BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

255 related articles for article (PubMed ID: 21465666)

  • 21. alpha- and beta-substituted phosphonate analogs of LPA as autotaxin inhibitors.
    Cui P; McCalmont WF; Tomsig JL; Lynch KR; Macdonald TL
    Bioorg Med Chem; 2008 Mar; 16(5):2212-25. PubMed ID: 18082408
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Virtual screening approaches for the identification of non-lipid autotaxin inhibitors.
    Parrill AL; Echols U; Nguyen T; Pham TC; Hoeglund A; Baker DL
    Bioorg Med Chem; 2008 Feb; 16(4):1784-95. PubMed ID: 18036821
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Requirement of Osteopontin in the migration and protection against Taxol-induced apoptosis via the ATX-LPA axis in SGC7901 cells.
    Zhang R; Wang J; Ma S; Huang Z; Zhang G
    BMC Cell Biol; 2011 Mar; 12():11. PubMed ID: 21406114
    [TBL] [Abstract][Full Text] [Related]  

  • 24. S32826, a nanomolar inhibitor of autotaxin: discovery, synthesis and applications as a pharmacological tool.
    Ferry G; Moulharat N; Pradère JP; Desos P; Try A; Genton A; Giganti A; Beucher-Gaudin M; Lonchampt M; Bertrand M; Saulnier-Blache JS; Tucker GC; Cordi A; Boutin JA
    J Pharmacol Exp Ther; 2008 Dec; 327(3):809-19. PubMed ID: 18755937
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Therapeutic potential of autotaxin/lysophospholipase d inhibitors.
    Federico L; Pamuklar Z; Smyth SS; Morris AJ
    Curr Drug Targets; 2008 Aug; 9(8):698-708. PubMed ID: 18691016
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Cancer cell expression of autotaxin controls bone metastasis formation in mouse through lysophosphatidic acid-dependent activation of osteoclasts.
    David M; Wannecq E; Descotes F; Jansen S; Deux B; Ribeiro J; Serre CM; Grès S; Bendriss-Vermare N; Bollen M; Saez S; Aoki J; Saulnier-Blache JS; Clézardin P; Peyruchaud O
    PLoS One; 2010 Mar; 5(3):e9741. PubMed ID: 20305819
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Optimization of a pipemidic acid autotaxin inhibitor.
    Hoeglund AB; Bostic HE; Howard AL; Wanjala IW; Best MD; Baker DL; Parrill AL
    J Med Chem; 2010 Feb; 53(3):1056-66. PubMed ID: 20041668
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Inhibition of autotaxin by lysophosphatidic acid and sphingosine 1-phosphate.
    van Meeteren LA; Ruurs P; Christodoulou E; Goding JW; Takakusa H; Kikuchi K; Perrakis A; Nagano T; Moolenaar WH
    J Biol Chem; 2005 Jun; 280(22):21155-61. PubMed ID: 15769751
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Involvement of the lysophosphatidic acid-generating enzyme autotaxin in lymphocyte-endothelial cell interactions.
    Nakasaki T; Tanaka T; Okudaira S; Hirosawa M; Umemoto E; Otani K; Jin S; Bai Z; Hayasaka H; Fukui Y; Aozasa K; Fujita N; Tsuruo T; Ozono K; Aoki J; Miyasaka M
    Am J Pathol; 2008 Nov; 173(5):1566-76. PubMed ID: 18818380
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Regulation and biological activities of the autotaxin-LPA axis.
    van Meeteren LA; Moolenaar WH
    Prog Lipid Res; 2007 Mar; 46(2):145-60. PubMed ID: 17459484
    [TBL] [Abstract][Full Text] [Related]  

  • 31. ATX-LPA axis induces expression of OPN in hepatic cancer cell SMMC7721.
    Zhang R; Zhang Z; Pan X; Huang X; Huang Z; Zhang G
    Anat Rec (Hoboken); 2011 Mar; 294(3):406-11. PubMed ID: 21337710
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Targeting melanoma growth and viability reveals dualistic functionality of the phosphonothionate analogue of carba cyclic phosphatidic acid.
    Altman MK; Gopal V; Jia W; Yu S; Hall H; Mills GB; McGinnis AC; Bartlett MG; Jiang G; Madan D; Prestwich GD; Xu Y; Davies MA; Murph MM
    Mol Cancer; 2010 Jun; 9():140. PubMed ID: 20529378
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Autotaxin signaling via lysophosphatidic acid receptors contributes to vascular endothelial growth factor-induced endothelial cell migration.
    Ptaszynska MM; Pendrak ML; Stracke ML; Roberts DD
    Mol Cancer Res; 2010 Mar; 8(3):309-21. PubMed ID: 20197381
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Autotaxin (ATX): a multi-functional and multi-modular protein possessing enzymatic lysoPLD activity and matricellular properties.
    Yuelling LM; Fuss B
    Biochim Biophys Acta; 2008 Sep; 1781(9):525-30. PubMed ID: 18485925
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Autotaxin inhibitors: a perspective on initial medicinal chemistry efforts.
    Parrill AL; Baker DL
    Expert Opin Ther Pat; 2010 Dec; 20(12):1619-25. PubMed ID: 21047298
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Autotaxin is overexpressed in glioblastoma multiforme and contributes to cell motility of glioblastoma by converting lysophosphatidylcholine to lysophosphatidic acid.
    Kishi Y; Okudaira S; Tanaka M; Hama K; Shida D; Kitayama J; Yamori T; Aoki J; Fujimaki T; Arai H
    J Biol Chem; 2006 Jun; 281(25):17492-17500. PubMed ID: 16627485
    [TBL] [Abstract][Full Text] [Related]  

  • 37. A novel autotaxin inhibitor reduces lysophosphatidic acid levels in plasma and the site of inflammation.
    Gierse J; Thorarensen A; Beltey K; Bradshaw-Pierce E; Cortes-Burgos L; Hall T; Johnston A; Murphy M; Nemirovskiy O; Ogawa S; Pegg L; Pelc M; Prinsen M; Schnute M; Wendling J; Wene S; Weinberg R; Wittwer A; Zweifel B; Masferrer J
    J Pharmacol Exp Ther; 2010 Jul; 334(1):310-7. PubMed ID: 20392816
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Autotaxin, a secreted lysophospholipase D, is essential for blood vessel formation during development.
    van Meeteren LA; Ruurs P; Stortelers C; Bouwman P; van Rooijen MA; Pradère JP; Pettit TR; Wakelam MJ; Saulnier-Blache JS; Mummery CL; Moolenaar WH; Jonkers J
    Mol Cell Biol; 2006 Jul; 26(13):5015-22. PubMed ID: 16782887
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Boronic acid-based inhibitor of autotaxin reveals rapid turnover of LPA in the circulation.
    Albers HM; Dong A; van Meeteren LA; Egan DA; Sunkara M; van Tilburg EW; Schuurman K; van Tellingen O; Morris AJ; Smyth SS; Moolenaar WH; Ovaa H
    Proc Natl Acad Sci U S A; 2010 Apr; 107(16):7257-62. PubMed ID: 20360563
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Synthesis, pharmacology, and cell biology of sn-2-aminooxy analogues of lysophosphatidic acid.
    Gajewiak J; Tsukahara R; Fujiwara Y; Tigyi G; Prestwich GD
    Org Lett; 2008 Mar; 10(6):1111-4. PubMed ID: 18284246
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 13.