BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

329 related articles for article (PubMed ID: 21466675)

  • 21. Direct interaction of the Fanconi anaemia protein FANCG with BRCA2/FANCD1.
    Hussain S; Witt E; Huber PA; Medhurst AL; Ashworth A; Mathew CG
    Hum Mol Genet; 2003 Oct; 12(19):2503-10. PubMed ID: 12915460
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Evaluation of Fanconi Anemia genes in familial breast cancer predisposition.
    Seal S; Barfoot R; Jayatilake H; Smith P; Renwick A; Bascombe L; McGuffog L; Evans DG; Eccles D; Easton DF; Stratton MR; Rahman N;
    Cancer Res; 2003 Dec; 63(24):8596-9. PubMed ID: 14695169
    [TBL] [Abstract][Full Text] [Related]  

  • 23. PALB2 is an integral component of the BRCA complex required for homologous recombination repair.
    Sy SM; Huen MS; Chen J
    Proc Natl Acad Sci U S A; 2009 Apr; 106(17):7155-60. PubMed ID: 19369211
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Distinct roles of FANCO/RAD51C protein in DNA damage signaling and repair: implications for Fanconi anemia and breast cancer susceptibility.
    Somyajit K; Subramanya S; Nagaraju G
    J Biol Chem; 2012 Jan; 287(5):3366-80. PubMed ID: 22167183
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Ablation of the Brca1-Palb2 Interaction Phenocopies Fanconi Anemia in Mice.
    Park D; Bergin SM; Jones D; Ru P; Koivisto CS; Jeon YJ; Sizemore GM; Kladney RD; Hadjis A; Shakya R; Ludwig T
    Cancer Res; 2020 Oct; 80(19):4172-4184. PubMed ID: 32732220
    [TBL] [Abstract][Full Text] [Related]  

  • 26. RAD52 inactivation is synthetically lethal with deficiencies in BRCA1 and PALB2 in addition to BRCA2 through RAD51-mediated homologous recombination.
    Lok BH; Carley AC; Tchang B; Powell SN
    Oncogene; 2013 Jul; 32(30):3552-8. PubMed ID: 22964643
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Lack of large genomic deletions in BRIP1, PALB2, and FANCD2 genes in BRCA1/2 negative familial breast cancer.
    Ameziane N; van den Ouweland AM; Adank MA; Vijzelaar RN; Errami A; Dorsman JC; Joenje H; Meijers-Heijboer H; Waisfisz Q
    Breast Cancer Res Treat; 2009 Dec; 118(3):651-3. PubMed ID: 19504183
    [No Abstract]   [Full Text] [Related]  

  • 28. Direct interaction of FANCD2 with BRCA2 in DNA damage response pathways.
    Hussain S; Wilson JB; Medhurst AL; Hejna J; Witt E; Ananth S; Davies A; Masson JY; Moses R; West SC; de Winter JP; Ashworth A; Jones NJ; Mathew CG
    Hum Mol Genet; 2004 Jun; 13(12):1241-8. PubMed ID: 15115758
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Plasticity of BRCA2 function in homologous recombination: genetic interactions of the PALB2 and DNA binding domains.
    Siaud N; Barbera MA; Egashira A; Lam I; Christ N; Schlacher K; Xia B; Jasin M
    PLoS Genet; 2011 Dec; 7(12):e1002409. PubMed ID: 22194698
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Tracing the network connecting BRCA and Fanconi anaemia proteins.
    Venkitaraman AR
    Nat Rev Cancer; 2004 Apr; 4(4):266-76. PubMed ID: 15057286
    [No Abstract]   [Full Text] [Related]  

  • 31. A distinct replication fork protection pathway connects Fanconi anemia tumor suppressors to RAD51-BRCA1/2.
    Schlacher K; Wu H; Jasin M
    Cancer Cell; 2012 Jul; 22(1):106-16. PubMed ID: 22789542
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Functional evaluation of BRCA2 variants mapping to the PALB2-binding and C-terminal DNA-binding domains using a mouse ES cell-based assay.
    Biswas K; Das R; Eggington JM; Qiao H; North SL; Stauffer S; Burkett SS; Martin BK; Southon E; Sizemore SC; Pruss D; Bowles KR; Roa BB; Hunter N; Tessarollo L; Wenstrup RJ; Byrd RA; Sharan SK
    Hum Mol Genet; 2012 Sep; 21(18):3993-4006. PubMed ID: 22678057
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Biallelic mutations in PALB2 cause Fanconi anemia subtype FA-N and predispose to childhood cancer.
    Reid S; Schindler D; Hanenberg H; Barker K; Hanks S; Kalb R; Neveling K; Kelly P; Seal S; Freund M; Wurm M; Batish SD; Lach FP; Yetgin S; Neitzel H; Ariffin H; Tischkowitz M; Mathew CG; Auerbach AD; Rahman N
    Nat Genet; 2007 Feb; 39(2):162-4. PubMed ID: 17200671
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Functional interaction between the Fanconi Anemia D2 protein and proliferating cell nuclear antigen (PCNA) via a conserved putative PCNA interaction motif.
    Howlett NG; Harney JA; Rego MA; Kolling FW; Glover TW
    J Biol Chem; 2009 Oct; 284(42):28935-42. PubMed ID: 19704162
    [TBL] [Abstract][Full Text] [Related]  

  • 35. PALB2/FANCN: recombining cancer and Fanconi anemia.
    Tischkowitz M; Xia B
    Cancer Res; 2010 Oct; 70(19):7353-9. PubMed ID: 20858716
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Interaction with PALB2 Is Essential for Maintenance of Genomic Integrity by BRCA2.
    Hartford SA; Chittela R; Ding X; Vyas A; Martin B; Burkett S; Haines DC; Southon E; Tessarollo L; Sharan SK
    PLoS Genet; 2016 Aug; 12(8):e1006236. PubMed ID: 27490902
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Regulation of the activation of the Fanconi anemia pathway by the p21 cyclin-dependent kinase inhibitor.
    Rego MA; Harney JA; Mauro M; Shen M; Howlett NG
    Oncogene; 2012 Jan; 31(3):366-75. PubMed ID: 21685936
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Hereditary truncating mutations of DNA repair and other genes in BRCA1/BRCA2/PALB2-negatively tested breast cancer patients.
    Lhota F; Zemankova P; Kleiblova P; Soukupova J; Vocka M; Stranecky V; Janatova M; Hartmannova H; Hodanova K; Kmoch S; Kleibl Z
    Clin Genet; 2016 Oct; 90(4):324-33. PubMed ID: 26822949
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Heterozygous mutations in PALB2 cause DNA replication and damage response defects.
    Nikkilä J; Parplys AC; Pylkäs K; Bose M; Huo Y; Borgmann K; Rapakko K; Nieminen P; Xia B; Pospiech H; Winqvist R
    Nat Commun; 2013; 4():2578. PubMed ID: 24153426
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Replication Protein A (RPA) deficiency activates the Fanconi anemia DNA repair pathway.
    Jang SW; Jung JK; Kim JM
    Cell Cycle; 2016 Sep; 15(17):2336-45. PubMed ID: 27398742
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 17.