BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

235 related articles for article (PubMed ID: 21463515)

  • 1. Treatment of experimental adjuvant arthritis with a novel folate receptor-targeted folic acid-aminopterin conjugate.
    Lu Y; Stinnette TW; Westrick E; Klein PJ; Gehrke MA; Cross VA; Vlahov IR; Low PS; Leamon CP
    Arthritis Res Ther; 2011 Apr; 13(2):R56. PubMed ID: 21463515
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A new weapon against an old target.
    Fiehn C
    Arthritis Res Ther; 2011 Aug; 13(4):122. PubMed ID: 21861856
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Folate receptor-targeted aminopterin therapy is highly effective and specific in experimental models of autoimmune uveitis and autoimmune encephalomyelitis.
    Lu Y; Wollak KN; Cross VA; Westrick E; Wheeler LW; Stinnette TW; Vaughn JF; Hahn SJ; Xu LC; Vlahov IR; Leamon CP
    Clin Immunol; 2014 Jan; 150(1):64-77. PubMed ID: 24333534
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Antiinflammatory Activity of a Novel Folic Acid Targeted Conjugate of the mTOR Inhibitor Everolimus.
    Lu Y; Parker N; Kleindl PJ; Cross VA; Wollak K; Westrick E; Stinnette TW; Gehrke MA; Wang K; Santhapuram HK; You F; Hahn SJ; Vaughn JF; Klein PJ; Vlahov IR; Low PS; Leamon CP
    Mol Med; 2015 Jul; 21(1):584-96. PubMed ID: 26181632
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Efficacy and tolerability of folate-aminopterin therapy in a rat focal model of multiple sclerosis.
    Elo P; Li XG; Liljenbäck H; Gardberg M; Moisio O; Miner M; Virta J; Saraste A; Srinivasarao M; Pugh M; Low PS; Knuuti J; Jalkanen S; Airas L; Lu YJ; Roivainen A
    J Neuroinflammation; 2021 Jan; 18(1):30. PubMed ID: 33472663
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Targeting folate receptor beta on monocytes/macrophages renders rapid inflammation resolution independent of root causes.
    Lu YJ; Wheeler LW; Chu H; Kleindl PJ; Pugh M; You F; Rao S; Garcia G; Wu HY; da Cunha AP; Johnson R; Westrick E; Cross V; Lloyd A; Dircksen C; Klein PJ; Vlahov IR; Low PS; Leamon CP
    Cell Rep Med; 2021 Oct; 2(10):100422. PubMed ID: 34755134
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Methotrexate and aminopterin lack in vivo antimalarial activity against murine malaria species.
    Irungu B; Kiboi D; Langat B; Rukunga G; Wittlin S; Nzila A
    Exp Parasitol; 2009 Oct; 123(2):118-21. PubMed ID: 19527714
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design and regioselective synthesis of a new generation of targeted therapeutics. Part 3: Folate conjugates of aminopterin hydrazide for the treatment of inflammation.
    Vlahov IR; You F; Santhapuram HK; Wang Y; Vaughn JF; Hahn SJ; Kleindl PJ; Fan M; Leamon CP
    Bioorg Med Chem Lett; 2011 Feb; 21(4):1202-5. PubMed ID: 21236665
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Combined ROS Sensitive Folate Receptor Targeted Micellar Formulations of Curcumin Effective Against Rheumatoid Arthritis in Rat Model.
    Wang Y; Guo R; Zou M; Jiang L; Kong L; Zhao S; Zhang X; Wang W; Xu B
    Int J Nanomedicine; 2024; 19():4217-4234. PubMed ID: 38766660
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of dihydrofolate reductase from bacterial and vertebrate sources by folate, aminopterin, methotrexate and their 5-deaza analogues.
    Stone SR; Montgomery JA; Morrison JF
    Biochem Pharmacol; 1984 Jan; 33(2):175-9. PubMed ID: 6367748
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and antifolate activity of isoaminopterin.
    Nair MG; Mercer LP; Baugh CM
    J Med Chem; 1974 Dec; 17(12):1268-72. PubMed ID: 4214924
    [No Abstract]   [Full Text] [Related]  

  • 12. Folate Receptor-Targeted Dendrimer-Methotrexate Conjugate for Inflammatory Arthritis.
    Qi R; Majoros I; Misra AC; Koch AE; Campbell P; Marotte H; Bergin IL; Cao Z; Goonewardena S; Morry J; Zhang S; Beer M; Makidon P; Kotlyar A; Thomas TP; Baker JR
    J Biomed Nanotechnol; 2015 Aug; 11(8):1431-41. PubMed ID: 26295143
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and in vitro biological activity of new deaza analogues of folic acid, aminopterin, and methotrexate with an L-ornithine side chain.
    Rosowsky A; Forsch RA; Bader H; Freisheim JH
    J Med Chem; 1991 Apr; 34(4):1447-54. PubMed ID: 2016722
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Folate analogues altered in the C9-N10 bridge region: N10-Toxylisohomofolic acid and N10-Toxylisohomoaminopterin.
    Nair MG; O'Neal PC; Baugh CM; Kisliuk RL; Gaumont Y; Rodman M
    J Med Chem; 1978 Jul; 21(7):673-7. PubMed ID: 97383
    [No Abstract]   [Full Text] [Related]  

  • 15. Folate-targeted imaging of activated macrophages in rats with adjuvant-induced arthritis.
    Turk MJ; Breur GJ; Widmer WR; Paulos CM; Xu LC; Grote LA; Low PS
    Arthritis Rheum; 2002 Jul; 46(7):1947-55. PubMed ID: 12124880
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibition of murine thymidylate synthase and human dihydrofolate reductase by 5,8-dideaza analogues of folic acid and aminopterin.
    Hynes JB; Patil SA; Tomazic A; Kumar A; Pathak A; Tan XH; Li XQ; Ratnam M; Delcamp TJ; Freisheim JH
    J Med Chem; 1988 Feb; 31(2):449-54. PubMed ID: 3339615
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Syntheses and antifolate activity of 5-methyl-5-deaza analogues of aminopterin, methotrexate, folic acid, and N10-methylfolic acid.
    Piper JR; McCaleb GS; Montgomery JA; Kisliuk RL; Gaumont Y; Sirotnak FM
    J Med Chem; 1986 Jun; 29(6):1080-7. PubMed ID: 2423690
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and antifolate evaluation of the 10-propargyl derivatives of 5-deazafolic acid, 5-deazaaminopterin, and 5-methyl-5-deazaaminopterin.
    Piper JR; Malik ND; Rhee MS; Galivan J; Sirotnak FM
    J Med Chem; 1992 Jan; 35(2):332-7. PubMed ID: 1732551
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Evaluation of the novel folate receptor ligand [18F]fluoro-PEG-folate for macrophage targeting in a rat model of arthritis.
    Gent YY; Weijers K; Molthoff CF; Windhorst AD; Huisman MC; Smith DE; Kularatne SA; Jansen G; Low PS; Lammertsma AA; van der Laken CJ
    Arthritis Res Ther; 2013 Mar; 15(2):R37. PubMed ID: 23452511
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and in vitro antifolate activity of rotationally restricted aminopterin and methotrexate analogues.
    Rosowsky A; Forsch RA; Wright JE
    J Med Chem; 2004 Dec; 47(27):6958-63. PubMed ID: 15615544
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.