PAT1 complexes with Rag GTPases and activates TORC1 on late endosomal and lysosomal membranes.
Ögmundsdóttir MH; Heublein S; Kazi S; Reynolds B; Visvalingam SM; Shaw MK; Goberdhan DC
PLoS One; 2012; 7(5):e36616. PubMed ID: 22574197
[TBL] [Abstract][Full Text] [Related]
73. MTOR, PIK3C3, and autophagy: Signaling the beginning from the end.
Munson MJ; Ganley IG
Autophagy; 2015; 11(12):2375-6. PubMed ID: 26565689
[TBL] [Abstract][Full Text] [Related]
74. Lysosomal cholesterol activates mTORC1 via an SLC38A9-Niemann-Pick C1 signaling complex.
Castellano BM; Thelen AM; Moldavski O; Feltes M; van der Welle RE; Mydock-McGrane L; Jiang X; van Eijkeren RJ; Davis OB; Louie SM; Perera RM; Covey DF; Nomura DK; Ory DS; Zoncu R
Science; 2017 Mar; 355(6331):1306-1311. PubMed ID: 28336668
[TBL] [Abstract][Full Text] [Related]
75. The cochaperone BAG3 coordinates protein synthesis and autophagy under mechanical strain through spatial regulation of mTORC1.
Kathage B; Gehlert S; Ulbricht A; Lüdecke L; Tapia VE; Orfanos Z; Wenzel D; Bloch W; Volkmer R; Fleischmann BK; Fürst DO; Höhfeld J
Biochim Biophys Acta Mol Cell Res; 2017 Jan; 1864(1):62-75. PubMed ID: 27756573
[TBL] [Abstract][Full Text] [Related]
76. Beyond indigestion: emerging roles for lysosome-based signaling in human disease.
Ferguson SM
Curr Opin Cell Biol; 2015 Aug; 35():59-68. PubMed ID: 25950843
[TBL] [Abstract][Full Text] [Related]
77. Cucurbitacin E Induces Autophagy via Downregulating mTORC1 Signaling and Upregulating AMPK Activity.
Zha QB; Zhang XY; Lin QR; Xu LH; Zhao GX; Pan H; Zhou D; Ouyang DY; Liu ZH; He XH
PLoS One; 2015; 10(5):e0124355. PubMed ID: 25970614
[TBL] [Abstract][Full Text] [Related]
78. AMPK -> ULK1 -> autophagy.
Roach PJ
Mol Cell Biol; 2011 Aug; 31(15):3082-4. PubMed ID: 21628530
[No Abstract] [Full Text] [Related]
79. Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2.
Feldman ME; Apsel B; Uotila A; Loewith R; Knight ZA; Ruggero D; Shokat KM
PLoS Biol; 2009 Feb; 7(2):e38. PubMed ID: 19209957
[TBL] [Abstract][Full Text] [Related]
80. AMDE-1 is a dual function chemical for autophagy activation and inhibition.
Li M; Yang Z; Vollmer LL; Gao Y; Fu Y; Liu C; Chen X; Liu P; Vogt A; Yin XM
PLoS One; 2015; 10(3):e0122083. PubMed ID: 25894744
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]